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How to Travel from

Cusco to Santiago

by Plane, Route or Car

Cusco
→
+0 →
Santiago
Transport search to Santiago
Simply select points
A and B, and we will create
a convenient route for you 👍
Peru Chile Cusco Santiago
Cusco
→
+0 →
Santiago
Building a composite car route
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A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
37 h 34 min
2824 km.
from $155
Composite Route Car Only
Schedule

Cusco, Peru → Santiago, Chile

All
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July 2026
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06 Jul, Mon
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Cheapest and Fastest Ways to Travel from Cusco to Santiago

Composite routes from Cusco to Santiago

Cheapest
37 h 34 min
Car
2824 km.
from $155
Fastest
3 h 29 min
Plane
Other
47 h 32 min
2337 km.
from $171.85
44 h 1 min
2336 km.
from $188.78
44 h 6 min
2336 km.
from $93.98
47 h 32 min
2220 km.
from $180.75
44 h 6 min
2220 km.
from $95.78

Transport providers

Airlines
Found: 3
JetSMART
Website
Sky Airline
Website
LATAM Chile
Website
JetSMART
Website
6h 40m
Wednesday, Thursday, and Saturday
$165.64–$471.43
Sky Airline
Website
7h 2m
Every day
$127.41–$509.66
LATAM Chile
Website
3h 20m
Every day
$152.90–$471.43
Bus operators
Found: 14
Pullman Bus
Website
Buses Norte Grande
Website
Peru Runa Travels
Website
Flores Hermanos
Website
Expreso Turismo San Martin Nobleza
Website
Transportes Héroes del Pacífico
Website
Turbus
Website
Ramos Cholele
Website
Pluss Chile
Website
Covalle Bus
Buses Horizonte
Website
Andoriña Tours
Hallpa
Website
Transporte Moquegua Turismo
Website
Pullman Bus
Website
29h 30m
Twice daily
$63.71–$89.19
+56 600 600 0018
+56 600 600 0018
[email protected]
Call Contact via email
Buses Norte Grande
Website
1h
Every 30 minutes
$4.75
+56 58 222 8603
+56 58 222 8603
[email protected]
Call Contact via email
Peru Runa Travels
Website
1h
Every 30 minutes
$4.75
+56 975 370 786
+56 975 370 786
[email protected]
Call Contact via email
Flores Hermanos
Website
6h
Every 3 hours
$21.66–$28.03
+51 1 4800725
+51 1 4800725
[email protected]
Call Contact via email
Expreso Turismo San Martin Nobleza
Website
15h 30m
Twice daily
$24.21–$33.13
+51 051 602 943
+51 051 602 943
Call
Transportes Héroes del Pacífico
Website
6h
Twice daily
$15.25
+51 982 802 624
+51 982 802 624
[email protected]
Call Contact via email
Turbus
Website
29h 55m
3 times a day
$50.97–$203.86
+56 22 822 7500
+56 22 822 7500
[email protected]
Call Contact via email
Ramos Cholele
Website
28h 50m
Twice daily
$49.69–$59.88
+56 57 226 9210
+56 57 226 9210
[email protected]
Call Contact via email
Pluss Chile
Website
30h
3 times a day
$44.60–$72.63
+56 22 3813 550
+56 22 3813 550
[email protected]
Call Contact via email
Covalle Bus
26h 30m
Once daily
$53.97–$58.74
+56 51 221 3127
+56 51 221 3127
Call
Buses Horizonte
Website
28h
Once daily
$63.71–$82.82
+56 9 5869 8737
+56 9 5869 8737
Call
Andoriña Tours
5h 30m
Once daily
$21.34
+51 993 585 217
+51 993 585 217
Call
Hallpa
Website
6h
Twice daily
$18.30
[email protected]
Contact via email
Transporte Moquegua Turismo
Website
6h
Every 2 hours
$21.34
+51 953 954 708
+51 953 954 708
[email protected]
Call Contact via email

Questions and Answers

What is the cheapest way to get from Cusco to Santiago?

The cheapest way to get from Cusco to Santiago is to bus which costs $65.22 - $206.52 and takes 47h 32m.

What is the fastest way to get from Cusco to Santiago?

The fastest way to get from Cusco to Santiago is to fly which takes 6h 1m and costs $119.57 - $391.30 .

Is there a direct bus between Cusco and Santiago?

No, there is no direct bus from Cusco to Santiago. However, there are services departing from Cusco and arriving at Terminal Alameda - Turbus via Arequipa, Tacna and Terminal Rodoviario de Arica. The journey, including transfers, takes approximately 44h 1m.

How far is it from Cusco to Santiago?

The distance between Cusco and Santiago is 2228 km. The road distance is 2878.3 km.

How do I travel from Cusco to Santiago without a car?

The best way to get from Cusco to Santiago without a car is to bus which takes 44h 1m and costs $76.09 - $228.26 .

How long does it take to get from Cusco to Santiago?

It takes approximately 6h 1m to get from Cusco to Santiago, including transfers.

Where do I catch the Cusco to Santiago bus from?

Cusco to Santiago bus services, operated by Andoriña Tours, depart from Cusco station.

Bus or fly from Cusco to Santiago?

The best way to get from Cusco to Santiago is to fly which takes 6h 1m and costs $119.57 - $391.30 . Alternatively, you can bus, which costs $76.09 - $228.26 and takes 44h 1m.

Where does the Cusco to Santiago bus arrive?

Cusco to Santiago bus services, operated by Andoriña Tours, arrive at Arequipa station.

What is the time difference between Cusco and Santiago?

Santiago is 2h ahead of Cusco. It is currently 02:41 in Cusco and 04:41 in Santiago.

Can I drive from Cusco to Santiago?

Yes, the driving distance between Cusco to Santiago is 2878 km. It takes approximately 35h 33m to drive from Cusco to Santiago.

Where can I stay near Santiago?

There are 2572+ hotels available in Santiago. Prices start at $49.77 per night.
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