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How to Travel from

Karlsruhe to Palermo

by Plane, Route or Car

Karlsruhe
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Palermo
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Karlsruhe
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Palermo
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20 h 29 min
1997 km.
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Schedule

Karlsruhe, Germany → Palermo, Italy

All
24 May 2026
May 2026
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December 2026
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January 2027
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Cheapest and Fastest Ways to Travel from Karlsruhe to Palermo

Composite routes from Karlsruhe to Palermo

Cheapest
Other

Transport providers

Airlines

Ryanair

Website:
ryanair.com/
Plane from Memmingen Airport to Palermo
Ave. Duration:
1h 55m
Frequency:
Monday, Thursday, Saturday, and Sunday
Estimated price:
$43.04–$253.16
Plane from Hahn to Palermo
Ave. Duration:
2h 15m
Frequency:
Monday and Saturday
Estimated price:
$51.90–$278.47

Lufthansa

Website:
lufthansa.com/
Plane from Stuttgart Airport to Palermo
Ave. Duration:
4h 50m
Frequency:
Friday to Sunday
Estimated price:
$177.21–$949.33
Plane from Frankfurt to Palermo
Ave. Duration:
2h 10m
Frequency:
Thursday and Saturday
Estimated price:
$303.79–$949.33

Eurowings

Website:
eurowings.com
Plane from Stuttgart Airport to Palermo
Ave. Duration:
2h 5m
Frequency:
Monday
Estimated price:
$107.59–$329.10

Swiss

Website:
swiss.com/
Plane from Stuttgart Airport to Palermo
Ave. Duration:
3h 45m
Frequency:
Monday, Thursday, Saturday, and Sunday
Estimated price:
$189.87–$822.76
Plane from Frankfurt to Palermo
Ave. Duration:
4h 35m
Frequency:
Monday, Thursday, Saturday, and Sunday
Estimated price:
$316.44–$949.33
Plane from Zurich Airport to Palermo
Ave. Duration:
1h 50m
Frequency:
Monday, Thursday, Saturday, and Sunday
Estimated price:
$215.18–$506.31

Alitalia

Website:
alitalia.com/
Plane from Frankfurt to Palermo
Ave. Duration:
3h 50m
Frequency:
Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
Estimated price:
$139.24–$354.42
Plane from Zurich Airport to Palermo
Ave. Duration:
3h 52m
Frequency:
Every day
Estimated price:
$88.60–$341.76

Bus operators

FlixBus

Phone:
+49 30 300 137 300
Website:
flixbus.com
Bus from Karlsruhe central train station to Stuttgart
Ave. Duration:
55 min
Frequency:
Hourly
Estimated price:
$10.13–$15.19
Bus from Karlsruhe central train station to Bologna
Ave. Duration:
12h 15m
Frequency:
Twice daily
Estimated price:
$75.95–$107.59

BlaBlaCar Bus

Phone:
+33 18 57 62 228
Website:
blablacar.co.uk/
Bus from Karlsruhe central train station to Stuttgart
Ave. Duration:
1h 15m
Frequency:
Once daily
Estimated price:
$12.66–$18.99

Union Ivkoni

Phone:
07001 8282
Website:
union-ivkoni.com/
Bus from Karlsruhe central train station to Stuttgart
Ave. Duration:
1h 15m
Frequency:
3 times a week
Estimated price:
$5.82–$9.49

Flibco

Phone:
+352 26 58 57 1
Website:
flibco.com/en
Bus from Mainz Short-term parking lot Am Schlag to Frankfurt
Ave. Duration:
1h 15m
Frequency:
Every 3 hours
Estimated price:
$13.92–$21.52

Arjani Travel

Phone:
+355 68 20 63 724
Website:
arjanitravel.com/
Bus from Karlsruhe central train station to Stuttgart
Ave. Duration:
1h 30m
Frequency:
Twice a week

Marino Autolinee

Phone:
+39 080 3112335
Website:
marinobus.it/
Bus from Karlsruhe Central Bus Station to Milano,
Ave. Duration:
11h 10m
Frequency:
Twice a week
Estimated price:
$54.43–$75.95

Autoservizi Salemi Srl

Phone:
(+39) 0923 98.11.20
Website:
autoservizisalemi.it/en/
Bus from Bologna Pzza xx Settembre to Palermo
Ave. Duration:
17h 15m
Frequency:
Once daily
Estimated price:
$41.77–$94.93
Bus from Milano, San Donato M3 to Palermo
Ave. Duration:
21h
Frequency:
Once daily
Estimated price:
$41.77–$107.59

