How to get from Mainz to Prague by car, truck, walk, bike

Distance between Mainz and Prague is 439 kilometers (272 miles).
Driving distance from Mainz to Prague is 541 kilometers (335 miles)

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Route Map

4 Ways from Mainz (Germany/Hessen) to Prague (Czechia/Stredocesky Kraj)

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Route instructions

1. Continue 27 m
2. Turn left 50 m
3. Turn right onto Rheinstraße, L 431 161 m
4. Keep left onto Rheinstraße, L 431 868 m
5. Keep left onto B 40 73 m
6. At roundabout, take exit 2 onto B 455 351 m
7. At roundabout, take exit 2 onto B 455 4.39 km
8. Keep right 6.46 km
9. Keep right onto A 66 220 m
10. Keep right onto A 3 144.14 km
11. Keep right onto A 3 2.25 km
12. Continue onto A 7 416 m
13. Keep left onto A 3 17.53 km
14. Continue onto A 3 82.64 km
15. Keep right onto A 3 8.34 km
16. Keep right 157 m
17. Keep left 553 m
18. Keep right 514 m
19. Keep left 72.81 km
20. Keep right 322 m
21. Keep left 442 m
22. Keep left 189.17 km
23. Keep left 92 m
24. Turn left onto Bucharova 891 m
25. Turn sharp left 386 m
26. Turn left onto Karlštejnská 263 m
27. Turn left onto Karlštejnská 555 m
28. Turn left onto Klikatá 609 m
29. At roundabout, take exit 3 onto Klikatá 335 m
30. At roundabout, take exit 2 onto Jinonická 1.61 km
31. Keep right 823 m
32. Keep left onto Erbenova 236 m
33. Turn right onto Holečkova 1.29 km
34. Turn left onto náměstí Kinských 1.02 km
35. Turn right onto Malostranské náměstí 116 m
36. Keep right onto Malostranské náměstí 499 m
37. Continue onto Mánesův most 406 m
38. Turn sharp left onto 17. listopadu 284 m
39. Turn right onto Břehová 136 m
40. Turn sharp right onto Pařížská 427 m
41. Turn sharp right 75 m
42. Arrive at destination 0 m
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Questions and Answers

What is the cheapest way to get from Mainz (Germany/Hessen) to Prague (Czechia/Stredocesky Kraj)?
How do I get from Mainz (Germany/Hessen) to Prague (Czechia/Stredocesky Kraj) the fastest?
How long does it take to get from Mainz (Germany/Hessen) to Prague (Czechia/Stredocesky Kraj)?