How to Travel from
Santa Cruz to Melipilla
by Route or Car
Schedule
Santa Cruz, Chile → Melipilla, Chile
All
12 Jul 2026
July 2026
Mon
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August 2026
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September 2026
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October 2026
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November 2026
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December 2026
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January 2027
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February 2027
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March 2027
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April 2027
Mon
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May 2027
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June 2027
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All days
13 Jul, Mon
14 Jul, Tue
15 Jul, Wed
16 Jul, Thu
17 Jul, Fri
Cheapest and Fastest Ways to Travel from Santa Cruz to Melipilla
Composite routes from Santa Cruz to Melipilla
Cheapest
1 h 55 min
Car
125 km.
from $6
Other
3 h 59 min
106 km.
from $27.35
4 h 53 min
Bus, Train
105 km.
from $8.41
4 h 37 min
106 km.
from $14.07
5 h 45 min
106 km.
from $31.28
Route Navigator Santa Cruz - Melipilla
Get all the information you need right here
Continue onto 21 de Mayo
21 de Mayo, 70 м
70 м
Turn right onto Nicolás Palacios
Nicolás Palacios, 1 km 510 м
1 km 510 м
Turn right onto Nicolás Palacios
Nicolás Palacios, 8 km 12 м
8 km 12 м
Turn right onto San Elías
San Elías, 458 м
458 м
Continue onto Ruta I-340
Ruta I-340, 2 km 335 м
2 km 335 м
Continue onto Ruta H-82-I
Ruta H-82-I, 1 km 441 м
1 km 441 м
Turn sharp right onto Ruta H-82-I
Ruta H-82-I, 17 km 598 м
17 km 598 м
Turn left onto Ruta H-82-I
Ruta H-82-I, 18 km 65 м
18 km 65 м
Turn left onto Ruta de la Fruta
Ruta de la Fruta, 44 km 793 м
44 km 793 м
Keep right
199 м
199 м
Keep right
31 km 349 м
31 km 349 м
Turn sharp left and drive toward Melipilla
Melipilla, 142 м
142 м
Turn slight right onto Bypass Malipilla
Bypass Malipilla, 1 km 910 м
1 km 910 м
Turn left onto Camino Viejo
Camino Viejo, 210 м
210 м
Turn right onto Daniel Durán
Daniel Durán, 9 м
9 м
Turn left onto Manuel Rodríguez
Manuel Rodríguez, 33 м
33 м
Turn right onto Silva Chávez
Silva Chávez, 1 km 496 м
1 km 496 м
Turn right onto Libertad
Libertad, 126 м
126 м
Turn right onto Ortúzar
Ortúzar, 77 м
77 м
Arrive at destination
Transport providers
Questions and Answers
What is the cheapest way to get from Santa Cruz to Melipilla?
The cheapest way to get from Santa Cruz to Melipilla is to bus and train which costs $4.24 - $11.96 and takes 4h 53m.
What is the fastest way to get from Santa Cruz to Melipilla?
The fastest way to get from Santa Cruz to Melipilla is to drive which takes 1h 52m and costs $15.22 - $22.83 .
Is there a direct bus between Santa Cruz and Melipilla?
No, there is no direct bus from Santa Cruz to Melipilla. However, there are services departing from Hospital and arriving at Terminal de Buses de Melipilla via PI341-Parada 1 / and Terminal San Borja. The journey, including transfers, takes approximately 3h 59m.
How far is it from Santa Cruz to Melipilla?
The distance between Santa Cruz and Melipilla is 295 km. The road distance is 125.9 km.
How do I travel from Santa Cruz to Melipilla without a car?
The best way to get from Santa Cruz to Melipilla without a car is to bus which takes 3h 59m and costs $5.98 - $42.39 .
How long does it take to get from Santa Cruz to Melipilla?
It takes approximately 3h 59m to get from Santa Cruz to Melipilla, including transfers.
Where do I catch the Santa Cruz to Melipilla bus from?
Santa Cruz to Melipilla bus services, operated by Andimar, depart from Hospital station.
Where does the Santa Cruz to Melipilla bus arrive?
Santa Cruz to Melipilla bus services, operated by Andimar, arrive at Terminal Sur de Santiago station.
Can I drive from Santa Cruz to Melipilla?
Yes, the driving distance between Santa Cruz to Melipilla is 126 km. It takes approximately 1h 52m to drive from Santa Cruz to Melipilla.
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