HUB hero image

How to Travel from

Antigua Guatemala to Santa Ana

by Train, Route or Car

Antigua Guatemala
+0
Santa Ana
Transport search to Santa Ana
Antigua Guatemala
+0
Santa Ana
Building a composite car route
Cheapest
Best Offer!
Car
2 d
4378 km.
from $240
Composite Route Car Only
Schedule

Antigua Guatemala, Guatemala → Santa Ana, United States of America

All
21 Mar 2026
March 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
23
24
25
26
27
28
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
April 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
May 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
June 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
July 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
August 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
September 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
October 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
November 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
6
December 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
January 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
February 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
All days
22 Mar, Sun
23 Mar, Mon
24 Mar, Tue
25 Mar, Wed
26 Mar, Thu

Six ways to Travel from Antigua Guatemala to Santa Ana

Composite routes from Antigua Guatemala to Santa Ana

Cheapest
Other

Transport providers

Airlines

Avianca - Aerovías del Continente Americano S.A.

Website:
avianca.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 32m
Frequency:
Every day
Estimated price:
$121.01–$522.25
Plane from La Aurora International Airport to San
Ave. Duration:
12h 8m
Frequency:
Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
Estimated price:
$178.33–$560.46
Plane from La Aurora International Airport to Ontario
Ave. Duration:
12h 30m
Frequency:
Tuesday, Thursday, and Saturday
Estimated price:
$152.85–$471.30
Plane from El Salvador International Airport to Los
Ave. Duration:
5h 40m
Frequency:
Every day
Estimated price:
$121.01–$292.97

American Airlines

Website:
aa.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 52m
Frequency:
Every day
Estimated price:
$178.33–$534.99
Plane from La Aurora International Airport to John
Ave. Duration:
9h 20m
Frequency:
Every day
Estimated price:
$216.54–$955.33
Plane from La Aurora International Airport to San
Ave. Duration:
8h 36m
Frequency:
Every day
Estimated price:
$216.54–$955.33
Plane from La Aurora International Airport to Ontario
Ave. Duration:
9h 56m
Frequency:
Every day
Estimated price:
$165.59–$764.27
Plane from El Salvador International Airport to Los
Ave. Duration:
9h 13m
Frequency:
Every day
Estimated price:
$165.59–$471.30

Delta

Website:
delta.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 34m
Frequency:
Monday, Tuesday, Wednesday, Friday, and Saturday
Estimated price:
$191.07–$305.71
Plane from La Aurora International Airport to John
Ave. Duration:
10h 25m
Frequency:
Monday, Thursday, Friday, and Sunday
Estimated price:
$343.92–$471.30
Plane from La Aurora International Airport to San
Ave. Duration:
10h 59m
Frequency:
Monday, Tuesday, Wednesday, Friday, and Saturday
Estimated price:
$242.02–$394.87
Plane from La Aurora International Airport to Ontario
Ave. Duration:
9h 34m
Frequency:
Saturday
Estimated price:
$267.49–$369.40
Plane from El Salvador International Airport to Los
Ave. Duration:
5h 50m
Frequency:
Tuesday, Thursday, Friday, and Sunday
Estimated price:
$229.28–$369.40

United Airlines

Website:
united.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 24m
Frequency:
Every day
Estimated price:
$152.85–$955.33
Plane from La Aurora International Airport to John
Ave. Duration:
10h
Frequency:
Every day
Estimated price:
$229.28–$891.64
Plane from La Aurora International Airport to San
Ave. Duration:
9h 26m
Frequency:
Every day
Estimated price:
$229.28–$827.95
Plane from La Aurora International Airport to Ontario
Ave. Duration:
11h 23m
Frequency:
Every day
Estimated price:
$178.33–$700.58
Plane from El Salvador International Airport to Los
Ave. Duration:
5h 31m
Frequency:
Every day
Estimated price:
$165.59–$891.64

Frontier Airlines

Website:
flyfrontier.com/
Plane from La Aurora International Airport to Ontario
Ave. Duration:
8h 43m
Frequency:
Every day
Estimated price:
$82.80–$343.92

Alaska Airlines, Inc.

