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How to Travel from

Como to Isernia

by Plane, Route or Car

Como
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Isernia
Transport search to Isernia
Como
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Isernia
Building a composite car route
Cheapest
Best Offer!
Car
7 h 39 min
757 km.
from $41
Composite Route Car Only
Schedule

Como, Italy → Isernia, Italy

All
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July 2026
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Cheapest and Fastest Ways to Travel from Como to Isernia

Composite routes from Como to Isernia

Cheapest
Other

Transport providers

Ryanair
Website
easyJet
Website
Alitalia
Website
FlexFlight ApS
Website
Aeroitalia
Website
Bristow
Website
Ryanair
Website
1h 25m
Every day
$29.22–$444.65
easyJet
Website
1h 30m
Every day
$39.38–$279.49
Alitalia
Website
1h 20m
Every day
$54.63–$292.20
FlexFlight ApS
Website
3h 5m
Every day
$152.45–$381.13
Aeroitalia
Website
3h 5m
Every day
$152.45–$381.13
Bristow
Website
1h 25m
Every day
$36.84–$343.02
FlixBus
Website
Flibco
Website
TerraVision IT
Website
Autostradale
Website
Gruppo Di Maio
Website
Società Autocooperative Trasporti Italiani S.p.A.
Website
ATM Azienda di Trasporti Molisana S.p.A.
Website
FlixBus
Website
6h 5m
Twice daily
$35.57–$49.55
+49 30 300 137 300
+49 30 300 137 300
Call Contact via email
Flibco
Website
50 min
Every 30 minutes
$10.16–$15.25
+352 26 58 57 1
+352 26 58 57 1
Call Contact via email
TerraVision IT
Website
50 min
Every 30 minutes
$7.62–$12.07
Autostradale
Website
1h
Every 30 minutes
$5.08–$19.06
+39 02 3008 9000
+39 02 3008 9000
Call Contact via email
Gruppo Di Maio
Website
10h
Twice a week
$69.87–$107.99
+39 0827 34 117
+39 0827 34 117
Call Contact via email
Società Autocooperative Trasporti Italiani S.p.A.
Website
55 min
3 times a day
$2.41–$2.92
0865.221788
0865.221788
Call Contact via email
ATM Azienda di Trasporti Molisana S.p.A.
Website
2h 15m
Twice daily
$10.16–$15.25
+39 0874 64744
+39 0874 64744
Call Contact via email
Deutsche Bahn Intercity-Express
Website
Trenitalia
Website
Trenitalia Frecce
Website
ItaloTreno
Website
Trenitalia Intercity
Website
Swiss Railways (SBB/CFF/FFS)
Website
Trenitalia EuroCity
Website
Deutsche Bahn Intercity-Express
Website
40 min
Once daily
$27.95–$31.76
+49 30 311-682904
+49 30 311-682904
Call
Trenitalia
Website
2h 12m
5 times a day
$12.70–$41.92
+39 06 68475475
+39 06 68475475
Call
Trenitalia Frecce
Website
3h 12m
Every 30 minutes
$48.28–$152.45
+39 06 68475475
+39 06 68475475
Call
ItaloTreno
Website
3h 39m
Hourly
$48.24–$120.69
+39 06 8937 1892
+39 06 8937 1892
Call
Trenitalia Intercity
Website
7h 12m
Once daily
$40.65–$55.90
+39 06 68475475
+39 06 68475475
Call
Swiss Railways (SBB/CFF/FFS)
Website
41 min
Hourly
$26.68–$47.01
+41 848 44 66 88
+41 848 44 66 88
Call
Trenitalia EuroCity
Website
40 min
6 times a week
$21.60–$76.23
+39 06 68475475
+39 06 68475475
Call Contact via email

Questions and Answers

What is the cheapest way to get from Como to Isernia?

The cheapest way to get from Como to Isernia is to bus which costs $65.22 - $92.39 and takes 12h 8m.

What is the fastest way to get from Como to Isernia?

The fastest way to get from Como to Isernia is to fly and train which takes 6h 50m and costs $39.13 - $250 .

Is there a direct bus between Como and Isernia?

No, there is no direct bus from Como to Isernia. However, there are services departing from Como Grandate and arriving at Isernia via Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 12h 8m.

Is there a direct train between Como and Isernia?

No, there is no direct train from Como to Isernia. However, there are services departing from Como S. Giovanni and arriving at Isernia via Milan Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 15m.

How far is it from Como to Isernia?

The distance between Como and Isernia is 795 km. The road distance is 775.5 km.

How do I travel from Como to Isernia without a car?

The best way to get from Como to Isernia without a car is to train which takes 7h 15m and costs $59.78 - $228.26 .

How long does it take to get from Como to Isernia?

It takes approximately 7h 15m to get from Como to Isernia, including transfers.

Where do I catch the Como to Isernia bus from?

Como to Isernia bus services, operated by FlixBus, depart from Como station.

Where do I catch the Como to Isernia train from?

Como to Isernia train services, operated by Swiss Railways (SBB/CFF/FFS), depart from Como S. Giovanni station.

Train or bus from Como to Isernia?

The best way to get from Como to Isernia is to train which takes 7h 15m and costs $59.78 - $228.26 . Alternatively, you can bus, which costs $65.22 - $92.39 and takes 12h 8m.

Where does the Como to Isernia bus arrive?

Como to Isernia bus services, operated by FlixBus, arrive at Florence station.

Where does the Como to Isernia train arrive?

Como to Isernia train services, operated by Swiss Railways (SBB/CFF/FFS), arrive at Milano Centrale station.

Can I drive from Como to Isernia?

Yes, the driving distance between Como to Isernia is 776 km. It takes approximately 7h 18m to drive from Como to Isernia.

How do I get a train ticket from Como to Isernia?

Book your Como to Isernia train tickets online with Omio.

How do I get a bus ticket from Como to Isernia?

Book your Como to Isernia bus tickets online with Omio and FlixBus.

Where can I stay near Isernia?

There are 358+ hotels available in Isernia. Prices start at $28.16 per night.
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