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How to Travel from

Syracuse to Prague

by Plane, Route or Car

Syracuse
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Prague
Transport search to Prague
Syracuse
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Prague
Building a composite car route
Cheapest
Best Offer!
Car
21 h 21 min
2048 km.
from $112
Composite Route Car Only
Schedule

Syracuse, Italy → Prague, Czech

All
01 Jul 2026
July 2026
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January 2027
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All days
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Cheapest and Fastest Ways to Travel from Syracuse to Prague

Composite routes from Syracuse to Prague

Cheapest
Other

Transport providers

Ryanair
Website
Lufthansa
Website
Ulendo Airlink
Website
Smartwings
Website
Ryanair
Website
2h 30m
Wednesday, Friday, and Sunday
$54.35–$456.52
Lufthansa
Website
4h 10m
Friday to Sunday
$250.00–$815.22
Ulendo Airlink
Website
2h 35m
Tuesday and Saturday
$59.78–$326.09
Smartwings
Website
2h 25m
Wednesday and Sunday
$130.43–$304.35
FlixBus
Website
Busitalia Simet S.p.A.
Website
Azienda Siciliana Trasporti
Website
SAIS trasporti S.p.A. - Autolinee Giamporcaro
Website
Interbus
Website
FlixBus
Website
15h 40m
Once daily
$92.39–$130.43
+49 30 300 137 300
+49 30 300 137 300
Call Contact via email
Busitalia Simet S.p.A.
Website
18h 50m
Once a week
$119.57–$141.30
+39 098 3520 315
+39 098 3520 315
Call Contact via email
Azienda Siciliana Trasporti
Website
1h 30m
6 times a week
+39 091 62.08.111
+39 091 62.08.111
Call Contact via email
SAIS trasporti S.p.A. - Autolinee Giamporcaro
Website
5h 30m
Twice daily
$26.09–$33.70
+39 0912742800
+39 0912742800
Call Contact via email
Interbus
Website
1h 19m
Hourly
$5.43–$8.15
+39 0935 22 460
+39 0935 22 460
Call Contact via email
Deutsche Bahn Intercity-Express
Website
WESTbahn Gmbh
Website
Railjet
Website
ÖBB
Website
Nightjet
Website
ÖBB EuroCity
Website
Trenitalia
Website
Trenitalia Frecce
Website
ItaloTreno
Website
Trenitalia Intercity
Website
RegioJet
Website
Die Länderbahn
Website
Trenitalia Intercity Night
Website
Deutsche Bahn Intercity-Express
Website
1h 12m
4 times a day
$30.43–$33.70
+49 30 311-682904
+49 30 311-682904
Call
WESTbahn Gmbh
Website
3h 8m
5 times a day
$41.30–$97.83
+43 1 89900
+43 1 89900
Call Contact via email
Railjet
Website
1h 20m
Once daily
$18.48–$27.17
+43 51717
+43 51717
Call
ÖBB
Website
1h 20m
Twice daily
$17.39–$23.91
05 17 17
05 17 17
Call
Nightjet
Website
8h 41m
Once daily
$54.35–$173.91
+43 51717
+43 51717
Call
ÖBB EuroCity
Website
3h 45m
4 times a day
$47.83–$70.65
+43 5 1717
+43 5 1717
Call
Trenitalia
Website
1h 7m
Every 2 hours
$5.98–$15.22
+39 06 68475475
+39 06 68475475
Call
Trenitalia Frecce
Website
4h 58m
Every 4 hours
$45.65–$141.30
+39 06 68475475
+39 06 68475475
Call
ItaloTreno
Website
4h 58m
Twice daily
$81.52–$108.70
+39 06 8937 1892
+39 06 8937 1892
Call
Trenitalia Intercity
Website
11h 9m
Once daily
$51.09–$70.65
+39 06 68475475
+39 06 68475475
Call
RegioJet
Website
14h 35m
Once a week
$59.78–$92.39
+420 222 222 221
+420 222 222 221
Call Contact via email
Die Länderbahn
Website
5h 38m
Every 4 hours
0 89 54 888 97 - 25
0 89 54 888 97 - 25
Call Contact via email
Trenitalia Intercity Night
Website
17h 32m
Once daily
$92.39–$130.43
06 3000
06 3000
Call
Blu Jet
Website
Blu Jet
Website
20 min
Hourly
$2.64–$2.65
342 32 55 869
342 32 55 869
Call

Questions and Answers

What is the cheapest way to get from Syracuse to Prague?

The cheapest way to get from Syracuse to Prague is to train and fly which costs $47.83 - $282.61 and takes 6h 12m.

What is the fastest way to get from Syracuse to Prague?

The fastest way to get from Syracuse to Prague is to train and fly which takes 6h 12m and costs $47.83 - $282.61 .

Is there a direct bus between Syracuse and Prague?

No, there is no direct bus from Syracuse to Prague. However, there are services departing from Siracusa - Von Platen and arriving at Praha, ÚAN Florenc via Catania and Bologna Centrale. The journey, including transfers, takes approximately 32h 24m.

Is there a direct train between Syracuse and Prague?

No, there is no direct train from Syracuse to Prague. However, there are services departing from Siracusa and arriving at Praha Hlavni Nadrazi via Roma Termini, Bolzano Bozen, Brennero Brenner, Innsbruck Hbf and Linz Hbf. The journey, including transfers, takes approximately 28h 15m.

How far is it from Syracuse to Prague?

The distance between Syracuse and Prague is 1500 km.

How do I travel from Syracuse to Prague without a car?

The best way to get from Syracuse to Prague without a car is to train which takes 28h 15m and costs $195.65 - $445.65 .

How long does it take to get from Syracuse to Prague?

It takes approximately 6h 12m to get from Syracuse to Prague, including transfers.

Where do I catch the Syracuse to Prague bus from?

Syracuse to Prague bus services, operated by Interbus, depart from Siracusa - Von Platen station.

Where do I catch the Syracuse to Prague train from?

Syracuse to Prague train services, operated by Trenitalia Intercity, depart from Siracusa station.

Train or bus from Syracuse to Prague?

The best way to get from Syracuse to Prague is to train which takes 28h 15m and costs $195.65 - $445.65 . Alternatively, you can bus, which costs $152.17 - $250 and takes 32h 24m.

Where does the Syracuse to Prague bus arrive?

Syracuse to Prague bus services, operated by Interbus, arrive at Catania Via Archimede station.

Where does the Syracuse to Prague train arrive?

Syracuse to Prague train services, operated by Trenitalia Intercity, arrive at Roma Termini station.

How do I get a train ticket from Syracuse to Prague?

Book your Syracuse to Prague train tickets online with Omio.

How do I get a bus ticket from Syracuse to Prague?

Book your Syracuse to Prague bus tickets online with Omio.

Where can I stay near Prague?

There are 3498+ hotels available in Prague. Prices start at $26.51 per night.
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