How to get from Santiago to Cusco by car, truck, walk, bike

Distance between Santiago and Cusco is 2219 kilometers (1376 miles).
Driving distance from Santiago to Cusco is 2880 kilometers (1786 miles)

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Route Map

4 Ways from Santiago (Chile/Region Metropolitana) to Cusco (Peru/Cusco)

Choose 1 of the options below and start your journey

Route instructions

1. Continue onto Plaza de Armas 845 m
2. Turn right onto Avenida Manuel Rodríguez Norte 150 m
3. Keep left onto Acceso Autopista Central 24.25 km
4. Keep left onto Ruta 5 Norte, 5 433.11 km
5. Keep right 672 m
6. Keep right onto Domeyko 381 m
7. Continue onto Miraflores 184 m
8. Keep right onto Miraflores 501.45 km
9. Keep right 979 m
10. Keep right onto Costanera 190 m
11. At roundabout, take exit 3 221 m
12. Turn right onto Ruta 5 Norte, 5 486.79 km
13. Continue onto Ruta 5 Norte, 5 503.58 km
14. Keep right 3.14 km
15. Keep left 661 m
16. Turn slight right onto Ruta 5 Norte, 5 105.48 km
17. At roundabout, take exit 1 onto Avenida Capitán Ávalos, 5 390 m
18. At roundabout, take exit 2 onto Avenida Capitán Ávalos, 5 2.20 km
19. Turn left onto Avenida Renato Roca 1.86 km
20. Turn right onto Santiago Arata Gandolfo 639 m
21. Continue onto Santiago Arata Gandolfo 3.19 km
22. At roundabout, take exit 2 onto Ruta 5 Norte 3.37 km
23. At roundabout, take exit 2 onto Ruta 5 Norte, 5 38.05 km
24. At roundabout, take exit 1 onto Carretera Panamericana Sur, PE-1S 4.35 km
25. At roundabout, take exit 3 onto Carretera Panamericana Sur, PE-1S 704 m
26. At roundabout, take exit 2 onto Carretera Panamericana Sur, PE-1S 1.44 km
27. Turn left onto Avenida Jorge Basadre Grohman, PE-1S 2.00 km
28. At roundabout, take exit 1 108 m
29. Turn left onto Circunvalacion Oeste 222 m
30. Keep right onto Avenida Industrial 735 m
31. Turn left onto Avenida Tarata 642 m
32. Continue onto Avenida Tarata, PE-38 759 m
33. Turn left onto Santa Cecilia 44 m
34. Turn right onto San Martín de Porres 36 m
35. Turn left 63 m
36. Turn right onto Santa Rosa 26 m
37. Turn sharp left onto PE-38 72.63 km
38. Turn left 122 m
39. Turn left 5 m
40. Turn right 35 m
41. Turn left 73 m
42. Turn right 65 m
43. Turn left onto PE-38 153.83 km
44. Continue onto Avenida Binacional, PE-36A 1.14 km
45. Keep left onto PE-38A 82.76 km
46. Turn left 460 m
47. Keep left 22 m
48. Turn left onto Carretera Longitudinal de la Sierra Sur, PE-3S 53.56 km
49. Continue onto Avenida El Ejército 679 m
50. Keep right onto Avenida El Sol 1.21 km
51. At roundabout, take exit 2 onto Avenida El Sol 235 m
52. Turn left 431 m
53. Turn slight left onto Jirón Cahuide 36 m
54. Turn right onto Avenida La Torre 1.32 km
55. Keep right 350 m
56. Turn right onto Avenida Circunvalación, PE-3S 36.20 km
57. At roundabout, take exit 1 onto Autopista Mártires del 4 de Noviembre, PE-3S 3.18 km
58. Turn slight right onto Avenida Manuel Nuñez Butron 1.77 km
59. Continue onto Manuel Nuñez Butron 780 m
60. At roundabout, take exit 2 onto Carretera Longitudinal de la Sierra Sur, PE-3S 23.84 km
61. Keep right onto PE-34B 2.45 km
62. Turn left 15.38 km
63. Turn right 12.85 km
64. Turn left onto Junín 247 m
65. Continue onto PU-117 6.90 km
66. Turn right onto PU-117 130 m
67. Turn left onto PU-117 280 m
68. Continue onto PE-3SH 3.18 km
69. Keep right onto PE-3SH 62 m
70. Turn right onto Carretera Longitudinal de la Sierra Sur, PE-3S 30.59 km
71. At roundabout, take exit 1 1.29 km
72. Turn left onto Garcilaso 2.39 km
73. At roundabout, take exit 1 onto Carretera Longitudinal de la Sierra Sur, PE-3S 104.33 km
74. Keep right onto Carretera Longitudinal de la Sierra Sur, PE-3S 926 m
75. Keep right 1.36 km
76. Turn slight right onto Jirón Juan de la Cruz Montaño 263 m
77. Turn right onto Prolongación Cantenario 115 m
78. Turn left 1.57 km
79. Turn right 28 m
80. Turn left onto Prolong Confederacion, CU-1437 62 m
81. Continue onto PE-3S 87.67 km
82. Keep left onto PE-3S 2.90 km
83. Keep left onto Avenida Mariano Santos 1.31 km
84. Continue onto PE-3S 15.85 km
85. Keep left onto PE-3S 16.13 km
86. Keep right onto Vía de Evitamiento 9.30 km
87. Turn slight right 179 m
88. Turn left onto Avenida Velasco Astete 2.01 km
89. At roundabout, take exit 3 onto Avenida 28 de julio, PE-3S 2.06 km
90. Keep right onto Avenida Tullumayo 254 m
91. Keep left onto Avenida El Sol 1.10 km
92. Turn right onto Santa Catalina Angosta 67 m
93. Arrive at destination 0 m
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Questions and Answers

What is the cheapest way to get from Santiago (Chile/Region Metropolitana) to Cusco (Peru/Cusco)?
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How long does it take to get from Santiago (Chile/Region Metropolitana) to Cusco (Peru/Cusco)?