How to Travel from
Santiago del Estero to Cusco
by Plane, Route or Car
Schedule
Santiago del Estero, Argentina → Cusco, Peru
All
04 Jul 2026
July 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
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August 2026
Mon
Tue
Wed
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27
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6
September 2026
Mon
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31
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October 2026
Mon
Tue
Wed
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Fri
Sat
Sun
28
29
30
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November 2026
Mon
Tue
Wed
Thu
Fri
Sat
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26
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30
31
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30
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6
December 2026
Mon
Tue
Wed
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Sat
Sun
30
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30
31
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2
3
January 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
31
1
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31
February 2027
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March 2027
Mon
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4
April 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
31
1
2
3
4
5
6
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9
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30
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2
May 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
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29
30
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6
June 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
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All days
05 Jul, Sun
06 Jul, Mon
07 Jul, Tue
08 Jul, Wed
09 Jul, Thu
Cheapest and Fastest Ways to Travel from Santiago Del Estero to Cusco
Composite routes from Santiago Del Estero to Cusco
Cheapest
29 h 29 min
Car
2171 km.
from $119
Other
2 d 27 min
1776 km.
from $181.65
2 d 1 h 5 min
1776 km.
from $169.96
2 d 4 h 5 min
1776 km.
from $162.26
Route Navigator Santiago del Estero - Cusco
Get all the information you need right here
Continue onto Alvear
Alvear, 104 м
104 м
Turn right onto Leandro N. Alem
Leandro N. Alem, 149 м
149 м
Turn right onto Avenida Rivadavia
Avenida Rivadavia, 131 м
131 м
Turn right onto Avenida Belgrano Norte
Avenida Belgrano Norte, 1 km 456 м
1 km 456 м
At roundabout, take exit 1
296 м
296 м
At roundabout, take exit 1 onto Hipólito Yrigoyen
Hipólito Yrigoyen, 335 м
335 м
At roundabout, take exit 2 onto Ruta Nacional 64
Ruta Nacional 64, 2 km 598 м
2 km 598 м
At roundabout, take exit 2 onto Yugoslavia
Yugoslavia, 1 km 289 м
1 km 289 м
Turn left onto Camino a la Dársena
Camino a la Dársena, 6 km 110 м
6 km 110 м
Turn right onto RP8
1 km 508 м
1 km 508 м
Turn left
2 km 877 м
2 km 877 м
Keep left
5 km 667 м
5 km 667 м
Turn slight left onto Ruta Nacional 34
Ruta Nacional 34, 125 km 475 м
125 km 475 м
Keep left onto Ruta Nacional 34
Ruta Nacional 34, 110 km 97 м
110 km 97 м
Keep right onto Ruta Nacional 34
Ruta Nacional 34, 127 km 782 м
127 km 782 м
At roundabout, take exit 2 onto Ruta Nacional 34
Ruta Nacional 34, 32 km 374 м
32 km 374 м
Keep left onto Ruta Nacional 1V66
Ruta Nacional 1V66, 252 km 184 м
252 km 184 м
Continue onto Ruta Nacional 9
Ruta Nacional 9, 71 km 928 м
71 km 928 м
Turn right onto Avenida Paraguay
Avenida Paraguay, 351 м
351 м
Turn left onto Avenida Sarmiento
