How to Travel from
Perugia to Isernia
by Car
Schedule
Perugia, Italy → Isernia, Italy
All
02 Jul 2026
July 2026
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August 2026
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September 2026
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November 2026
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December 2026
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January 2027
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February 2027
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April 2027
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May 2027
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June 2027
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All days
03 Jul, Fri
04 Jul, Sat
05 Jul, Sun
06 Jul, Mon
07 Jul, Tue
Cheapest and Fastest Ways to Travel from Perugia to Isernia
Composite routes from Perugia to Isernia
Cheapest
3 h 22 min
Car
323 km.
from $17
Route Navigator Perugia - Isernia
Get all the information you need right here
Continue
24 м
24 м
Turn right
16 м
16 м
Turn right
86 м
86 м
Turn left onto Strada di Prepo
Strada di Prepo, 1 km 573 м
1 km 573 м
Continue
4 km 622 м
4 km 622 м
Keep right
69 km 805 м
69 km 805 м
Keep right onto Strada Statale 3 bis Tiberina
Strada Statale 3 bis Tiberina, 127 м
127 м
Keep right onto Strada Statale 3 bis Tiberina and drive toward Orte, Roma, Viterbo
Strada Statale 3 bis Tiberina, Orte, Roma, Viterbo, 20 km 39 м
20 km 39 м
Keep right onto SS204 - SP151
2 km 779 м
2 km 779 м
At roundabout, take exit 3
239 м
239 м
Keep left and take A1, A24, A16, A25, A90 toward Roma, Napoli
Roma, Napoli, A1, A24, A16, A25, A90, 188 km 538 м
188 km 538 м
Keep right and drive toward San Vittore, Terme di Sulo, Castelforte, Conca della Campania, Sessa Aurunca, Venafro, Isernia, Campobasso, Agnone, Castel di Sangro, Roccaraso, S.M.I. Montelungo
San Vittore, Terme di Sulo, Castelforte, Conca della Campania, Sessa Aurunca, Venafro, Isernia, Campobasso, Agnone, Castel di Sangro, Roccaraso, S.M.I. Montelungo, 1 km 854 м
1 km 854 м
Keep left
45 м
45 м
Turn left onto Strada Regionale 430 della Valle del Garigliano Ex SS 430
Strada Regionale 430 della Valle del Garigliano Ex SS 430, 2 km 325 м
2 km 325 м
At roundabout, take exit 1 onto Via Casilina
Via Casilina, 3 km 736 м
3 km 736 м
Keep left onto SS6 Diramazione Via Casilina
SS6 Diramazione Via Casilina, 20 km 741 м
20 km 741 м
At roundabout, take exit 1 onto Strada Statale 85 Venafrana
Strada Statale 85 Venafrana, 13 km 113 м
13 km 113 м
Keep right and drive toward Isernia Santo Spirito
Isernia Santo Spirito, 206 м
206 м
Keep left and drive toward Isernia Santo Spirito
Isernia Santo Spirito, 49 м
49 м
Turn left onto Via del Rio
Via del Rio, 148 м
148 м
Keep right onto Via Santo Spirito
Via Santo Spirito, 1 km 761 м
1 km 761 м
Continue onto Via Don Luigi Sturzo
Via Don Luigi Sturzo, 217 м
217 м
Turn right onto Corso Giuseppe Garibaldi
Corso Giuseppe Garibaldi, 1 km 743 м
1 km 743 м
Turn sharp left
4 м
4 м
Arrive at destination
Transport providers
Questions and Answers
What is the cheapest way to get from Perugia to Isernia?
The cheapest way to get from Perugia to Isernia is to bus which costs $5.22 - $7.07 and takes 6h 13m.
What is the fastest way to get from Perugia to Isernia?
The fastest way to get from Perugia to Isernia is to drive which takes 3h 26m and costs $54.35 - $86.96 .
Is there a direct bus between Perugia and Isernia?
No, there is no direct bus from Perugia to Isernia. However, there are services departing from Perugia and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 30m.
Is there a direct train between Perugia and Isernia?
No, there is no direct train from Perugia to Isernia. However, there are services departing from Perugia and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 5h 47m.
How far is it from Perugia to Isernia?
The distance between Perugia and Isernia is 349 km. The road distance is 325.6 km.
How do I travel from Perugia to Isernia without a car?
The best way to get from Perugia to Isernia without a car is to bus via Rome which takes 5h 30m and costs $17.39 - $34.78 .
How long does it take to get from Perugia to Isernia?
It takes approximately 5h 30m to get from Perugia to Isernia, including transfers.
Where do I catch the Perugia to Isernia bus from?
Perugia to Isernia bus services, operated by FlixBus, depart from Perugia station.
Where do I catch the Perugia to Isernia train from?
Perugia to Isernia train services, operated by Trenitalia, depart from Perugia station.
Train or bus from Perugia to Isernia?
The best way to get from Perugia to Isernia is to bus via Rome which takes 5h 30m and costs $17.39 - $34.78 . Alternatively, you can train, which costs $23.91 - $76.09 and takes 5h 47m.
Where does the Perugia to Isernia bus arrive?
Perugia to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Where does the Perugia to Isernia train arrive?
Perugia to Isernia train services, operated by Trenitalia, arrive at Roma Termini station.
Can I drive from Perugia to Isernia?
Yes, the driving distance between Perugia to Isernia is 326 km. It takes approximately 3h 26m to drive from Perugia to Isernia.
How do I get a train ticket from Perugia to Isernia?
Book your Perugia to Isernia train tickets online with Omio.
How do I get a bus ticket from Perugia to Isernia?
Book your Perugia to Isernia bus tickets online with Omio and FlixBus.
Where can I stay near Isernia?
There are 352+ hotels available in Isernia. Prices start at $28.95 per night.
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