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How to Travel from

Isernia to Sicily

by Plane, Route or Car

Isernia
→
+0 →
Sicily
Transport search to Sicily
Simply select points
A and B, and we will create
a convenient route for you 👍
Italy Isernia Sicily
Isernia
→
+0 →
Sicily
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
9 h 36 min
744 km.
from $40
Composite Route Car Only
Schedule

Isernia, Italy → Sicily, Italy

All
02 Jul 2026
July 2026
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August 2026
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January 2027
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February 2027
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May 2027
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June 2027
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All days
03 Jul, Fri
04 Jul, Sat
05 Jul, Sun
06 Jul, Mon
07 Jul, Tue

Cheapest and Fastest Ways to Travel from Isernia to Sicily

Composite routes from Isernia to Sicily

Cheapest
9 h 36 min
Car
744 km.
from $40
Fastest
1 h 24 min
Plane
Other
4 h 29 min
Train, Plane
445 km.
from $103.91
10 h
Ferry
444 km.
from $97.07
12 h 34 min
444 km.
from $74.70
12 h 35 min
444 km.
from $94.30
4 h 59 min
Train, Plane
445 km.
from $95.43
5 h 47 min
Train, Plane
445 km.
from $115
6 h 12 min
Train, Plane
445 km.
from $106.52
5 h 34 min
Train, Plane
445 km.
from $167.72
14 h 32 min
Bus, Ferry
444 km.
from $104.50

Transport providers

Airlines
Found: 8
Ryanair
Website
easyJet
Website
Volotea
Website
Alitalia
Website
FlexFlight ApS
Website
TUI fly Belgium
Website
Condor Flugdienst
Website
Aeroitalia
Website
Ryanair
Website
1h 5m
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
$30.49–$419.24
easyJet
Website
1h 3m
Every day
$33.03–$228.68
Volotea
Website
1h
Monday, Thursday, Friday, and Sunday
$39.38–$279.49
Alitalia
Website
1h 17m
Every day
$50.82–$381.13
FlexFlight ApS
Website
1h 20m
Every day
$17.79–$330.31
TUI fly Belgium
Website
1h 20m
Friday
$44.47–$292.20
Condor Flugdienst
Website
1h 10m
Saturday
$31.76–$152.45
Aeroitalia
Website
1h 20m
Every day
$17.79–$330.31
Bus operators
Found: 2
FlixBus
Website
Autoservizi Salemi Srl
Website
FlixBus
Website
1h 15m
Once daily
$10.80–$15.25
+49 30 300 137 300
+49 30 300 137 300
[email protected]
Call Contact via email
Autoservizi Salemi Srl
Website
9h 45m
Once daily
$38.11–$55.90
(+39) 0923 98.11.20
(+39) 0923 98.11.20
Call
Train operators
Found: 2
Trenitalia
Website
Trenitalia Intercity
Website
Trenitalia
Website
1h 49m
4 times a day
$10.16–$29.22
+39 06 68475475
+39 06 68475475
Call
Trenitalia Intercity
Website
9h 12m
Once daily
$48.28–$69.87
+39 06 68475475
+39 06 68475475
Call
Other operators
Found: 2
Grimaldi Lines
Website
Tirrenia
Website
Grimaldi Lines
Website
8h 30m
Once daily
$43.19–$59.71
+39.081.496.444
+39.081.496.444
[email protected]
Call Contact via email
Tirrenia
Website
10h 30m
Once daily
$52.09–$82.58
02 76028132
02 76028132
[email protected]
Call Contact via email

Questions and Answers

What is the cheapest way to get from Isernia to Sicily?

The cheapest way to get from Isernia to Sicily is to bus which costs $43.48 - $65.22 and takes 12h 34m.

What is the fastest way to get from Isernia to Sicily?

The fastest way to get from Isernia to Sicily is to train and fly which takes 4h 29m and costs $34.78 - $206.52 .

Is there a direct bus between Isernia and Sicily?

No, there is no direct bus from Isernia to Sicily. However, there are services departing from Isernia and arriving at Piazza Boiardo via Caserta Viale Vittorio Veneto and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 12h 34m.

How far is it from Isernia to Sicily?

The distance between Isernia and Sicily is 519 km.

How do I travel from Isernia to Sicily without a car?

The best way to get from Isernia to Sicily without a car is to bus which takes 12h 34m and costs $43.48 - $65.22 .

How long does it take to get from Isernia to Sicily?

It takes approximately 4h 29m to get from Isernia to Sicily, including transfers.

Where do I catch the Isernia to Sicily bus from?

Isernia to Sicily bus services, operated by FlixBus, depart from Isernia station.

Train or bus from Isernia to Sicily?

The best way to get from Isernia to Sicily is to bus which takes 12h 34m and costs $43.48 - $65.22 . Alternatively, you can train, which costs $51.09 - $86.96 and takes 12h 35m.

Where does the Isernia to Sicily bus arrive?

Isernia to Sicily bus services, operated by FlixBus, arrive at Caserta Terminal Bus station.

Where can I stay near Sicily?

There are 230+ hotels available in Sicily. Prices start at $31.18 per night.
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