Avenida Sarmiento, 303 м
303 м
At roundabout, take exit 1 onto Avenida Sarmiento
Avenida Sarmiento, 401 м
401 м
At roundabout, take exit 1 onto Sanchez de Bustamante
Sanchez de Bustamante, 131 м
131 м
Turn left onto Avenida Internacional
Avenida Internacional, 1 km 344 м
1 km 344 м
At roundabout, take exit 3 onto Avenida Antofagasta
Avenida Antofagasta, 452 м
452 м
At roundabout, take exit 2 onto Avenida Antofagasta
Avenida Antofagasta, 1 km 935 м
1 km 935 м
At roundabout, take exit 2 onto Avenida Antofagasta
Avenida Antofagasta, 146 м
146 м
At roundabout, take exit 2 onto RN14: Tupiza-Villazón
RN14: Tupiza-Villazón, 88 km 637 м
88 km 637 м
At roundabout, take exit 1 onto Avenida José Luis San Juan García
Avenida José Luis San Juan García, 1 km 48 м
1 km 48 м
Turn slight right onto Avenida Circunvalación
Avenida Circunvalación, 3 km 99 м
3 km 99 м
At roundabout, take exit 2 onto RN21: Uyuni-Tupiza
RN21: Uyuni-Tupiza, 179 km 298 м
179 km 298 м
Keep left onto RN21: Uyuni-Tupiza
RN21: Uyuni-Tupiza, 10 km 741 м
10 km 741 м
At roundabout, take exit 2 onto Calle Ayacucho
Calle Ayacucho, 367 м
367 м
Turn right onto Calle Omiste
Calle Omiste, 101 м
101 м
Turn left onto Calle Avaroa
Calle Avaroa, 1 km 719 м
1 km 719 м
At roundabout, take exit 2 onto Calle Avaroa
Calle Avaroa, 1 km 859 м
1 km 859 м
Turn right onto Calle Fernando Alonzo
Calle Fernando Alonzo, 118 м
118 м
Turn left onto Calle Bolívar
Calle Bolívar, 119 м
119 м
Turn right onto Calle Boqueron
Calle Boqueron, 36 м
36 м
Turn left
9 м
9 м
Turn slight right
178 м
178 м
Keep left
177 м
177 м
Turn left
77 м
77 м
Turn right onto Calle Ballivián
Calle Ballivián, 55 м
55 м
Turn right onto Calle Camacho
Calle Camacho, 7 м
7 м
Make a U-turn onto Calle Camacho
Calle Camacho, 268 м
268 м
Turn slight right onto RN30: Challapata-Uyuni
RN30: Challapata-Uyuni, 197 km 532 м
197 km 532 м
Continue onto RN1: Machacamarquita-Challapata
RN1: Machacamarquita-Challapata, 92 km 731 м
92 km 731 м
Continue onto RN1: Machacamarquita-Challapata
RN1: Machacamarquita-Challapata, 20 km 992 м
20 km 992 м
At roundabout, take exit 3 onto Rotonda Vinto
Rotonda Vinto, 3 km 957 м
3 km 957 м
Keep right
42 м
42 м
At roundabout, take exit 1
36 м
36 м
Turn left
1 km 838 м
1 km 838 м
Keep right onto Avenida Villarroel
Avenida Villarroel, 128 м
128 м
At roundabout, take exit 3 onto Avenida Villarroel
Avenida Villarroel, 1 km 264 м
1 km 264 м
Turn right onto Avenida Circunvalación
Avenida Circunvalación, 3 km 520 м
3 km 520 м
At roundabout, take exit 2 onto Avenida Circunvalación
Avenida Circunvalación, 3 km 749 м
3 km 749 м
At roundabout, take exit 1 onto RN1: Ruta Nacional 1
RN1: Ruta Nacional 1, 38 km 346 м
38 km 346 м
Keep right onto Doble Vía La Paz-Oruro
Doble Vía La Paz-Oruro, 87 km 789 м
87 km 789 м
Keep left onto Doble Vía La Paz-Oruro
Doble Vía La Paz-Oruro, 58 km 63 м
58 km 63 м
Turn left
7 km 545 м
7 km 545 м
Turn right
13 km 990 м
13 km 990 м
At roundabout, take exit 1 onto Calle Saavedra
Calle Saavedra, 148 м
148 м
Turn sharp left onto Calle Teniente Amezaga
Calle Teniente Amezaga, 118 м
118 м
Turn sharp right onto Avenida Arica
Avenida Arica, 190 м
190 м
Turn left onto Avenida Ingavi
Avenida Ingavi, 1 km 733 м
1 km 733 м
Turn right onto Calle Pisagua
Calle Pisagua, 34 м
34 м
Turn left onto Avenida Antofagasta
Avenida Antofagasta, 2 km 789 м
2 km 789 м
Turn left onto Carretera Tacna - La Paz
Carretera Tacna - La Paz, 10 km 421 м
10 km 421 м
Turn right
381 м
381 м
Turn left
1 km 745 м
1 km 745 м
Turn left
6 km 260 м
6 km 260 м
Keep right
7 km 199 м
7 km 199 м
Turn left onto RN1: Desaguadero-El Alto
RN1: Desaguadero-El Alto, 40 km 184 м
40 km 184 м
Continue onto RN1: Desaguadero-El Alto
