HUB hero image

How to Travel from

Siena to Isernia

by Rideshare, Route or Car

Siena
→
+0 →
Isernia
Transport search to Isernia
Simply select points
A and B, and we will create
a convenient route for you 👍
Italy Siena Isernia
Siena
→
+0 →
Isernia
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
3 h 51 min
385 km.
from $21
Composite Route Car Only

Seven ways to Travel from Siena to Isernia

Select an Option Below to Start Your Journey
Cheapest
By car (385 km)
3 h 51 min
385 km.
from $21
Other
Rideshare
3 h 51 min
385 km.
from $14.65
Bus
5 h 44 min
304 km.
from $7.43
Bus, Train
6 h 12 min
304 km.
from $5.43
Bus, Plane, Train
8 h 51 min
303 km.
Bus via Rome
6 h
304 km.
from $37
Train
7 h 32 min
303 km.
from $70.43

Transport providers

Bus operators

FlixBus

Phone:
+49 30 300 137 300
Email:
Website:
flixbus.com
Bus from Siena to Roma,
Ave. Duration:
2h 50m
Frequency:
Every 2 hours
Estimated price:
$24.14–$34.30
Bus from Roma, Autostazione Tiburtina to Isernia
Ave. Duration:
2h 35m
Frequency:
5 times a week
Estimated price:
$19.06–$27.95

Itabus

Phone:
+39 06 88 93 82 32
Website:
itabus.it/en/home
Bus from Siena to Roma,
Ave. Duration:
2h 50m
Frequency:
4 times a day
Estimated price:
$12.70–$17.79

Marino Autolinee

Phone:
+39 080 3112335
Email:
Website:
marinobus.it/
Bus from Siena to Roma,
Ave. Duration:
3h 5m
Frequency:
Twice daily
Estimated price:
$29.22–$39.38

Autolinee Toscane - Linee Regionali

Phone:
+39 055 849 0505
Email:
Website:
at-bus.it/it
Bus from Siena-Via Tozzi to Firenze
Ave. Duration:
1h 15m
Frequency:
Hourly

Autolinee Federico

Phone:
+ 39 0965 644747
Email:
Website:
autolineefederico.it/
Bus from Siena to Roma,
Ave. Duration:
5h
Frequency:
Twice a week
Estimated price:
$12.07–$19.06

Curcio Viaggi

Phone:
+39 089 233 899
Email:
Website:
autolineecurcio.it/
Bus from Siena, Stazione FS to Cassino
Ave. Duration:
3h 40m
Frequency:
Once daily
Estimated price:
$1.99

ATM Azienda di Trasporti Molisana S.p.A.

Phone:
+39 0874 64744
Email:
Website:
atm-molise.it/linee/
Bus from Cassino Piazza Garibaldi to Isernia
Ave. Duration:
58 min
Frequency:
3 times a day
Estimated price:
$3.30–$4.83
Bus from Roma, Autostazione Tiburtina to Isernia
Ave. Duration:
2h 10m
Frequency:
3 times a day
Estimated price:
$10.80–$16.51

Airlines

easyJet

Website:
easyjet.com/
Plane from Florence Peretola Airport to Naples
Ave. Duration:
3h 37m
Frequency:
Monday, Wednesday, and Thursday
Estimated price:
$107.98–$431.92

Volotea

Website:
volotea.com
Plane from Florence Peretola Airport to Naples
Ave. Duration:
3h 10m
Frequency:
Monday, Thursday, Friday, and Sunday
Estimated price:
$107.98–$431.92

Alitalia

Website:
alitalia.com/
Plane from Florence Peretola Airport to Naples
Ave. Duration:
3h 30m
Frequency:
Every day
Estimated price:
$152.44–$546.26