Centrotrans Eurolines

Phone:
+387 33 770 889
Website:
centrotrans.com/
Bus from Karlsruhe central train station to Stuttgart
Ave. Duration:
1h 30m
Frequency:
3 times a week
Estimated price:
$7.59–$11.39

Train operators

TGV inOui

Phone:
+33 1 84 94 36 35
Website:
sncf-connect.com/en-en
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
37 min
Frequency:
3 times a day
Estimated price:
$25.32–$58.23
Train from Hauptbahnhof to Ulm
Ave. Duration:
1h 1m
Frequency:
Once daily
Estimated price:
$27.85–$60.76

NS

Phone:
+31 30 751 5155
Website:
ns.nl/
Train from Hauptbahnhof to Ulm
Ave. Duration:
40 min
Frequency:
Twice daily
Estimated price:
$15.19–$39.24

Deutsche Bahn Intercity-Express

Phone:
+49 30 311-682904
Website:
bahn.de/
Train from Karlsruhe Hauptbahnhof to Basel
Ave. Duration:
1h 48m
Frequency:
Hourly
Estimated price:
$50.63–$56.96
Train from Karlsruhe Hauptbahnhof to Frankfurt
Ave. Duration:
1h 6m
Frequency:
Every 4 hours
Estimated price:
$41.77–$46.83
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
57 min
Frequency:
Every 3 hours
Estimated price:
$34.18–$37.97
Train from Hauptbahnhof to Ulm
Ave. Duration:
42 min
Frequency:
Every 30 minutes
Estimated price:
$35.44–$39.24
Train from Ulm Hauptbahnhof to Memmingen
Ave. Duration:
28 min
Frequency:
Twice daily
Estimated price:
$29.11–$34.18
Train from Karlsruhe Hauptbahnhof to Mainz,
Ave. Duration:
1h 6m
Frequency:
Twice daily
Estimated price:
$41.77–$46.83
Train from Karlsruhe Hauptbahnhof to Singen
Ave. Duration:
2h 42m
Frequency:
4 times a week
Estimated price:
$53.16–$60.76

WESTbahn Gmbh

Phone:
+43 1 89900
Website:
westbahn.at/
Train from Hauptbahnhof to Ulm
Ave. Duration:
1h 2m
Frequency:
Twice daily
Estimated price:
$17.72–$40.50

Deutsche Bahn Regional

Phone:
+49 30 2970
Website:
bahn.de/
Train from Ulm Hauptbahnhof to Memmingen
Ave. Duration:
54 min
Frequency:
Hourly
Estimated price:
$13.92–$20.25
Train from Karlsruhe Hauptbahnhof to Singen
Ave. Duration:
2h 43m
Frequency:
Hourly
Estimated price:
$37.97–$53.16

Trenitalia Frecce

Phone:
+39 06 68475475
Website:
trenitalia.com/en/frecce.html
Train from Milan Centrale to Roma
Ave. Duration:
3h 17m
Frequency:
Every 30 minutes
Estimated price:
$49.37–$151.89
Train from Milano Rogoredo to Roma
Ave. Duration:
3h 29m
Frequency:
Hourly
Estimated price:
$49.37–$151.89

ItaloTreno

Phone:
+39 06 8937 1892
Website:
italotreno.it/it
Train from Milan Centrale to Roma
Ave. Duration:
3h 39m
Frequency:
Hourly
Estimated price:
$49.40–$120.25
Train from Milano Rogoredo to Roma
Ave. Duration:
3h 29m
Frequency:
Hourly
Estimated price:
$88.60–$120.25

Trenitalia Intercity

Phone:
+39 06 68475475
Website:
trenitalia.com/
Train from Milan Centrale to Roma
Ave. Duration:
7h 12m
Frequency:
Once daily
Estimated price:
$41.77–$56.96
Train from Roma Termini to Palermo
Ave. Duration:
11h 36m
Frequency:
Once daily
Estimated price:
$63.29–$88.60
Train from Milano Rogoredo to Roma
Ave. Duration:
7h
Frequency:
Once daily
Estimated price:
$41.77–$55.69

Swiss Railways (SBB/CFF/FFS)

Phone:
+41 848 44 66 88
Website:
sbb.ch/en
Train from Basel SBB to Lugano
Ave. Duration:
2h 55m
Frequency:
Every 2 hours
Estimated price:
$101.26–$189.87
Train from Lugano to Milano
Ave. Duration:
1h 15m
Frequency:
Hourly
Estimated price:
$27.85–$49.37
Train from Basel SBB to Zürich
Ave. Duration:
1h 12m
Frequency:
Every 20 minutes
Estimated price:
$41.77–$75.95
Train from Zürich HB to Milan
Ave. Duration:
3h 40m
Frequency:
Once daily
Estimated price:
$88.60–$164.55
Train from Singen to Zürich
Ave. Duration:
51 min
Frequency:
Hourly
Estimated price:
$32.91–$60.76
Train from Zürich HB to Genova
Ave. Duration:
6h 37m
Frequency:
Once daily
Estimated price:
$164.55–$291.13

