How to Travel from
Mainz to Prague
by Plane, Bus, Route or Car
Schedule
Mainz, Germany → Prague, Czech
All
01 Jul 2026
July 2026
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August 2026
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September 2026
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October 2026
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November 2026
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December 2026
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January 2027
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February 2027
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May 2027
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June 2027
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All days
02 Jul, Thu
03 Jul, Fri
04 Jul, Sat
05 Jul, Sun
06 Jul, Mon
Cheapest and Fastest Ways to Travel from Mainz to Prague
Composite routes from Mainz to Prague
Cheapest
4 h 39 min
Car
541 km.
from $29
Other
3 h 54 min
Bus, Plane
437 km.
from $10.87
7 h 37 min
Train, Bus
438 km.
from $132.26
8 h 46 min
438 km.
Select a ticket
5 h 30 min
Bus, Plane
437 km.
from $196.85
Route Navigator Mainz - Prague
Get all the information you need right here
Continue onto Kaiserstraße
Kaiserstraße, 437 м
437 м
Turn right onto Bauhofstraße
Bauhofstraße, 304 м
304 м
Turn left onto Große Bleiche
Große Bleiche, 2 km 510 м
2 km 510 м
Keep left onto B 40
73 м
73 м
At roundabout, take exit 2 onto B 455
352 м
352 м
At roundabout, take exit 2 onto Ludwigsplatz
Ludwigsplatz, 4 km 384 м
4 km 384 м
Keep right and take A 66 toward Frankfurt, Köln
Frankfurt, Köln, A 66, 6 km 436 м
6 km 436 м
Keep right
22 м
22 м
Keep right and take A 3 toward Würzburg, Frankfurter Kreuz, Darmstadt
Würzburg, Frankfurter Kreuz, Darmstadt, A 3, 144 km 354 м
144 km 354 м
Keep right onto A 3
362 м
362 м
Keep left toward A 3
A 3, 429 м
429 м
Keep left and take A 3 toward Nürnberg, Kassel, Schweinfurt, Erfurt, Ulm, Rothenburg ob der Tauber
Nürnberg, Kassel, Schweinfurt, Erfurt, Ulm, Rothenburg ob der Tauber, A 3, 1 km 451 м
1 km 451 м
Keep left and take A 7 toward Nürnberg, Kassel, Erfurt, Schweinfurt
Nürnberg, Kassel, Erfurt, Schweinfurt, A 7, 417 м
417 м
Keep left onto A 3 and take A 3 toward Nürnberg, München
Nürnberg, München, A 3, 108 km 485 м
108 km 485 м
Keep right and take A 6 toward Prag, Amberg, Heilbronn, München
Prag, Amberg, Heilbronn, München, A 6, 149 м
149 м
Keep left and take A 6 toward Amberg, Prag
Amberg, Prag, A 6, 1 km 554 м
1 km 554 м
Keep right and take A 6 toward Amberg, Prag
Amberg, Prag, A 6, 1 km 509 м
1 km 509 м
Keep left and take A 6 toward Prag, Amberg
Prag, Amberg, A 6, 73 km 813 м
73 km 813 м
Keep right toward A 93
A 93, 318 м
318 м
Keep left and take A 93 toward Berlin, Dresden, Hof, Weiden
Berlin, Dresden, Hof, Weiden, A 93, 442 м
442 м
Keep left and take A 6 toward Prag, Waidhaus, Vohenstrauß
Prag, Waidhaus, Vohenstrauß, A 6, 103 km 171 м
103 km 171 м
Keep right
39 м
39 м
Keep left
346 м
346 м
Keep left
83 km 14 м
83 km 14 м
Keep right and drive toward Řepy, Stodůlky, Řeporyje
Řepy, Stodůlky, Řeporyje, 320 м
320 м
Keep left
42 м
42 м
Turn left onto Jeremiášova and drive toward Řepy, Zličín, ✈ letiště
Jeremiášova, Řepy, Zličín, ✈ letiště, 1 km 160 м
1 km 160 м
Turn right onto Plzeňská
Plzeňská, 6 km 821 м
6 km 821 м
Keep left onto Erbenova
Erbenova, 235 м
235 м
Turn right onto Holečkova
Holečkova, 1 km 285 м
1 km 285 м
Turn left onto náměstí Kinských
náměstí Kinských, 280 м
280 м
Turn sharp right onto Vítězná
Vítězná, 1 km 607 м
1 km 607 м
Turn left onto Smetanovo nábřeží
Smetanovo nábřeží, 1 km 532 м
1 km 532 м
Turn slight right onto Křižovnická
Křižovnická, 141 м
141 м
Turn right onto Platnéřská
Platnéřská, 332 м
332 м
Keep right onto Maiselova
Maiselova, 68 м
68 м
Turn right onto Jáchymova
Jáchymova, 88 м
88 м
Turn right onto Pařížská
Pařížská, 146 м
146 м
Arrive at destination
Transport providers
Bus operators
Found: 5
Questions and Answers
What is the cheapest way to get from Mainz to Prague?
The cheapest way to get from Mainz to Prague is to bus via Frankfurt am Main which costs $40.22 - $65.22 and takes 8h.
What is the fastest way to get from Mainz to Prague?
The fastest way to get from Mainz to Prague is to drive which takes 4h 37m and costs $92.39 - $141.30 .
Is there a direct bus between Mainz and Prague?
Yes, there is a direct bus departing from Mainz central train station station and arriving at Prague. Services depart once daily, and operate every day. The journey takes approximately 8h 5m.
Is there a direct train between Mainz and Prague?
No, there is no direct train from Mainz to Prague. However, there are services departing from Mainz, Hauptbahnhof and arriving at Praha Hlavni Nadrazi via Regensburg Hbf. The journey, including transfers, takes approximately 8h 46m.
How far is it from Mainz to Prague?
The distance between Mainz and Prague is 448 km. The road distance is 542 km.
How do I travel from Mainz to Prague without a car?
The best way to get from Mainz to Prague without a car is to train and bus which takes 7h 37m and costs $76.09 - $103.26 .
How long does it take to get from Mainz to Prague?
It takes approximately 3h 54m to get from Mainz to Prague, including transfers.
Where do I catch the Mainz to Prague bus from?
Mainz to Prague bus services, operated by FlixBus, depart from Mainz central train station.
Where do I catch the Mainz to Prague train from?
Mainz to Prague train services, operated by Deutsche Bahn Intercity-Express, depart from Mainz, Hauptbahnhof station.
Train or bus from Mainz to Prague?
The best way to get from Mainz to Prague is to train which takes 8h 46m and costs . Alternatively, you can bus via Frankfurt am Main, which costs $40.22 - $65.22 and takes 8h.
Where does the Mainz to Prague bus arrive?
Mainz to Prague bus services, operated by FlixBus, arrive at Prague station.
Where does the Mainz to Prague train arrive?
Mainz to Prague train services, operated by Deutsche Bahn Intercity-Express, arrive at Regensburg Hbf station.
Can I drive from Mainz to Prague?
Yes, the driving distance between Mainz to Prague is 542 km. It takes approximately 4h 37m to drive from Mainz to Prague.
How do I get a train ticket from Mainz to Prague?
Book your Mainz to Prague train tickets online with Omio.
How do I get a bus ticket from Mainz to Prague?
Book your Mainz to Prague bus tickets online with Omio and FlixBus.
Where can I stay near Prague?
There are 3498+ hotels available in Prague. Prices start at $26.51 per night.
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