HUB hero image

How to Travel from

Palermo to Isernia

by Car

Palermo
→
+0 →
Isernia
Transport search to Isernia
Simply select points
A and B, and we will create
a convenient route for you 👍
Italy Palermo Isernia
Palermo
→
+0 →
Isernia
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
16 h
456 km.
from $25
Composite Route Car Only
Schedule

Palermo, Italy → Isernia, Italy

All
03 Jul 2026
July 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
August 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
September 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
October 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
November 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
6
December 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
January 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
February 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
March 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
April 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
May 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
June 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
All days
04 Jul, Sat
05 Jul, Sun
06 Jul, Mon
07 Jul, Tue
08 Jul, Wed

Cheapest and Fastest Ways to Travel from Palermo to Isernia

Composite routes from Palermo to Isernia

Cheapest
16 h
Car
456 km.
from $25

Transport providers

Airlines
Found: 7
Ryanair
Website
easyJet
Website
Volotea
Website
Alitalia
Website
FlexFlight ApS
Website
Condor Flugdienst
Website
Aeroitalia
Website
Ryanair
Website
1h
Monday, Thursday, Friday, Saturday, and Sunday
$34.30–$419.22
easyJet
Website
57 min
Every day
$34.30–$241.37
Volotea
Website
1h
Monday, Thursday, Friday, and Sunday
$39.38–$279.48
Alitalia
Website
1h 10m
Every day
$55.90–$228.67
FlexFlight ApS
Website
1h 10m
Every day
$47.00–$292.18
Condor Flugdienst
Website
1h 25m
Monday, Tuesday, Wednesday, and Sunday
$34.30–$165.15
Aeroitalia
Website
1h 10m
Every day
$47.00–$292.18
Bus operators
Found: 2
FlixBus
Website
Autoservizi Salemi Srl
Website
FlixBus
Website
1h 14m
Once daily
$10.80–$15.24
+49 30 300 137 300
+49 30 300 137 300
[email protected]
Call Contact via email
Autoservizi Salemi Srl
Website
9h 50m
Once daily
$35.57–$54.63
(+39) 0923 98.11.20
(+39) 0923 98.11.20
Call
Train operators
Found: 2
Trenitalia
Website
Trenitalia Intercity
Website
Trenitalia
Website
1h 57m
4 times a day
$10.16–$29.22
+39 06 68475475
+39 06 68475475
Call
Trenitalia Intercity
Website
9h 12m
Once daily
$48.27–$69.87
+39 06 68475475
+39 06 68475475
Call
Other operators
Found: 2
Grimaldi Lines
Website
Tirrenia
Website
Grimaldi Lines
Website
8h 30m
4 times a week
$43.19–$59.71
+39.081.496.444
+39.081.496.444
[email protected]
Call Contact via email
Tirrenia
Website
10h 30m
Once daily
$52.09–$82.57
02 76028132
02 76028132
[email protected]
Call Contact via email

Questions and Answers

What is the cheapest way to get from Palermo to Isernia?

The cheapest way to get from Palermo to Isernia is to bus and ferry and bus which costs $39.13 - $59.78 and takes 12h 4m.

What is the fastest way to get from Palermo to Isernia?

The fastest way to get from Palermo to Isernia is to fly and train which takes 5h 57m and costs $38.04 - $184.78 .

Is there a direct bus between Palermo and Isernia?

No, there is no direct bus from Palermo to Isernia. However, there are services departing from Palermo Terminal Bus and arriving at Isernia via Caserta Terminal Bus. The journey, including transfers, takes approximately 12h 4m.

Is there a direct train between Palermo and Isernia?

No, there is no direct train from Palermo to Isernia. However, there are services departing from Palermo Centrale and arriving at Isernia via Napoli Centrale. The journey, including transfers, takes approximately 12h 9m.

How far is it from Palermo to Isernia?

The distance between Palermo and Isernia is 421 km.

How do I travel from Palermo to Isernia without a car?

The best way to get from Palermo to Isernia without a car is to bus and ferry and bus which takes 12h 4m and costs $39.13 - $59.78 .

How long does it take to get from Palermo to Isernia?

It takes approximately 9h 52m to get from Palermo to Isernia, including transfers.

Where do I catch the Palermo to Isernia bus from?

Palermo to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Palermo Terminal Bus station.

Where do I catch the Palermo to Isernia train from?

Palermo to Isernia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.

Where does the Palermo to Isernia bus arrive?

Palermo to Isernia bus services, operated by Autoservizi Salemi Srl, arrive at Caserta Pzza Garibaldi station.

Where does the Palermo to Isernia train arrive?

Palermo to Isernia train services, operated by Trenitalia Intercity, arrive at Napoli Centrale station.

How do I get a train ticket from Palermo to Isernia?

Book your Palermo to Isernia train tickets online with Omio.

Where can I stay near Isernia?

There are 352+ hotels available in Isernia. Prices start at $28.95 per night.
→
+0 →
Transport search
Transport search