SBB GmbH

Phone:
+49 (0) 7531 915109
Website:
sbb-deutschland.de/
Train from Basel SBB to Lugano
Ave. Duration:
3h 22m
Frequency:
Once daily
Estimated price:
$24.05–$30.38

DB ZugBus Regionalverkehr Alb-Bodensee GmbH (RAB)

Phone:
+49 731 1550-0
Website:
meine-rab.de/
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
1h 10m
Frequency:
Once a week
Estimated price:
$13.92–$18.99
Train from Hauptbahnhof to Ulm
Ave. Duration:
1h 4m
Frequency:
Hourly
Estimated price:
$15.19–$20.25

Nebenbahn Vaihingen- Enzweihlingen

Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
1h 10m
Frequency:
Once a week
Train from Hauptbahnhof to Ulm
Ave. Duration:
1h 21m
Frequency:
Twice a week

Go Ahead BW

Phone:
+49 711 400 534 44
Website:
go-ahead-bw.de/
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
1h 7m
Frequency:
Hourly
Estimated price:
$17.72–$32.91
Train from Hauptbahnhof to Ulm
Ave. Duration:
1h 38m
Frequency:
Hourly
Estimated price:
$18.99–$35.44

Südwestdeutsche Landesverkehrs-GmbH (SWEG)

Phone:
+49 7821 9960770
Website:
sweg.de/
Train from Karlsruhe Hauptbahnhof to Hauptbahnhof
Ave. Duration:
1h 36m
Frequency:
5 times a week

Süwex

Phone:
0621 8301200
Website:
suewex.de/
Train from Karlsruhe Hauptbahnhof to Mainz,
Ave. Duration:
1h 41m
Frequency:
Every 4 hours
Estimated price:
$26.58–$37.97

Other operators

Grandi Navi Veloci

Phone:
+39 010 209 4591
Website:
gnv.it/en
Other from Port of Genoa to Port
Ave. Duration:
20h 45m
Frequency:
Once daily
Estimated price:
$88.60–$202.52

Questions and Answers

What is the cheapest way to get from Karlsruhe to Palermo?

The cheapest way to get from Karlsruhe to Palermo is to bus and bus and ferry which costs $81.52 - $163.04 and takes 33h 10m.

What is the fastest way to get from Karlsruhe to Palermo?

The fastest way to get from Karlsruhe to Palermo is to bus and fly which takes 6h 7m and costs $65.22 - $260.87 .

Is there a direct bus between Karlsruhe and Palermo?

No, there is no direct bus from Karlsruhe station to Palermo. However, there are services departing from Karlsruhe central train station and arriving at Palermo Terminal Bus via Bologna Pzza xx Settembre. The journey, including transfers, takes approximately 30h 30m.

Is there a direct train between Karlsruhe and Palermo?

No, there is no direct train from Karlsruhe to Palermo. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Palermo Centrale via Basel SBB, Lugano, Milan Centrale and Roma Termini. The journey, including transfers, takes approximately 23h 44m.

How far is it from Karlsruhe to Palermo?

The distance between Karlsruhe and Palermo is 1318 km.

How do I travel from Karlsruhe to Palermo without a car?

The best way to get from Karlsruhe to Palermo without a car is to train which takes 23h 44m and costs $173.91 - $326.09 .

How long does it take to get from Karlsruhe to Palermo?

It takes approximately 6h 7m to get from Karlsruhe to Palermo, including transfers.

Where do I catch the Karlsruhe to Palermo bus from?

Karlsruhe to Palermo bus services, operated by FlixBus, depart from Karlsruhe central train station.

Where do I catch the Karlsruhe to Palermo train from?

Karlsruhe to Palermo train services, operated by Deutsche Bahn Intercity-Express, depart from Karlsruhe Hauptbahnhof station.

Where does the Karlsruhe to Palermo bus arrive?

Karlsruhe to Palermo bus services, operated by FlixBus, arrive at Bologna Centrale station.

Where does the Karlsruhe to Palermo train arrive?

Karlsruhe to Palermo train services, operated by Deutsche Bahn Intercity-Express, arrive at Basel SBB station.

How do I get a train ticket from Karlsruhe to Palermo?

Book your Karlsruhe to Palermo train tickets online with Omio.

Where can I stay near Palermo?

There are 5272+ hotels available in Palermo. Prices start at $37.11 per night.
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