How to get from Cairo to Knoxville by car, truck, bike, walk
Distance between Cairo and Knoxville is 484 kilometers (300 miles).
Driving distance from Cairo to Knoxville is 556 kilometers (345 miles)
Route Map
Routes from cairo-illinois to knoxville-tennessee
4 Ways from Cairo (United States/Illinois) to Knoxville (United States/Tennessee)
Choose 1 of the options below and start your journey
Route instructions
1. Continue onto Washington Avenue, US 51 11 m
2. Keep left onto Washington Avenue 27 m
3. Turn sharp left onto Sycamore Street, US 51 3.05 km
4. Turn sharp left onto US 51, US 60, US 62 7.78 km
5. Turn right onto 4th Street, US 51, US 62 436 m
See more
Questions and Answers
What is the cheapest way to get from Cairo (United States/Illinois) to Knoxville (United States/Tennessee)?
How do I get from Cairo (United States/Illinois) to Knoxville (United States/Tennessee) the fastest?
How long does it take to get from Cairo (United States/Illinois) to Knoxville (United States/Tennessee)?