How to get from Knoxville to Durham by car, truck, walk, bike
Distance between Knoxville and Durham is 452 kilometers (280 miles).
Driving distance from Knoxville to Durham is 541 kilometers (335 miles)
Route Map
Routes from knoxville-tennessee to durham-north-carolina
4 Ways from Knoxville (United States/Tennessee) to Durham (United States/North Carolina)
Choose 1 of the options below and start your journey
Cheapest
Fastest
Route instructions
1. Continue onto Henley Street, US 11, US 70, US 441 45 m
2. Turn left onto Main Street, US 11, US 70 2.06 km
3. Keep right 52.57 km
4. Keep right onto I 40 389.06 km
5. Keep right onto I 40 15.32 km
See more
Questions and Answers
What is the cheapest way to get from Knoxville (United States/Tennessee) to Durham (United States/North Carolina)?
How do I get from Knoxville (United States/Tennessee) to Durham (United States/North Carolina) the fastest?
How long does it take to get from Knoxville (United States/Tennessee) to Durham (United States/North Carolina)?
Trips from Knoxville
KnoxvilleEastonKnoxvilleFremontKnoxvilleCookevilleKnoxvilleLawrenceKnoxvilleElyriaKnoxvilleAtlantaKnoxvilleYorkKnoxvilleRochesterKnoxvilleSalemTrips to Durham (United States/North Carolina)
MesaDurhamBloomingtonDurhamLaurinburgDurhamDetroitDurhamEl DoradoDurhamYorkDurhamRaleighDurhamWallingfordDurhamBristolDurhamInformation about Stations
All station in Knoxville (United States/Tennessee)
Three Rivers Rambler KnoxvilleJackson Terminal Knoxville Station All station in Durham (United States/North Carolina)
Durham Durham Station 