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How to Travel from

Cali to Guayaquil

by Plane, Train, Bus, Rideshare, Route or Car

Cali
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Guayaquil
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Cali
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Guayaquil
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Schedule

Cali, Colombia → Guayaquil, Ecuador

All
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March 2026
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Seven ways to Travel from Cali to Guayaquil

Composite routes from Cali to Guayaquil

Cheapest
Other

Transport providers

Airlines

Avianca - Aerovías del Continente Americano S.A.

Website:
avianca.com/
Plane from Cali to José
Ave. Duration:
4h 4m
Frequency:
Every day
Estimated price:
$152.67–$610.68
Plane from Guillermo León Valencia Airport to José
Ave. Duration:
6h 11m
Frequency:
Every day
Estimated price:
$101.78–$368.96
Plane from Armenia to José
Ave. Duration:
5h 41m
Frequency:
Every day
Estimated price:
$101.78–$381.68
Plane from Pereira to José
Ave. Duration:
4h 10m
Frequency:
Every day
Estimated price:
$356.23–$1,017.81

Copa Airlines

Website:
copaair.com/
Plane from Cali to José
Ave. Duration:
5h 40m
Frequency:
Every day
Estimated price:
$178.12–$890.58
Plane from Armenia to José
Ave. Duration:
5h 48m
Frequency:
Tuesday, Thursday, and Sunday
Estimated price:
$139.95–$763.36
Plane from Pereira to José
Ave. Duration:
5h 48m
Frequency:
Every day
Estimated price:
$120.86–$610.68

Bus operators

Lineas de Los Andes

Phone:
+51 9 6788 4526
Website:
lineasdelosandes.com/
Bus from Terminal de Transporte Cali to Terminal
Ave. Duration:
22h
Frequency:
3 times a week
Estimated price:
$95.42–$120.86

Velotax

Phone:
+57 333 033 4244
Website:
velotax.com.co/
Bus from Terminal de Transporte Cali to Terminal
Ave. Duration:
3h
Frequency:
Every 30 minutes
Estimated price:
$7.00–$13.99

Transipiales

Phone:
+57 317 441 0917
Website:
transipialesvirtual.com/
Bus from Terminal de Transporte Cali to Terminal
Ave. Duration:
3h 30m
Frequency:
Every 2 hours
Estimated price:
$11.18–$15.27

Sotracauca S.A.

Phone:
+57 31472618
Website:
sotracauca.com/
Bus from Terminal de Transporte Cali to Terminal
Ave. Duration:
3h 31m
Frequency:
4 times a day
Estimated price:
$6.23–$8.27

Coomotoristas del Cauca

Phone:
0057 (2) 8232700
Website:
coomotoristas.com.co/sitio/
Bus from Cali to Popayan
Ave. Duration:
3h
Frequency:
Every 30 minutes
Estimated price:
$7.00

Tax Belalcazar

Phone:
+57 311 617 1013
Website:
taxbelalcazar.com.co/
Bus from Terminal de Transporte Cali to Armenia
Ave. Duration:
3h
Frequency:
Hourly
Estimated price:
$11.18

De Occidente

Phone:
+57 602 229 7017
Website:
deoccidente.com/
Bus from Terminal de Transporte Cali to Cartago
Ave. Duration:
3h
Frequency:
Hourly
Estimated price:
$10.74

Questions and Answers

What is the cheapest way to get from Cali to Guayaquil?

The cheapest way to get from Cali to Guayaquil is to drive which costs $59.78 - $92.39 and takes 17h 45m.

What is the fastest way to get from Cali to Guayaquil?

The fastest way to get from Cali to Guayaquil is to fly which takes 7h 23m and costs $108.70 - $260.87 .

Is there a direct bus between Cali and Guayaquil?

No, there is no direct bus from Cali to Guayaquil. However, there are services departing from Santa Monica and arriving at Terminal Terrestre de Guayaquil via Terminal de Transporte Cali. The journey, including transfers, takes approximately 23h 44m.

How far is it from Cali to Guayaquil?

The distance between Cali and Guayaquil is 774 km. The road distance is 1137.8 km.

How do I travel from Cali to Guayaquil without a car?

The best way to get from Cali to Guayaquil without a car is to bus which takes 23h 44m and costs $81.52 - $108.70 .

How long does it take to get from Cali to Guayaquil?

It takes approximately 7h 23m to get from Cali to Guayaquil, including transfers.

Where do I catch the Cali to Guayaquil bus from?

Cali to Guayaquil bus services, operated by Lineas de Los Andes, depart from Terminal de Transporte Cali station.

Bus or fly from Cali to Guayaquil?

The best way to get from Cali to Guayaquil is to fly which takes 7h 23m and costs $108.70 - $260.87 . Alternatively, you can bus, which costs $81.52 - $108.70 and takes 23h 44m.

Where does the Cali to Guayaquil bus arrive?

Cali to Guayaquil bus services, operated by Lineas de Los Andes, arrive at Terminal Terrestre de Guayaquil station.

Can I drive from Cali to Guayaquil?

Yes, the driving distance between Cali to Guayaquil is 1138 km. It takes approximately 17h 45m to drive from Cali to Guayaquil.

Where can I stay near Guayaquil?

There are 392+ hotels available in Guayaquil. Prices start at $26.72 per night.
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