Train operators

Trenitalia

Phone:
+39 06 68475475
Website:
trenitalia.com/
Train from Firenze S.M.N. to Roma
Ave. Duration:
4h 16m
Frequency:
Once daily
Estimated price:
$17.79–$59.71
Train from Roma Termini to Isernia
Ave. Duration:
2h 12m
Frequency:
5 times a day
Estimated price:
$13.97–$43.19
Train from Napoli Centrale to Isernia
Ave. Duration:
1h 57m
Frequency:
4 times a day
Estimated price:
$10.16–$29.22
Train from Siena to Chiusi-Chianciano
Ave. Duration:
1h 28m
Frequency:
Every 2 hours
Estimated price:
$7.62–$20.33
Train from Chiusi-Chianciano T. to Roma
Ave. Duration:
2h
Frequency:
Every 3 hours
Estimated price:
$11.43–$34.30

Trenitalia Frecce

Phone:
+39 06 68475475
Website:
trenitalia.com/en/frecce.html
Train from Firenze S.M.N. to Roma
Ave. Duration:
1h 37m
Frequency:
Every 30 minutes
Estimated price:
$26.68–$88.93

ItaloTreno

Phone:
+39 06 8937 1892
Website:
italotreno.it/it
Train from Firenze S.M.N. to Roma
Ave. Duration:
1h 36m
Frequency:
Hourly
Estimated price:
$54.63–$76.22

Trenitalia Intercity

Phone:
+39 06 68475475
Website:
trenitalia.com/
Train from Firenze S.M.N. to Roma
Ave. Duration:
2h 35m
Frequency:
6 times a week
Estimated price:
$20.33–$29.22
Train from Chiusi-Chianciano T. to Roma
Ave. Duration:
1h 45m
Frequency:
4 times a day
Estimated price:
$12.70–$19.06

Questions and Answers

What is the cheapest way to get from Siena to Isernia?

The cheapest way to get from Siena to Isernia is to bus which costs $4.46 - $5.98 and takes 5h 44m.

What is the fastest way to get from Siena to Isernia?

The fastest way to get from Siena to Isernia is to drive which takes 3h 47m and costs $65.22 - $103.26 .

Is there a direct bus between Siena and Isernia?

No, there is no direct bus from Siena to Isernia. However, there are services departing from Siena, Stazione FS and arriving at Isernia via Cassino Piazza Garibaldi. The journey, including transfers, takes approximately 5h 44m.

Is there a direct train between Siena and Isernia?

No, there is no direct train from Siena to Isernia. However, there are services departing from Siena and arriving at Isernia via Chiusi-Chianciano T. and Roma Termini. The journey, including transfers, takes approximately 7h 32m.

How far is it from Siena to Isernia?

The distance between Siena and Isernia is 391 km. The road distance is 385.1 km.

How do I travel from Siena to Isernia without a car?

The best way to get from Siena to Isernia without a car is to bus which takes 5h 44m and costs $4.46 - $5.98 .

How long does it take to get from Siena to Isernia?

It takes approximately 5h 44m to get from Siena to Isernia, including transfers.

Where do I catch the Siena to Isernia bus from?

Siena to Isernia bus services, operated by FlixBus, depart from Siena station.

Where do I catch the Siena to Isernia train from?

Siena to Isernia train services, operated by Trenitalia, depart from Siena station.

Train or bus from Siena to Isernia?

The best way to get from Siena to Isernia is to bus which takes 5h 44m and costs $4.46 - $5.98 . Alternatively, you can train, which costs $28.26 - $86.96 and takes 7h 32m.

Where does the Siena to Isernia bus arrive?

Siena to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.

Where does the Siena to Isernia train arrive?

Siena to Isernia train services, operated by Trenitalia, arrive at Chiusi-Chianciano T. station.

Can I drive from Siena to Isernia?

Yes, the driving distance between Siena to Isernia is 385 km. It takes approximately 3h 47m to drive from Siena to Isernia.

How do I get a train ticket from Siena to Isernia?

Book your Siena to Isernia train tickets online with Omio.

How do I get a bus ticket from Siena to Isernia?

Book your Siena to Isernia bus tickets online with Omio and FlixBus.

Where can I stay near Isernia?

There are 352+ hotels available in Isernia. Prices start at $28.95 per night.
→
+0 →
Transport search
Transport search