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How to Travel from

Sicily to Isernia

by Plane, Route or Car

Sicily
→
+0 →
Isernia
Transport search to Isernia
Simply select points
A and B, and we will create
a convenient route for you 👍
Italy Sicily Isernia
Sicily
→
+0 →
Isernia
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
8 h 47 min
771 km.
from $42
Composite Route Car Only
Schedule

Sicily, Italy → Isernia, Italy

All
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July 2026
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All days
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09 Jul, Thu
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Cheapest and Fastest Ways to Travel from Sicily to Isernia

Composite routes from Sicily to Isernia

Cheapest
8 h 47 min
Car
771 km.
from $42
Other
5 h 29 min
Bus, Plane
445 km.
from $104.64
5 h 43 min
Bus, Plane
445 km.
from $99.24
9 h 56 min
Ferry
444 km.
from $96.17
13 h 26 min
444 km.
from $95.04
13 h 32 min
444 km.
from $74.50
5 h 57 min
Bus, Plane
445 km.
from $96.25
5 h 24 min
Bus, Plane
445 km.
from $167.50
6 h 25 min
Bus, Plane
445 km.
from $114.64
6 h 48 min
Bus, Plane
445 km.
from $106.25
15 h 17 min
Ferry, Bus
444 km.
from $105.22

Transport providers

Airlines
Found: 7
Ryanair
Website
easyJet
Website
Volotea
Website
Alitalia
Website
FlexFlight ApS
Website
Condor Flugdienst
Website
Aeroitalia
Website
Ryanair
Website
1h 5m
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
$30.49–$419.22
easyJet
Website
1h 6m
Every day
$33.03–$228.67
Volotea
Website
1h
Monday, Thursday, Friday, and Sunday
$39.38–$279.48
Alitalia
Website
1h 25m
Every day
$50.81–$381.11
FlexFlight ApS
Website
1h 15m
Monday, Wednesday, Thursday, Friday, and Sunday
$53.36–$406.52
Condor Flugdienst
Website
1h 25m
Monday, Tuesday, Wednesday, and Sunday
$34.30–$165.15
Aeroitalia
Website
1h 15m
Monday, Wednesday, Thursday, Friday, and Sunday
$53.36–$406.52
Bus operators
Found: 2
FlixBus
Website
Autoservizi Salemi Srl
Website
FlixBus
Website
1h 14m
Once daily
$10.80–$15.24
+49 30 300 137 300
+49 30 300 137 300
[email protected]
Call Contact via email
Autoservizi Salemi Srl
Website
9h 50m
Once daily
$38.11–$55.90
(+39) 0923 98.11.20
(+39) 0923 98.11.20
Call
Train operators
Found: 2
Trenitalia
Website
Trenitalia Intercity
Website
Trenitalia
Website
1h 57m
4 times a day
$10.16–$29.22
+39 06 68475475
+39 06 68475475
Call
Trenitalia Intercity
Website
9h 12m
Once daily
$48.27–$69.87
+39 06 68475475
+39 06 68475475
Call
Other operators
Found: 2
Grimaldi Lines
Website
Tirrenia
Website
Grimaldi Lines
Website
8h 30m
4 times a week
$43.19–$59.71
+39.081.496.444
+39.081.496.444
[email protected]
Call Contact via email
Tirrenia
Website
10h 30m
Once daily
$52.09–$82.57
02 76028132
02 76028132
[email protected]
Call Contact via email

Questions and Answers

What is the cheapest way to get from Sicily to Isernia?

The cheapest way to get from Sicily to Isernia is to bus which costs $42.39 - $65.22 and takes 13h 32m.

What is the fastest way to get from Sicily to Isernia?

The fastest way to get from Sicily to Isernia is to fly and train which takes 5h 24m and costs $76.09 - $315.22 .

Is there a direct bus between Sicily and Isernia?

No, there is no direct bus from Sicily to Isernia. However, there are services departing from Piazza Boiardo and arriving at Isernia via Palermo Via Tommaso Fazello and Caserta Terminal Bus. The journey, including transfers, takes approximately 13h 32m.

Is there a direct train between Sicily and Isernia?

No, there is no direct train from Sicily to Isernia. However, there are services departing from Palermo Notarbartolo and arriving at Isernia via Palermo Centrale and Napoli Centrale. The journey, including transfers, takes approximately 13h 26m.

How far is it from Sicily to Isernia?

The distance between Sicily and Isernia is 520 km.

How do I travel from Sicily to Isernia without a car?

The best way to get from Sicily to Isernia without a car is to train which takes 13h 26m and costs $50 - $92.39 .

How long does it take to get from Sicily to Isernia?

It takes approximately 5h 29m to get from Sicily to Isernia, including transfers.

Where do I catch the Sicily to Isernia bus from?

Sicily to Isernia bus services, operated by Autoservizi Salemi Srl, depart from Palermo Via Tommaso Fazello station.

Where do I catch the Sicily to Isernia train from?

Sicily to Isernia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.

Train or bus from Sicily to Isernia?

The best way to get from Sicily to Isernia is to train which takes 13h 26m and costs $50 - $92.39 . Alternatively, you can bus, which costs $42.39 - $65.22 and takes 13h 32m.

Where does the Sicily to Isernia bus arrive?

Sicily to Isernia bus services, operated by Autoservizi Salemi Srl, arrive at Caserta Viale Vittorio Veneto station.

Where does the Sicily to Isernia train arrive?

Sicily to Isernia train services, operated by Trenitalia Intercity, arrive at Napoli Centrale station.

How do I get a train ticket from Sicily to Isernia?

Book your Sicily to Isernia train tickets online with Omio.

Where can I stay near Isernia?

There are 352+ hotels available in Isernia. Prices start at $28.95 per night.
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