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How to Travel from

Cusco to Guayaquil

by Plane, Route or Car

Cusco
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Guayaquil
Transport search to Guayaquil
Cusco
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Guayaquil
Building a composite car route
Cheapest
Best Offer!
Car
37 h 57 min
2472 km.
from $135
Composite Route Car Only
Schedule

Cusco, Peru → Guayaquil, Ecuador

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July 2026
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All days
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Cheapest and Fastest Ways to Travel from Cusco to Guayaquil

Composite routes from Cusco to Guayaquil

Cheapest
Fastest
Other

Transport providers

Sky Airline
Website
LATAM Chile
Website
Avianca - Aerovías del Continente Americano S.A.
Website
Sky Airline
Website
5h 55m
Tuesday and Sunday
$165.64–$496.92
LATAM Chile
Website
5h 10m
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
$242.09–$955.61
Avianca - Aerovías del Continente Americano S.A.
Website
6h 56m
Every day
$140.16–$445.95
Cruz Del Sur International
Website
Expreso Los Chankas
Website
Cruz del Sur
Website
Lineas de Los Andes
Website
Cooperativa de Transporte CIFA
Website
Oltursa
Website
Panamericana Internacional
Website
Reina del Camino
Website
Cooperativa International Ecuatoriano Pullman
Website
Cruz Del Sur International
Website
28h 30m
3 times a week
$50.97–$127.41
+51 1 311-5050
+51 1 311-5050
Call
Expreso Los Chankas
Website
21h
Twice daily
$33.13–$43.32
+51 1 3827298
+51 1 3827298
Call
Cruz del Sur
Website
21h 20m
Twice a week
$43.32–$76.45
+51 1 311 5050
+51 1 311 5050
Call
Lineas de Los Andes
Website
9h 30m
Once daily
$114.67–$152.90
+51 9 6788 4526
+51 9 6788 4526
Call Contact via email
Cooperativa de Transporte CIFA
Website
3h 30m
Every 30 minutes
$7.01–$10.83
+593 95 874 8163
+593 95 874 8163
Call Contact via email
Oltursa
Website
25h
4 times a day
$26.76–$44.60
+51 994 656 518
+51 994 656 518
Call Contact via email
Panamericana Internacional
Website
1h 17m
Twice daily
$3.82–$4.71
+593 (2) 2557133
+593 (2) 2557133
Call Contact via email
Reina del Camino
Website
57 min
Once daily
$8.92–$12.74
Cooperativa International Ecuatoriano Pullman
Website
3h
Every 30 minutes
$8.36
+593 07 293 1164
+593 07 293 1164
Call Contact via email

Questions and Answers

What is the cheapest way to get from Cusco to Guayaquil?

The cheapest way to get from Cusco to Guayaquil is to bus via Lima which costs $81.52 - $173.91 and takes 2 days 2h.

What is the fastest way to get from Cusco to Guayaquil?

The fastest way to get from Cusco to Guayaquil is to fly which takes 7h 17m and costs $206.52 - $521.74 .

Is there a direct bus between Cusco and Guayaquil?

No, there is no direct bus from Cusco to Guayaquil. However, there are services departing from Cusco and arriving at Terminal Terrestre de Guayaquil via Gran Terminal Terrestre Plaza Norte. The journey, including transfers, takes approximately 31h 30m.

How far is it from Cusco to Guayaquil?

The distance between Cusco and Guayaquil is 1543 km. The road distance is 2540.3 km.

How do I travel from Cusco to Guayaquil without a car?

The best way to get from Cusco to Guayaquil without a car is to bus which takes 31h 30m and costs $119.57 - $173.91 .

How long does it take to get from Cusco to Guayaquil?

It takes approximately 7h 17m to get from Cusco to Guayaquil, including transfers.

Where do I catch the Cusco to Guayaquil bus from?

Cusco to Guayaquil bus services, operated by Expreso Los Chankas, depart from Cusco station.

Bus or fly from Cusco to Guayaquil?

The best way to get from Cusco to Guayaquil is to fly which takes 7h 17m and costs $206.52 - $521.74 . Alternatively, you can bus, which costs $119.57 - $173.91 and takes 31h 30m.

Where does the Cusco to Guayaquil bus arrive?

Cusco to Guayaquil bus services, operated by Expreso Los Chankas, arrive at Gran Terminal Terrestre Plaza Norte station.

Can I drive from Cusco to Guayaquil?

Yes, the driving distance between Cusco to Guayaquil is 2540 km. It takes approximately 37h 30m to drive from Cusco to Guayaquil.

Where can I stay near Guayaquil?

There are 392+ hotels available in Guayaquil. Prices start at $26.72 per night.
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