RN1: Desaguadero-El Alto, 25 km 528 м
25 km 528 м
Turn right
114 м
114 м
Turn left
326 м
326 м
Turn left onto Jirón El Puerto
Jirón El Puerto, 298 м
298 м
Turn right onto Avenida Cultura
Avenida Cultura, 67 km 662 м
67 km 662 м
Turn right onto Jirón Cusco
Jirón Cusco, 10 м
10 м
Turn left onto Jirón Chinchaya
Jirón Chinchaya, 1 km 869 м
1 km 869 м
Keep right onto Avenida Alfonso Ugarte
Avenida Alfonso Ugarte, 1 km 222 м
1 km 222 м
Turn slight right onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 45 km 693 м
45 km 693 м
Keep left
1 km 602 м
1 km 602 м
Keep right
116 м
116 м
Continue
1 km 554 м
1 km 554 м
Keep right
136 м
136 м
Turn slight left onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 28 km 466 м
28 km 466 м
At roundabout, take exit 2 onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 3 km 855 м
3 km 855 м
Turn right onto Avenida El Sol
Avenida El Sol, 1 km 208 м
1 km 208 м
At roundabout, take exit 2 onto Avenida El Sol
Avenida El Sol, 234 м
234 м
Turn left
434 м
434 м
Turn left onto Jirón Los Incas
Jirón Los Incas, 6 м
6 м
Turn slight left onto Jirón Cahuide
Jirón Cahuide, 5 м
5 м
Turn slight right onto Jirón Cahuide
Jirón Cahuide, 28 м
28 м
Turn right onto Avenida La Torre
Avenida La Torre, 1 km 258 м
1 km 258 м
Keep right
57 м
57 м
Keep right onto Jirón 2 de Mayo
Jirón 2 de Mayo, 52 м
52 м
Turn left onto Jirón 2 de Mayo
Jirón 2 de Mayo, 45 м
45 м
Turn slight right onto Jirón José Sabogal
Jirón José Sabogal, 27 м
27 м
Turn left onto Pasaje Limbani
Pasaje Limbani, 40 м
40 м
Turn right onto Jirón Cacique Andrés Ingaricona
Jirón Cacique Andrés Ingaricona, 105 м
105 м
Turn sharp left onto Avenida Alto de la Alianza
Avenida Alto de la Alianza, 47 м
47 м
Turn right
72 м
72 м
Turn slight left onto Jirón Hermilio Valdizán
Jirón Hermilio Valdizán, 215 м
215 м
Turn left onto Jirón Kolles
Jirón Kolles, 132 м
132 м
Turn right onto Avenida Juliaca
Avenida Juliaca, 1 km 586 м
1 km 586 м
Turn left
349 м
349 м
Turn right onto Avenida Tiquillaca
Avenida Tiquillaca, 18 м
18 м
Turn sharp left onto Avenida Juliaca
Avenida Juliaca, 9 km 116 м
9 km 116 м
At roundabout, take exit 2 onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 1 km 301 м
1 km 301 м
At roundabout, take exit 1 onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 19 km 513 м
19 km 513 м
Continue onto Avenida Circunvalación
Avenida Circunvalación, 6 km 729 м
6 km 729 м
At roundabout, take exit 2 onto Autopista Mártires del 4 de Noviembre
Autopista Mártires del 4 de Noviembre, 3 km 182 м
3 km 182 м
At roundabout, take exit 2 onto Avenida Manuel Nuñez Butron
Avenida Manuel Nuñez Butron, 2 km 790 м
2 km 790 м
Continue onto Manuel Nuñez Butron
Manuel Nuñez Butron, 211 м
211 м
Keep left onto Manuel Nuñez Butron
Manuel Nuñez Butron, 24 km 403 м
24 km 403 м
Continue onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 37 km 310 м
37 km 310 м
Continue onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 31 km 642 м
31 km 642 м
At roundabout, take exit 2 onto Avenida Los Incas
Avenida Los Incas, 3 km 260 м
3 km 260 м
At roundabout, take exit 3 onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 104 km 424 м
104 km 424 м
Continue onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 1 km 926 м
1 km 926 м
Continue onto Avenida Arequipa
Avenida Arequipa, 1 km 359 м
1 km 359 м
Turn slight right onto Jirón Alonso Toledo
Jirón Alonso Toledo, 261 м
261 м
Turn right onto Prolongación Cantenario
Prolongación Cantenario, 115 м
115 м
Turn left onto Avenida Manuel Callo Zevallos
Avenida Manuel Callo Zevallos, 2 km 570 м
2 km 570 м
Turn left
16 м
16 м
Turn right onto Vía de Evitamiento
Vía de Evitamiento, 88 km 683 м
