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Addenbrooke's Hospital is a hospital in the city of Cambridge, UK, internationally recognised as a research and training centre.

It is one of the oldest medical and educational institutions - it was founded in 1766 by a bequest from Dr John Addenbrooke, a lecturer at Cambridge University, who left £4,500 for the founding of the hospital. For more than 200 years the hospital existed in a building in Trumpington Street, and it was only in 1976 it moved to the south side of the city and became part of the Cambridge Biomedical Centre, long called New Addenbrooke's. Old Addenbrooke's building now houses the business school.

The hospital is run by a trust which is not part of the University of Cambridge, but there are long-standing links between the university and the hospital and close co-operation. The university's medical school is also based in Addenbrooke's Hospital.

The clinic offers a wide range of medical services in a variety of different fields of medicine: transplantology, neurology, rare cancers, oral and maxillofacial surgery, and much more. Adjacent to Addenbrooke's, Rosie's Hospital specializes in maternity, obstetrics and gynecology. There are plans to build a Children's Medical Centre next to the Rosie Hospital.

Every two years, the Addenbrooke's Hospital organises an open day, when anyone can take a guided tour of parts of the clinic that are normally off-limits, starting with the roof of the building to the operating theatres and the morgue.