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How to Travel from

Prague to Mytilene

by Plane, Route or Car

Prague
→
+0 →
Mytilene
Transport search to Mytilene
Simply select points
A and B, and we will create
a convenient route for you 👍
Czech Greece Prague Mytilene
Prague
→
+0 →
Mytilene
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
22 h 18 min
1968 km.
from $108
Composite Route Car Only
Schedule

Prague, Czech → Mytilene, Greece

All
07 Jul 2026
July 2026
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December 2026
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January 2027
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February 2027
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June 2027
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All days
08 Jul, Wed
09 Jul, Thu
10 Jul, Fri
11 Jul, Sat
12 Jul, Sun

Cheapest and Fastest Ways to Travel from Prague to Mytilene

Composite routes from Prague to Mytilene

Cheapest
22 h 18 min
Car
1968 km.
from $108
Other
22 h 44 min
Ferry
1548 km.
from $722.07
11 h 6 min
Bus, Plane
1548 km.
from $220.16
38 h 9 min
Bus, Ferry
1548 km.
Select a ticket
39 h 1 min
1548 km.
from $164.57

Transport providers

Bus operators
Found: 11
FlixBus
Website
Union Ivkoni
Website
Citylines
Website
Kaleia
Website
Simeonidis Tours
Website
Arda Tur
Website
Axios Travel
Website
FP Travel
Website
Metro Turizm
Website
Korona Travel
Website
Racic Eurobus
Website
FlixBus
Website
22h 50m
6 times a week
$108.70–$163.04
+49 30 300 137 300
+49 30 300 137 300
[email protected]
Call Contact via email
Union Ivkoni
Website
18h
Twice a week
$50.00–$81.52
07001 8282
07001 8282
[email protected]
Call Contact via email
Citylines
Website
7h
Twice daily
$20.65–$28.26
+3590885700870
+3590885700870
[email protected]
Call Contact via email
Kaleia
Website
5h 15m
Twice daily
+359 894 77 44 02
+359 894 77 44 02
[email protected]
Call Contact via email
Simeonidis Tours
Website
30h
Once a week
$81.52–$173.91
+30-2310540970
+30-2310540970
[email protected]
Call Contact via email
Arda Tur
Website
7h 15m
Once daily
$21.74–$31.52
0700 20 544
0700 20 544
Call
Axios Travel
Website
3h
On demand
+ 381 011 7555 675
+ 381 011 7555 675
[email protected]
Call Contact via email
FP Travel
Website
7h 30m
3 times a week
$54.35–$76.09
+302105233969
+302105233969
[email protected]
Call Contact via email
Metro Turizm
Website
8h 1m
3 times a day
$13.04–$18.48
0850 222 34 55
0850 222 34 55
[email protected]
Call Contact via email
Korona Travel
Website
23h 50m
Once a week
$95.45
+30 210 92 33 33
+30 210 92 33 33
[email protected]
Call Contact via email
Racic Eurobus
Website
21h
4 times a week
$76.09–$103.26
+359-887-208-506
+359-887-208-506
[email protected]
Call Contact via email
Airlines
Found: 4
Brussels Airlines
Website
Aegean Airlines
Website
Sky Express
Website
TUI Airlines Netherlands
Website
Brussels Airlines
Website
7h 5m
Friday
$152.17–$456.52
Aegean Airlines
Website
6h
Saturday
$81.52–$260.87
Sky Express
Website
5h 25m
Monday, Thursday, and Saturday
$70.65–$391.30
TUI Airlines Netherlands
Website
7h 35m
Tuesday
$141.30–$380.43
Train operators
Found: 7
Railjet
Website
ÖBB
Website
ÖBB EuroCity
Website
RegioJet
Website
Czech Railways (ČD)
Website
LEO Express
Website
Ukrainian Railways (UZ)
Website
Railjet
Website
2h 22m
Twice daily
$39.13–$59.78
+43 51717
+43 51717
Call
ÖBB
Website
2h 20m
Once daily
$46.74–$65.22
05 17 17
05 17 17
Call
ÖBB EuroCity
Website
2h 20m
Every 4 hours
$42.39–$59.78
+43 5 1717
+43 5 1717
Call
RegioJet
Website
4h 2m
4 times a day
$15.22–$51.09
+420 222 222 221
+420 222 222 221
[email protected]
Call Contact via email
Czech Railways (ČD)
Website
4h 7m
Every 4 hours
$30.43–$76.09
+420 221 111 122
+420 221 111 122
[email protected]
Call Contact via email
LEO Express
Website
2h 18m
Every 3 hours
$16.30–$29.35
+420 220 311 700
+420 220 311 700
[email protected]
Call Contact via email
Ukrainian Railways (UZ)
Website
2h 18m
Once daily
$36.96–$50.00
+38 (044) 309-70-01
+38 (044) 309-70-01
[email protected]
Call Contact via email
Other operators
Found: 4
Seajets
Website
Makri Travel
Website
Blue Star Ferries
Website
Hellenic Seaways
Website
Seajets
Website
7h 10m
Once a week
$86.96–$228.26
+30 210 4121001
+30 210 4121001
[email protected]
Call Contact via email
Makri Travel
Website
1h 15m
Once daily
$31.82
+30 694 415 6070
+30 694 415 6070
[email protected]
Call Contact via email
Blue Star Ferries
Website
2h 15m
Twice a week
$26.09–$81.52
+302108919800
+302108919800
[email protected]
Call Contact via email
Hellenic Seaways
Website
3h
Once daily
$27.17–$92.39
+30 210 89 19 800
+30 210 89 19 800
[email protected]
Call Contact via email

Questions and Answers

What is the cheapest way to get from Prague to Mytilene?

The cheapest way to get from Prague to Mytilene is to bus and ferry via Istanbul which costs $141.30 - $184.78 and takes 39h 1m.

What is the fastest way to get from Prague to Mytilene?

The fastest way to get from Prague to Mytilene is to fly which takes 7h 26m and costs $86.96 - $282.61 .

How far is it from Prague to Mytilene?

The distance between Prague and Mytilene is 1588 km.

How do I travel from Prague to Mytilene without a car?

The best way to get from Prague to Mytilene without a car is to train and shuttle and bus and car ferry which takes 25h 30m and costs .

How long does it take to get from Prague to Mytilene?

It takes approximately 7h 26m to get from Prague to Mytilene, including transfers.

Train, bus or fly from Prague to Mytilene?

The best way to get from Prague to Mytilene is to fly which takes 7h 26m and costs $86.96 - $282.61 . There are no good options to train or bus between Prague to Mytilene.

What is the time difference between Prague and Mytilene?

Mytilene is 1h ahead of Prague. It is currently 05:48 in Prague and 06:48 in Mytilene.

Where can I stay near Mytilene?

There are 312+ hotels available in Mytilene. Prices start at $37.11 per night.
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