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How to Travel from

Mytilene to Istanbul

by Plane, Route or Car

Mytilene
→
+0 →
Istanbul
Transport search to Istanbul
Simply select points
A and B, and we will create
a convenient route for you 👍
Greece Turkey Mytilene Istanbul
Mytilene
→
+0 →
Istanbul
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
6 h 19 min
433 km.
from $23
Composite Route Car Only
Schedule

Mytilene, Greece → Istanbul, Turkey

All
22 May 2026
May 2026
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December 2026
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All days
23 May, Sat
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27 May, Wed

Cheapest and Fastest Ways to Travel from Mytilene to Istanbul

Composite routes from Mytilene to Istanbul

Cheapest
6 h 19 min
Car
433 km.
from $23
Fastest
1 h 5 min
Plane
Other
10 h 17 min
Ferry, Bus
292 km.
from $70
5 h 24 min
Ferry
292 km.
from $128.70
10 h 31 min
Bus, Train
292 km.
from $54.74

Transport providers

Airlines

Aegean Airlines

Website:
en.aegeanair.com/
Plane from Mytilene International Airport Odysseas Elytis to Istanbul
Ave. Duration:
5h 35m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$114.64–$891.64

Turkish Airlines

Website:
turkishairlines.com/
Plane from Mytilene International Airport Odysseas Elytis to Istanbul
Ave. Duration:
5h 38m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$114.64–$891.64

Train operators

Turkish Railways (TCDD)

Phone:
+90 444 8 233
Email:
Website:
tcdd.gov.tr/
Train from Gebze to Yenikapi
Ave. Duration:
1h 16m
Frequency:
Every 15 minutes
Estimated price:
$2.17–$3.06

Bus operators

Kamil Koc

Phone:
444 0 562
Email:
Website:
flixbus.com
Bus from Edremit bus station to İstanbul
Ave. Duration:
7h 25m
Frequency:
Twice daily
Estimated price:
$12.74–$19.11

Pamukkale

Phone:
0 850 333 35 35
Email:
Website:
pamukkale.com.tr
Bus from Ayvalık to Edremit
Ave. Duration:
1h
Frequency:
3 times a day
Estimated price:
$6.11–$8.92
Bus from Ayvalık to Bursa
Ave. Duration:
4h 30m
Frequency:
3 times a day
Estimated price:
$10.83–$15.29

Metro Turizm

Phone:
0850 222 34 55
Email:
Website:
metroturizm.com.tr/en
Bus from Ayvalik to Istanbul
Ave. Duration:
8h 2m
Frequency:
3 times a day
Estimated price:
$15.29–$21.65
Bus from Ayvalık to Edremit
Ave. Duration:
47 min
Frequency:
Twice daily
Estimated price:
$8.28–$12.10
Bus from Bursa to Gebze
Ave. Duration:
1h 17m
Frequency:
Once daily
Estimated price:
$8.92–$14.01

Other operators

Makri Travel

Phone:
+30 694 415 6070
Email:
Website:
makritravel.com/tr/
Other from Mytilene to Port
Ave. Duration:
1h 15m
Frequency:
Once daily
Estimated price:
$37.28

Jalem Tur

Phone:
0545 783 50 61
Email:
Website:
jalemtur.com/
Other from Mytilene to Port
Ave. Duration:
1h 30m
Frequency:
Once daily
Estimated price:
$31.08

Questions and Answers

What is the cheapest way to get from Mytilene to Istanbul?

The cheapest way to get from Mytilene to Istanbul is to ferry and bus which costs $44.57 - $51.09 and takes 10h 17m.

What is the fastest way to get from Mytilene to Istanbul?

The fastest way to get from Mytilene to Istanbul is to fly which takes 5h 8m and costs $108.70 - $413.04 .

How far is it from Mytilene to Istanbul?

The distance between Mytilene and Istanbul is 356 km.

How do I travel from Mytilene to Istanbul without a car?

The best way to get from Mytilene to Istanbul without a car is to ferry and bus which takes 10h 17m and costs $44.57 - $51.09 .

How long does it take to get from Mytilene to Istanbul?

It takes approximately 5h 8m to get from Mytilene to Istanbul, including transfers.

What is the time difference between Mytilene and Istanbul?

Istanbul is 1h ahead of Mytilene. It is currently 06:31 in Mytilene and 07:31 in Istanbul.

Where can I stay near Istanbul?

There are 4660+ hotels available in Istanbul. Prices start at $22.90 per night.
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