How to Travel from

Santander to Madrid City Center

by Plane, Train, Bus or Car

Spain Santander Madrid City Center

Schedule

Santander, Spain → Madrid City Center, Spain

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05 Jul 2026

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Cheapest

Route Navigator Santander - Madrid City Center

Get all the information you need right here

Continue onto Calle del Río de la Pila

Calle del Río de la Pila, 97 м

97 м

Turn right onto Plaza del Río de la Pila

Plaza del Río de la Pila, 2 м

2 м

Keep right onto Calle de Guevara

Calle de Guevara, 383 м

383 м

Turn left onto Calle de Francisco de Quevedo

Calle de Francisco de Quevedo, 90 м

90 м

Turn left onto Plaza de los Remedios

Plaza de los Remedios, 40 м

40 м

Airlines

Found: 3

Train operators

Found: 1

Bus operators

Found: 2

Other operators

Found: 1

Vueling Airlines

Website

Air Europa

Website

Iberia

Website

Vueling Airlines

Website

Duration 1h 10m

Frequency Monday, Tuesday, Thursday, Friday, Saturday, and Sunday

Estimated price $43.04–$367.08

Air Europa

Website

Duration 1h 5m

Frequency Every day

Estimated price $35.44–$202.52

Iberia

Website

Duration 1h 10m

Frequency Every day

Estimated price $43.04–$367.08

Renfe Viajeros

Website

Renfe Viajeros

Website

Duration 4h

Frequency 3 times a day

Estimated price $43.04–$59.49

Phone +34 91 232 03 20

Customer Service +34 91 232 03 20

Call

ALSA

Website

FlixBus

Website

ALSA

Website

Duration 5h 30m

Frequency 4 times a day

Estimated price $41.77–$60.76

Phone +34 910 207 007

Customer Service +34 910 207 007

Email [email protected]

Call Contact via email

FlixBus

Website

Duration 1h 30m

Frequency Once daily

Estimated price $12.66–$17.72

Phone +49 30 300 137 300

Customer Service +49 30 300 137 300

Email [email protected]

Call Contact via email

BlaBlaCar.es

Website

BlaBlaCar.es

Website

Duration 5h 11m

Frequency Once a week

Estimated price $20.25–$39.24

What is the cheapest way to get from Santander to Madrid City Center?

The cheapest way to get from Santander to Madrid City Center is to rideshare which costs $17.39 - $33.70 and takes 5h 11m.

What is the fastest way to get from Santander to Madrid City Center?

The fastest way to get from Santander to Madrid City Center is to fly which takes 2h 57m and costs $34.78 - $152.17 .

Is there a direct bus between Santander and Madrid City Center?

Yes, there is a direct bus departing from Santander E.A. and arriving at Madrid, Avenida de América. Services depart four times a day, and operate every day. The journey takes approximately 5h 30m.

Is there a direct train between Santander and Madrid City Center?

No, there is no direct train from Santander to Madrid City Center. However, there are services departing from Santander and arriving at Estación de Sol Cercanías via Madrid Chamartín. The journey, including transfers, takes approximately 4h 13m.

How far is it from Santander to Madrid City Center?

The distance between Santander and Madrid City Center is 445 km. The road distance is 456.2 km.

How do I travel from Santander to Madrid City Center without a car?

The best way to get from Santander to Madrid City Center without a car is to train which takes 4h 13m and costs $39.13 - $53.26 .

How long does it take to get from Santander to Madrid City Center?

It takes approximately 4h 13m to get from Santander to Madrid City Center, including transfers.

Where do I catch the Santander to Madrid City Center bus from?

Santander to Madrid City Center bus services, operated by ALSA, depart from Santander E.A. station.

Where do I catch the Santander to Madrid City Center train from?

Santander to Madrid City Center train services, operated by Renfe Viajeros, depart from Santander station.

Train, bus or fly from Santander to Madrid City Center?

The best way to get from Santander to Madrid City Center is to train which takes 4h 13m and costs $39.13 - $53.26 . Alternatively, you can bus, which costs $35.87 - $52.17 and takes 5h 30m, you could also fly, which costs $34.78 - $152.17 and takes 2h 57m.

Where does the Santander to Madrid City Center bus arrive?

Santander to Madrid City Center bus services, operated by ALSA, arrive at Madrid, Avenida de América station.

Where does the Santander to Madrid City Center train arrive?

Santander to Madrid City Center train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.

Can I drive from Santander to Madrid City Center?

Yes, the driving distance between Santander to Madrid City Center is 456 km. It takes approximately 4h 27m to drive from Santander to Madrid City Center.

How do I get a bus ticket from Santander to Madrid City Center?

Book your Santander to Madrid City Center bus tickets online with Omio.

Where can I stay near Madrid City Center?

There are 6258+ hotels available in Madrid City Center. Prices start at $41.36 per night.

Can I share a ride from Santander to Madrid City Center?

Check out Blablacar's carpooling service for rideshare options between Santander and Madrid City Center. A great option if you don't have a driver's licence or want to avoid public transport.

Museo del Prado

The Museo del Prado (/ˈprɑːdoʊ/ PRAH-doh; Spanish pronunciation: ), officially known as Museo Nacional del Prado, is the main Spanish national art museum, located in central Madrid. It houses collections of European art, dating from the 12th century to the early 20th century, based on the former Spanish royal collection, and the single best collection of Spanish art. Founded as a museum of paintings and sculpture in 1819, it also contains important collections of other types of works. The numerous works by Francisco Goya, the single most extensively represented artist, as well as by Hieronymus Bosch, El Greco, Peter Paul Rubens, Titian, and Diego Velázquez, are some of the highlights of the collection. Velázquez and his keen eye and sensibility were also responsible for bringing much of the museum's fine collection of Italian masters to Spain, now one of the largest outside of Italy.

Royal Palace of Madrid

The Royal Palace of Madrid (Spanish: Palacio Real de Madrid) is the official residence of the Spanish royal family at the city of Madrid, although now used only for state ceremonies. The palace has 135,000 m2 (1,450,000 sq ft) of floor space and contains 3,418 rooms. It is the largest royal palace in Europe.

Matadero Madrid

Matadero Madrid is the site of a former slaughterhouse, the El Matadero y Mercado Municipal de Ganados (English: Municipal Slaughterhouse and Cattle Market) in the Arganzuela district of Madrid. Today, it is a contemporary arts centre.

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Cheapest and Fastest Ways to Travel from Santander to Madrid City Center

Composite routes from Santander to Madrid City Center

Route Navigator Santander - Madrid City Center

Transport providers

Questions and Answers

What is the cheapest way to get from Santander to Madrid City Center?

What is the fastest way to get from Santander to Madrid City Center?

Is there a direct bus between Santander and Madrid City Center?

Is there a direct train between Santander and Madrid City Center?

How far is it from Santander to Madrid City Center?

How do I travel from Santander to Madrid City Center without a car?

How long does it take to get from Santander to Madrid City Center?

Where do I catch the Santander to Madrid City Center bus from?

Where do I catch the Santander to Madrid City Center train from?

Train, bus or fly from Santander to Madrid City Center?

Where does the Santander to Madrid City Center bus arrive?

Where does the Santander to Madrid City Center train arrive?

Can I drive from Santander to Madrid City Center?

How do I get a bus ticket from Santander to Madrid City Center?

Where can I stay near Madrid City Center?

Can I share a ride from Santander to Madrid City Center?