88 km 683 м
Keep left onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 3 km 888 м
3 km 888 м
Keep left onto Avenida Mariano Santos
Avenida Mariano Santos, 1 km 321 м
1 km 321 м
Continue onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 16 km 842 м
16 km 842 м
Keep left onto Carretera Longitudinal de la Sierra Sur
Carretera Longitudinal de la Sierra Sur, 29 km 677 м
29 km 677 м
At roundabout, take exit 3 onto Avenida Garcilaso
Avenida Garcilaso, 160 м
160 м
Turn right
177 м
177 м
Arrive at destination
Transport providers
Bus operators
Found: 21
VI
Viatac
Website
VB
Via Bariloche
Website
BA
Balut
Website
FB
Flecha Bus
Website
TR
Tramat
Website
FB
Fono Bus
Website
LV
La Veloz Del Norte
Website
TI
Transporte Internacional Litoral
Website
BS
Brown SRL
Website
TT
Trans Tours Juarez
Website
EE
Expreso El Bermejeño
Website
TC
Trans Copacabana SA
Website
AS
Autotransportes SAMA
Website
TP
Transporte Platinum
Website
TS
Trans Salvador
Website
NC
Nuevo Continente Internacional
Website
PB
Pullman Bus
Website
BN
Buses Norte Grande
Website
PR
Peru Runa Travels
Website
ET
Expreso Turismo San Martin Nobleza
Website
FD
Frontera del Norte
Website
ET
Expreso Turismo San Martin Nobleza
15h 30m
Twice daily
$21.74–$29.35
+51 051 602 943
+51 051 602 943
Questions and Answers
What is the cheapest way to get from Santiago del Estero to Cusco?
The cheapest way to get from Santiago del Estero to Cusco is to bus which costs $92.39 - $173.91 and takes 2 days 0h.
What is the fastest way to get from Santiago del Estero to Cusco?
The fastest way to get from Santiago del Estero to Cusco is to fly which takes 10h 24m and costs $239.13 - $760.87 .
Is there a direct bus between Santiago del Estero and Cusco?
No, there is no direct bus from Santiago del Estero to Cusco station. However, there are services departing from Terminal de Ómnibus de Santiago del Estero and arriving at Cusco Bus Station via Terminal de Salta, Terminal Internacional and Tacna Bus Station. The journey, including transfers, takes approximately 2 days 0h.
How far is it from Santiago del Estero to Cusco?
The distance between Santiago del Estero and Cusco is 1779 km. The road distance is 2251.8 km.
How do I travel from Santiago del Estero to Cusco without a car?
The best way to get from Santiago del Estero to Cusco without a car is to bus which takes 2 days 0h and costs $92.39 - $173.91 .
How long does it take to get from Santiago del Estero to Cusco?
It takes approximately 10h 24m to get from Santiago del Estero to Cusco, including transfers.
Where do I catch the Santiago del Estero to Cusco bus from?
Santiago del Estero to Cusco bus services, operated by Flecha Bus, depart from Terminal de Ómnibus de Santiago del Estero station.
Bus or fly from Santiago del Estero to Cusco?
The best way to get from Santiago del Estero to Cusco is to fly which takes 10h 24m and costs $239.13 - $760.87 . Alternatively, you can bus, which costs $92.39 - $173.91 and takes 2 days 0h.
Where does the Santiago del Estero to Cusco bus arrive?
Santiago del Estero to Cusco bus services, operated by Flecha Bus, arrive at Terminal de Salta station.
What is the time difference between Santiago del Estero and Cusco?
Cusco is 2h behind Santiago del Estero. It is currently 09:49 in Santiago del Estero and 07:49 in Cusco.
Can I drive from Santiago del Estero to Cusco?
Yes, the driving distance between Santiago del Estero to Cusco is 2252 km. It takes approximately 29h 49m to drive from Santiago del Estero to Cusco.
Where can I stay near Cusco?
There are 1221+ hotels available in Cusco. Prices start at $27.51 per night.
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