Website:
alaskaair.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 52m
Frequency:
Every day
Estimated price:
$178.33–$534.99

Aeroméxico

Website:
aeromexico.com/es-mx
Plane from La Aurora International Airport to Los
Ave. Duration:
9h 12m
Frequency:
Every day
Estimated price:
$229.28–$573.20
Plane from Tapachula International Airport to General
Ave. Duration:
7h 42m
Frequency:
Every day
Estimated price:
$254.76–$1,528.53
Plane from El Salvador International Airport to Los
Ave. Duration:
8h 48m
Frequency:
Every day
Estimated price:
$369.40–$3,057.06

Volaris

Website:
volaris.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
8h 56m
Frequency:
Thursday, Saturday, and Sunday
Estimated price:
$191.07–$509.51
Plane from Tapachula International Airport to General
Ave. Duration:
4h 42m
Frequency:
Monday, Tuesday, Wednesday, Friday, and Sunday
Estimated price:
$203.80–$1,019.02

Volaris El Salvador

Website:
volaris.com/
Plane from El Salvador International Airport to Los
Ave. Duration:
5h 35m
Frequency:
Every day
Estimated price:
$165.59–$471.30

Volaris Costa Rica

Website:
volaris.com/
Plane from La Aurora International Airport to Los
Ave. Duration:
5h 21m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$152.85–$764.27

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from San Diego Old Town Transportation Center to Santa
Ave. Duration:
1h 49m
Frequency:
Every 3 hours
Estimated price:
$14.01–$89.16
Train from San Diego to Santa
Ave. Duration:
1h 58m
Frequency:
Every 3 hours
Estimated price:
$14.01–$89.16
Train from San Marcos Amtrak to Los
Ave. Duration:
36h 2m
Frequency:
3 times a week
Estimated price:
$140.12–$471.30
Train from Los Angeles to Santa
Ave. Duration:
50 min
Frequency:
Every 3 hours
Estimated price:
$7.01–$76.43

Metrolink Trains

Phone:
(800) 371-LINK (5465)
Website:
metrolinktrains.com
Train from Rancho Cucamonga station to L.
Ave. Duration:
1h 16m
Frequency:
Hourly
Estimated price:
$10.19–$12.74
Train from L. A. Union Station station to Santa
Ave. Duration:
55 min
Frequency:
Every 3 hours
Estimated price:
$4.71–$5.86

Bus operators

ADO

Phone:
+52 55 4386 4652
Website:
ado.com.mx/
Bus from Tapachula to Terminal
Ave. Duration:
21h 50m
Frequency:
Twice daily
Estimated price:
$101.90–$152.85

Greyhound USA

Phone:
+1 214-849-8100
Website:
greyhound.com/
Bus from Tijuana - Plaza El Mexicano to Santa
Ave. Duration:
4h 20m
Frequency:
4 times a day
Estimated price:
$8.92–$95.53

OMEX VIP

Phone:
+52 800 765 6636
Website:
omexvip.com.mx/index.php
Bus from Terminal Central de Autobuses del Norte to San
Ave. Duration:
21h 16m
Frequency:
Once daily
Estimated price:
$127.38–$216.54

Ómnibus Cristóbal Colón (OCC)

Phone:
+52 55 4386 4652
Website:
ado.com.mx/
Bus from Tapachula to Terminal
Ave. Duration:
18h 5m
Frequency:
3 times a day
Estimated price:
$89.16–$191.07

Omnibus de Mexico

Phone:
+52 55 5141 4300
Website:
odm.com.mx/
Bus from Terminal Central de Autobuses del Norte to Tijuana
Ave. Duration:
43h 20m
Frequency:
Every 4 hours
Estimated price:
$165.59–$305.71

Autobuses Elite

Phone:
+52 55 4440 3187
Website:
autobuseselite.com.mx/
Bus from Terminal Central de Autobuses del Norte to Tijuana
Ave. Duration:
41h 40m
Frequency:
Every 3 hours
Estimated price:
$152.85–$229.28

Autotravel

Phone:
+52 713 120 0700
Website:
autotravel.mx/
Bus from Tapachula to Culiacán
Ave. Duration:
44h 50m
Frequency:
5 times a week
Estimated price:
$82.80–$114.64

Transportes Starbus

Phone:
+502 2471 0952
Website:
mmcorporacion.com/?page_id=496
Bus from Guatemala City to San
Ave. Duration:
3h
Frequency:
3 times a day
Estimated price:
$15.29–$35.67

ACN Autobuses

Phone:
+52 664 299 0487
Website:
acnautobuses.com/
Bus from Ciudad de México Politécnico to Tepic
Ave. Duration:
8h 20m
Frequency:
Once daily
Estimated price:
$26.75–$63.69
Bus from Tepic to Santa
Ave. Duration:
27h 30m
Frequency:
Once daily
Estimated price:
$89.16–$178.33
Bus from Culiacán to Santa
Ave. Duration:
20h 30m
Frequency:
Once daily
Estimated price:
$63.69–$140.12

