How to get from Knoxville to Myrtle Beach by car, truck, walk, bike
Distance between Knoxville and Myrtle Beach is 524 kilometers (325 miles).
Driving distance from Knoxville to Myrtle Beach is 654 kilometers (405 miles)
Route Map
Routes from knoxville-tennessee to myrtle-beach-south-carolina
4 Ways from Knoxville (United States/Tennessee) to Myrtle Beach (United States/South Carolina)
Choose 1 of the options below and start your journey
Route instructions
1. Continue onto Henley Street, US 11, US 70, US 441 45 m
2. Turn left onto Main Street, US 11, US 70 2.06 km
3. Keep right 52.57 km
4. Keep right onto I 40 122.69 km
5. Keep right onto US 74, US 64 Truck 36.79 km
See more
Questions and Answers
What is the cheapest way to get from Knoxville (United States/Tennessee) to Myrtle Beach (United States/South Carolina)?
How do I get from Knoxville (United States/Tennessee) to Myrtle Beach (United States/South Carolina) the fastest?
How long does it take to get from Knoxville (United States/Tennessee) to Myrtle Beach (United States/South Carolina)?
Trips from Knoxville
KnoxvilleElmiraKnoxvilleRochesterKnoxvilleWilmingtonKnoxvilleBendKnoxvilleCharlotteKnoxvillePascoKnoxvilleOshkoshKnoxvilleAtlantic CityKnoxvilleOgdenTrips to Myrtle Beach (United States/South Carolina)
San MarcosMyrtle BeachVero BeachMyrtle BeachWinnipegMyrtle BeachSacramentoMyrtle BeachClearwaterMyrtle BeachMontgomeryMyrtle BeachIthacaMyrtle BeachWinston-SalemMyrtle BeachStaplesMyrtle BeachInformation about Stations
All station in Knoxville (United States/Tennessee)
Three Rivers Rambler KnoxvilleJackson Terminal Knoxville Station All station in Myrtle Beach (United States/South Carolina)
Myrtle Beach Train Depot