How to get from Missouri to Sioux Falls by car, truck, bike, walk

Distance between Missouri and Sioux Falls is 526 kilometers (326 miles).
Driving distance from Missouri to Sioux Falls is 578 kilometers (358 miles)

MissouriSioux Falls
Leaving from
Going to

Route Map

Routes from missouri-missouri to sioux-falls-south-dakota

4 Ways from Missouri (United states/Missouri) to Sioux Falls (United States/South Dakota)

Choose 1 of the options below and start your journey

Route instructions

1. Continue 49 m
2. Turn sharp right onto Troost Avenue 43 m
3. Turn left onto East 11th Street 174 m
4. Keep right 492 m
5. Keep left onto Truman/Eisenhower Presidential Highway, I 70, US 24, US 40 1.39 km
6. Keep right 227 m
7. Turn right onto US 169 8.33 km
8. Keep left 23.63 km
9. Keep left onto I 29, US 71 252.00 km
10. Keep right 564 m
11. Keep left 76 m
12. Turn left onto South Expressway 2.78 km
13. Turn left onto Willow Avenue 286 m
14. Turn right onto South 8th Street 54 m
15. Turn left onto 2nd Avenue 961 m
16. Turn right onto South 16th Street 239 m
17. Turn slight right onto North 16th Street 2.25 km
18. Keep left 280.21 km
19. Keep right onto I 29 Business 612 m
20. Continue onto I 29 Business 3.98 km
21. Turn left onto South Minnesota Avenue, I 229 BUS, SD 115 146 m
22. Turn left onto West 10th Street, I 29 BUS, SD 42 7 m
23. Arrive at destination 0 m
See more

Questions and Answers

What is the cheapest way to get from Missouri (United states/Missouri) to Sioux Falls (United States/South Dakota)?
How do I get from Missouri (United states/Missouri) to Sioux Falls (United States/South Dakota) the fastest?
How long does it take to get from Missouri (United states/Missouri) to Sioux Falls (United States/South Dakota)?