How to Travel from

Santiago to Popayan

by Plane, Route or Car

Chile Colombia Santiago Popayan

Schedule

Santiago, Chile → Popayan, Colombia

All

04 Jul 2026

July 2026

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January 2027

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05 Jul, Sun

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Cheapest

3 d 19 h 47 min

Car

6534 km.

from $359

Other

3 d 15 h 41 min

4040 km.

from $680.26

12 h 28 min

Bus, Plane

4040 km.

from $275.08

4 d 1 h 37 min

4040 km.

from $469.37

Route Navigator Santiago - Popayan

Get all the information you need right here

Continue onto Juan Esteban Montero

Juan Esteban Montero, 1 km 817 м

1 km 817 м

Turn right onto Avenida Américo Vespucio Sur

Avenida Américo Vespucio Sur, 1 km 546 м

1 km 546 м

Turn left onto Avenida Cristóbal Colón

Avenida Cristóbal Colón, 1 km 124 м

1 km 124 м

Keep right

58 м

Turn right onto Avenida Tobalaba

Avenida Tobalaba, 1 km 330 м

1 km 330 м

JetSMART

Website

LATAM Chile

Website

Avianca - Aerovías del Continente Americano S.A.

Website

Copa Airlines

Website

Easyfly

Website

JetSMART

Website

Duration 6h 2m

Frequency Monday, Wednesday, Friday, and Sunday

Estimated price $229.01–$572.52

LATAM Chile

Website

Duration 8h 6m

Frequency Thursday and Friday

Estimated price $330.79–$636.13

Avianca - Aerovías del Continente Americano S.A.

Website

Duration 11h 20m

Frequency Every day

Estimated price $203.56–$636.13

Copa Airlines

Website

Duration 10h 5m

Frequency Every day

Estimated price $305.34–$826.97

Easyfly

Website

Duration 10h 30m

Frequency Every day

Estimated price $203.56–$763.36

Andesmar

Website

Cruz Del Sur International

Website

Lineas de Los Andes

Website

Velotax

Website

Transipiales

Website

Sotracauca S.A.

Website

Cootranar

Website

Andesmar

Website

Duration 2d 5h

Frequency Twice a week

Estimated price $104.06–$330.79

Phone 0810 122 1122

Customer Service 0810 122 1122

Email [email protected]

Call Contact via email

Cruz Del Sur International

Website

Duration 2d 7h

Frequency Once daily

Estimated price $101.78–$178.12

Phone +51 1 311-5050

Customer Service +51 1 311-5050

Call

Lineas de Los Andes

Website

Duration 3d 12h

Frequency 3 times a week

Estimated price $445.29–$699.74

Phone +51 9 6788 4526

Customer Service +51 9 6788 4526

Email [email protected]

Call Contact via email

Velotax

Website

Duration 3h

Frequency Every 30 minutes

Estimated price $7.00–$13.99

Phone +57 333 033 4244

Customer Service +57 333 033 4244

Email [email protected]

Call Contact via email

Transipiales

Website

Duration 3h 30m

Frequency Every 2 hours

Estimated price $11.18–$15.27

Phone +57 317 441 0917

Customer Service +57 317 441 0917

Email [email protected]

Call Contact via email

Sotracauca S.A.

Website

Duration 3h 31m

Frequency 4 times a day

Estimated price $6.23–$8.27

Phone +57 31472618

Customer Service +57 31472618

Email [email protected]

Call Contact via email

Cootranar

Website

Duration 8h

Frequency Twice daily

Estimated price $23.77

Phone +57 314 8300861

Customer Service +57 314 8300861

Call

What is the cheapest way to get from Santiago to Popayán?

The cheapest way to get from Santiago to Popayán is to fly and bus which costs $184.78 - $413.04 and takes 12h 28m.

What is the fastest way to get from Santiago to Popayán?

The fastest way to get from Santiago to Popayán is to fly which takes 10h 55m and costs $173.91 - $478.26 .

Is there a direct bus between Santiago and Popayán?

No, there is no direct bus from Santiago to Popayán. However, there are services departing from Terminal Sur de Santiago and arriving at Terminal Popayán via Terminal de Transporte Cali. The journey, including transfers, takes approximately 3 days 15h.

How far is it from Santiago to Popayán?

The distance between Santiago and Popayán is 4046 km. The road distance is 5681.4 km.

How do I travel from Santiago to Popayán without a car?

The best way to get from Santiago to Popayán without a car is to bus which takes 3 days 15h and costs $380.43 - $597.83 .

How long does it take to get from Santiago to Popayán?

It takes approximately 10h 55m to get from Santiago to Popayán, including transfers.

Where do I catch the Santiago to Popayán bus from?

Santiago to Popayán bus services, operated by Lineas de Los Andes, depart from Terminal Sur de Santiago station.

Bus or fly from Santiago to Popayán?

The best way to get from Santiago to Popayán is to fly which takes 10h 55m and costs $173.91 - $478.26 . Alternatively, you can bus, which costs $380.43 - $597.83 and takes 3 days 15h.

Where does the Santiago to Popayán bus arrive?

Santiago to Popayán bus services, operated by Lineas de Los Andes, arrive at Terminal de Transporte Cali station.

What is the time difference between Santiago and Popayán?

Popayán is 2h behind Santiago. It is currently 09:45 in Santiago and 07:45 in Popayán.

Can I drive from Santiago to Popayán?

Yes, the driving distance between Santiago to Popayán is 5681 km. It takes approximately 3 days 3h to drive from Santiago to Popayán.

Where can I stay near Popayán?

There are 114+ hotels available in Popayán. Prices start at $11.93 per night.

Book in Popayan

Hotel Business Center Popayán

949 Cl. 9 Nte., Popayan

Ayenda Cafetal Arami

Carrera 10a, 1N - 63, Popayan

Lonova501 By Relajao in Popayán

Cl. 25 Nte. #2-40, Popayán, Cauca,, Popayan

All accommodation options in PopayanAll hotels

Popayan

Popayán is the capital of the Colombian department of Cauca. It is located in the Pubenza Valley in southwestern Colombia between the Western Mountain Range and Central Mountain Range. The municipality has a population of 318,059, an area of 483 km2, is located 1760 meters above sea level, and has an average temperature of 18 °C.

Read in Wikipedia

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Cheapest and Fastest Ways to Travel from Santiago to Popayan

Composite routes from Santiago to Popayan

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