Ecobus Express

Phone:
+52 55 5526 2961
Website:
facebook.com/ecobusexpres/
Bus from Tapachula to Mexico
Ave. Duration:
16h 15m
Frequency:
Once daily
Estimated price:
$36.94–$52.22

Travel To Guatemala Shuttle

Phone:
+502 4021 1921
Website:
aviajarguatemala.webnode.es/
Bus from Antigua Guatemala to Tapachula
Ave. Duration:
3h 30m
Frequency:
5 times a week
Estimated price:
$26.75–$89.16

Greyhound Mexico

Phone:
+01-800-890-6821
Website:
greyhound.com.mx
Bus from Tijuana - Plaza El Mexicano to Santa
Ave. Duration:
4h 20m
Frequency:
4 times a day
Estimated price:
$19.11–$49.68

El Condor Internacional

Phone:
+???????????? ???????????????? ????????????????
Website:
facebook.com/Elcondorinter/
Bus from Escuintla to Tapachula
Ave. Duration:
6h 10m
Frequency:
Once daily

Autobuses Titanium

Phone:
+52 961 638 5018
Website:
autobusestitanium.com/
Bus from Tapachula to Politécnico
Ave. Duration:
15h 45m
Frequency:
Once daily
Estimated price:
$53.50–$76.43

Infini Tours

Phone:
+503 7223 2638
Website:
infinitours.co/
Bus from Guatemala City to El
Ave. Duration:
2h 30m
Frequency:
On demand

Transporte Rapidos Del Sur

Phone:
+502 2232 2771 / 7924 8072
Website:
facebook.com/p/Transporte-Rapidos-Del-Sur-100057169939973/
Bus from Escuintla to Pajapita
Ave. Duration:
3h 34m
Frequency:
4 times a day
Estimated price:
$12.71

Questions and Answers

What is the cheapest way to get from Antigua Guatemala to Santa Ana?

The cheapest way to get from Antigua Guatemala to Santa Ana is to fly which costs $108.70 - $250 and takes 11h 31m.

What is the fastest way to get from Antigua Guatemala to Santa Ana?

The fastest way to get from Antigua Guatemala to Santa Ana is to fly which takes 11h 31m and costs $108.70 - $250 .

Is there a direct bus between Antigua Guatemala and Santa Ana?

No, there is no direct bus from Antigua Guatemala to Santa Ana. However, there are services departing from Antigua Guatemala and arriving at Santa Ana via Escuintla, Tapachula, Ciudad de México Politécnico and Tepic. The journey, including transfers, takes approximately 2 days 15h.

How far is it from Antigua Guatemala to Santa Ana?

The distance between Antigua Guatemala and Santa Ana is 3637 km. The road distance is 4371.3 km.

How do I travel from Antigua Guatemala to Santa Ana without a car?

The best way to get from Antigua Guatemala to Santa Ana without a car is to bus via Mexico City which takes 2 days 15h and costs .

How long does it take to get from Antigua Guatemala to Santa Ana?

It takes approximately 11h 31m to get from Antigua Guatemala to Santa Ana, including transfers.

Where do I catch the Antigua Guatemala to Santa Ana bus from?

Antigua Guatemala to Santa Ana bus services, operated by El Condor Internacional, depart from Escuintla station.

Bus or fly from Antigua Guatemala to Santa Ana?

The best way to get from Antigua Guatemala to Santa Ana is to fly which takes 11h 31m and costs $108.70 - $250 . Alternatively, you can bus via Mexico City, which costs and takes 2 days 15h.

Where does the Antigua Guatemala to Santa Ana bus arrive?

Antigua Guatemala to Santa Ana bus services, operated by El Condor Internacional, arrive at Tapachula station.

What is the time difference between Antigua Guatemala and Santa Ana?

Santa Ana is 1h behind Antigua Guatemala. It is currently 12:47 in Antigua Guatemala and 11:47 in Santa Ana.

Can I drive from Antigua Guatemala to Santa Ana?

Yes, the driving distance between Antigua Guatemala to Santa Ana is 4371 km. It takes approximately 47h 55m to drive from Antigua Guatemala to Santa Ana.

Where can I stay near Santa Ana?

There are 1146+ hotels available in Santa Ana. Prices start at $57.07 per night.
+0