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How to Travel from

Mestre to Palermo

by Plane, Route or Car

Mestre
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Palermo
Transport search to Palermo
Mestre
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Palermo
Building a composite car route
Cheapest
Best Offer!
Car
21 h
1069 km.
from $58
Composite Route Car Only
Schedule

Mestre, Italy → Palermo, Italy

All
03 Jul 2026
July 2026
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04 Jul, Sat
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Cheapest and Fastest Ways to Travel from Mestre to Palermo

Composite routes from Mestre to Palermo

Cheapest
Other

Transport providers

Ryanair
Website
Ulendo Airlink
Website
Volotea
Website
Alitalia
Website
Ryanair
Website
1h 40m
Every day
$22.87–$470.06
Ulendo Airlink
Website
1h 45m
Every day
$25.41–$368.42
Volotea
Website
1h 35m
Monday, Thursday, Friday, and Sunday
$63.52–$381.13
Alitalia
Website
3h 16m
Every day
$60.98–$254.09
FlixBus
Website
Itabus
Website
Marino Autolinee
Website
Autoservizi Salemi Srl
Website
SAIS Autolinee
Website
FlixBus
Website
1h 45m
Every 3 hours
$16.52–$22.87
+49 30 300 137 300
+49 30 300 137 300
Call Contact via email
Itabus
Website
2h 10m
Every 4 hours
$9.53–$13.97
+39 06 88 93 82 32
+39 06 88 93 82 32
Call
Marino Autolinee
Website
1h 50m
Once daily
$22.87–$31.76
+39 080 3112335
+39 080 3112335
Call Contact via email
Autoservizi Salemi Srl
Website
17h 15m
Once daily
$41.92–$95.28
(+39) 0923 98.11.20
(+39) 0923 98.11.20
Call
SAIS Autolinee
Website
2h 30m
Hourly
$13.97–$20.33
800 21 10 20
800 21 10 20
Call Contact via email
Deutsche Bahn Intercity-Express
Website
Trenitalia
Website
Trenitalia Frecce
Website
ItaloTreno
Website
Trenitalia Intercity
Website
Trenitalia EuroCity
Website
Deutsche Bahn Intercity-Express
Website
1h 5m
Once daily
$38.11–$43.19
+49 30 311-682904
+49 30 311-682904
Call
Trenitalia
Website
2h 51m
Every 4 hours
$15.25–$50.82
+39 06 68475475
+39 06 68475475
Call
Trenitalia Frecce
Website
8h 46m
Once daily
$95.28–$266.79
+39 06 68475475
+39 06 68475475
Call
ItaloTreno
Website
1h 27m
Once daily
$38.11–$48.28
+39 06 8937 1892
+39 06 8937 1892
Call
Trenitalia Intercity
Website
3h
Twice daily
$17.79–$25.41
+39 06 68475475
+39 06 68475475
Call
Trenitalia EuroCity
Website
1h
Twice daily
$38.11–$95.28
+39 06 68475475
+39 06 68475475
Call Contact via email
Grandi Navi Veloci
Website
Blu Jet
Website
Grandi Navi Veloci
Website
12h
Once a week
$63.52–$121.96
+39 010 209 4591
+39 010 209 4591
Call Contact via email
Blu Jet
Website
20 min
Hourly
$3.09–$3.10
342 32 55 869
342 32 55 869
Call

Questions and Answers

What is the cheapest way to get from Mestre to Palermo?

The cheapest way to get from Mestre to Palermo is to bus and bus and ferry which costs $43.48 - $108.70 and takes 20h.

What is the fastest way to get from Mestre to Palermo?

The fastest way to get from Mestre to Palermo is to fly which takes 3h 59m and costs $29.35 - $195.65 .

Is there a direct bus between Mestre and Palermo?

No, there is no direct bus from Mestre to Palermo. However, there are services departing from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) and arriving at Palermo Terminal Bus via Bologna Pzza xx Settembre. The journey, including transfers, takes approximately 20h.

How far is it from Mestre to Palermo?

The distance between Mestre and Palermo is 857 km.

How do I travel from Mestre to Palermo without a car?

The best way to get from Mestre to Palermo without a car is to train and ferry which takes 13h 25m and costs $92.39 - $271.74 .

How long does it take to get from Mestre to Palermo?

It takes approximately 3h 59m to get from Mestre to Palermo, including transfers.

Where do I catch the Mestre to Palermo bus from?

Mestre to Palermo bus services, operated by FlixBus, depart from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) station.

Train, bus or fly from Mestre to Palermo?

The best way to get from Mestre to Palermo is to fly which takes 3h 59m and costs $29.35 - $195.65 . Alternatively, you can train, which costs $86.96 - $195.65 and takes 16h 56m, you could also bus, which costs $108.70 - $184.78 and takes 21h 30m.

Where does the Mestre to Palermo bus arrive?

Mestre to Palermo bus services, operated by FlixBus, arrive at Bologna Centrale station.

How do I get a bus ticket from Mestre to Palermo?

Book your Mestre to Palermo bus tickets online with Omio and FlixBus.

Where can I stay near Palermo?

There are 5272+ hotels available in Palermo. Prices start at $37.11 per night.
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