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How to Travel from

Palermo to Mainz

by Plane, Route or Car

Palermo
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Mainz
Transport search to Mainz
Palermo
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Mainz
Building a composite car route
Cheapest
Best Offer!
Car
27 h 43 min
1781 km.
from $97
Composite Route Car Only
Schedule

Palermo, Italy → Mainz, Germany

All
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July 2026
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Cheapest and Fastest Ways to Travel from Palermo to Mainz

Composite routes from Palermo to Mainz

Cheapest
Fastest
Other

Transport providers

Ryanair
Website
Lufthansa
Website
Eurowings
Website
Swiss
Website
Alitalia
Website
Ryanair
Website
2h 20m
Monday and Saturday
$40.65–$215.96
Lufthansa
Website
2h 25m
Thursday and Saturday
$304.89–$952.78
Eurowings
Website
2h 25m
Tuesday
$114.33–$343.00
Swiss
Website
4h 25m
Monday, Friday, and Sunday
$69.87–$431.92
Alitalia
Website
5h
Monday to Friday
$139.74–$355.70
FlixBus
Website
Flibco
Website
Autoservizi Salemi Srl
Website
SAIS Autolinee
Website
Busitalia Simet S.p.A.
Website
Satam Bus
Website
FlixBus
Website
11h 25m
Once daily
$69.87–$101.63
+49 30 300 137 300
+49 30 300 137 300
Call Contact via email
Flibco
Website
1h 15m
Every 2 hours
$13.97–$21.60
+352 26 58 57 1
+352 26 58 57 1
Call Contact via email
Autoservizi Salemi Srl
Website
19h 50m
Once daily
$41.92–$107.98
(+39) 0923 98.11.20
(+39) 0923 98.11.20
Call
SAIS Autolinee
Website
2h 25m
Hourly
$13.97–$20.33
800 21 10 20
800 21 10 20
Call Contact via email
Busitalia Simet S.p.A.
Website
14h 50m
Once a week
$114.33–$139.74
+39 098 3520 315
+39 098 3520 315
Call Contact via email
Satam Bus
Website
3h 50m
4 times a day
$22.87–$33.03
+39 0871 344969
+39 0871 344969
Call Contact via email
NS
Website
Deutsche Bahn Intercity-Express
Website
Deutsche Bahn Regional
Website
Trenitalia
Website
Trenitalia Frecce
Website
ItaloTreno
Website
Trenitalia Intercity
Website
Trenitalia EuroCity
Website
Süwex
Website
NS
Website
42 min
3 times a day
$21.60–$53.36
+31 30 751 5155
+31 30 751 5155
Call
Deutsche Bahn Intercity-Express
Website
39 min
Every 4 hours
$31.76–$36.84
+49 30 311-682904
+49 30 311-682904
Call
Deutsche Bahn Regional
Website
1h 24m
Hourly
$16.51–$24.14
+49 30 2970
+49 30 2970
Call
Trenitalia
Website
2h 44m
Every 4 hours
$15.24–$50.81
+39 06 68475475
+39 06 68475475
Call
Trenitalia Frecce
Website
8h 17m
5 times a day
$95.28–$279.48
+39 06 68475475
+39 06 68475475
Call
ItaloTreno
Website
9h 55m
5 times a day
$165.15–$228.67
+39 06 8937 1892
+39 06 8937 1892
Call
Trenitalia Intercity
Website
2h 50m
Twice daily
$17.79–$25.41
+39 06 68475475
+39 06 68475475
Call
Trenitalia EuroCity
Website
6h 48m
Once daily
$152.44–$228.67
+39 06 68475475
+39 06 68475475
Call Contact via email
Süwex
Website
52 min
Every 4 hours
$17.79–$25.41
0621 8301200
0621 8301200
Call
Grandi Navi Veloci
Website
Blu Jet
Website
Tirrenia
Website
Grandi Navi Veloci
Website
20h 45m
Once daily
$88.93–$203.26
+39 010 209 4591
+39 010 209 4591
Call Contact via email
Blu Jet
Website
20 min
Hourly
$3.09–$3.10
342 32 55 869
342 32 55 869
Call
Tirrenia
Website
10h 30m
Once daily
$52.09–$82.57
02 76028132
02 76028132
Call Contact via email

Questions and Answers

What is the cheapest way to get from Palermo to Mainz?

The cheapest way to get from Palermo to Mainz is to fly and bus which costs $50 - $217.39 and takes 7h 19m.

What is the fastest way to get from Palermo to Mainz?

The fastest way to get from Palermo to Mainz is to fly which takes 5h 43m and costs $130.43 - $282.61 .

Is there a direct bus between Palermo and Mainz?

No, there is no direct bus from Palermo to Mainz station. However, there are services departing from Palermo Terminal Bus and arriving at Mainz central train station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 32h 15m.

Is there a direct train between Palermo and Mainz?

No, there is no direct train from Palermo to Mainz. However, there are services departing from Palermo Centrale and arriving at Mainz, Hauptbahnhof via Roma Termini, Milan Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 23h 30m.

How far is it from Palermo to Mainz?

The distance between Palermo and Mainz is 1425 km.

How do I travel from Palermo to Mainz without a car?

The best way to get from Palermo to Mainz without a car is to train and ferry which takes 21h 32m and costs $228.26 - $521.74 .

How long does it take to get from Palermo to Mainz?

It takes approximately 5h 43m to get from Palermo to Mainz, including transfers.

Where do I catch the Palermo to Mainz bus from?

Palermo to Mainz bus services, operated by Autoservizi Salemi Srl, depart from Palermo Terminal Bus station.

Where do I catch the Palermo to Mainz train from?

Palermo to Mainz train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.

Train or fly from Palermo to Mainz?

The best way to get from Palermo to Mainz is to fly which takes 5h 43m and costs $130.43 - $282.61 . Alternatively, you can train, which costs $239.13 - $434.78 and takes 23h 30m.

Where does the Palermo to Mainz bus arrive?

Palermo to Mainz bus services, operated by Autoservizi Salemi Srl, arrive at Milano, Autostazione Lampugnano station.

Where does the Palermo to Mainz train arrive?

Palermo to Mainz train services, operated by Trenitalia Intercity, arrive at Roma Termini station.

How do I get a train ticket from Palermo to Mainz?

Book your Palermo to Mainz train tickets online with Omio.

Where can I stay near Mainz?

There are 961+ hotels available in Mainz. Prices start at $47.72 per night.
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