How to get from Durham to Knoxville by car, truck, walk, bike
Distance between Durham and Knoxville is 452 kilometers (280 miles).
Driving distance from Durham to Knoxville is 541 kilometers (335 miles)
Route Map
Routes from durham-north-carolina to knoxville-tennessee
4 Ways from Durham (United States/North Carolina) to Knoxville (United States/Tennessee)
Choose 1 of the options below and start your journey
Cheapest
Fastest
Route instructions
1. Continue onto North Corcoran Street 30 m
2. Turn left onto East Chapel Hill Street 214 m
3. Keep left onto West Chapel Hill Street 605 m
4. Turn right 72.36 km
5. Keep right onto I 40 12.31 km
See more
Questions and Answers
What is the cheapest way to get from Durham (United States/North Carolina) to Knoxville (United States/Tennessee)?
How do I get from Durham (United States/North Carolina) to Knoxville (United States/Tennessee) the fastest?
How long does it take to get from Durham (United States/North Carolina) to Knoxville (United States/Tennessee)?
Trips from Durham
DurhamMesaDurhamNormanDurhamDubuqueDurhamAndersonDurhamGreenfieldDurhamFlorenceDurhamQuincyDurhamGreenvilleDurhamLincolnTrips to Knoxville (United States/Tennessee)
SheridanKnoxvilleDes MoinesKnoxvilleTroyKnoxvilleEvansvilleKnoxvilleCaldwellKnoxvilleToledoKnoxvilleRocky MountKnoxvilleMichigan CityKnoxvilleAmsterdamKnoxvilleOther interesting routes
DelawareDistrict of ColumbiaGeorgiaMarylandNorth CarolinaSouth CarolinaVirginiaSouth CarolinaInformation about Stations
All station in Durham (United States/North Carolina)
Durham Durham Station All station in Knoxville (United States/Tennessee)
Three Rivers Rambler KnoxvilleJackson Terminal Knoxville Station 