How to get from Aiken to Florence by car, truck, bike, walk

The best way to get from Aiken, South Carolina to Florence, Alabama is by taking a car. Head west on SC-118 toward Pin Oak Farm Rd, then turn right onto US-1 N/US-78 E/SC-19 N/SC-382 E. Continue to follow US-78 E, then turn left to merge onto I-20 W toward Augusta. After approximately 133 miles, take exit 124 for AL-21 N/Embry-Stewart Rd toward Oxford/Anniston. Keep left at the fork and follow signs for US-78 W. Continue straight onto US-78 W, then turn right onto Choccolocco Rd. Turn left onto Leon Smith Pkwy, then merge onto AL-21 N/US-431 N/Quintard Ave. Take the AL-21 N/US-431 N exit and follow signs for US-431 N/Gadsden. Merge onto US-431 N for approximately 100 miles, then turn right onto AL-157 N towards Moulton. Drive for approximately 8 miles, then turn left onto AL-20 W. Finally, turn right onto Florence Blvd and Florence, Alabama will be on your right.\n\nAnother option is to take the Greyhound bus from Aiken, South Carolina to Florence, Alabama. You can take the Greyhound bus from the Aiken Greyhound Station located at 1128 Richland Ave W. Take the bus heading to Florence, Alabama, which will make multiple stops along the way. The travel time on the bus may be longer than driving, but it can be a more affordable option for those who don't have access to a car.