HUB hero image

How to Travel from

Madrid to Santa Ana

by Plane, Bus or Car

Madrid
→
+0 →
Santa Ana
Transport search to Santa Ana
Simply select points
A and B, and we will create
a convenient route for you 👍
Spain Madrid Santa Ana
Madrid
→
+0 →
Santa Ana
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
4 h 9 min
412 km.
from $22
Composite Route Car Only
Schedule

Madrid, Spain → Santa Ana, Spain

All
22 May 2026
May 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
June 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
July 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
August 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
September 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
October 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
November 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
6
December 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
January 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
February 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
March 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
April 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
All days
23 May, Sat
24 May, Sun
25 May, Mon
26 May, Tue
27 May, Wed

Cheapest and Fastest Ways to Travel from Madrid to Santa Ana

Composite routes from Madrid to Santa Ana

Cheapest
4 h 9 min
Car
412 km.
from $22

Transport providers

Train operators

Renfe Viajeros

Phone:
+34 91 232 03 20
Website:
renfe.com/es/en
Train from Madrid-Atocha Cercanias to Caceres
Ave. Duration:
3h 7m
Frequency:
Every 4 hours
Estimated price:
$31.64–$44.30

Bus operators

FlixBus

Phone:
+49 30 300 137 300
Email:
Website:
flixbus.com
Bus from Estación Sur de Autobuses to Caceres
Ave. Duration:
3h 30m
Frequency:
5 times a week
Estimated price:
$29.11–$41.77

Avanza Grupo

Phone:
+34 91 272 28 32
Email:
Website:
avanzabus.com/
Bus from Madrid to Trujillo
Ave. Duration:
3h 15m
Frequency:
5 times a day
Estimated price:
$20.25–$56.96

Solis

Phone:
+34 (0) 927 38 01 27
Email:
Website:
solistour.com
Bus from Cáceres to Santa
Ave. Duration:
52 min
Frequency:
Twice daily
Estimated price:
$5.81

Questions and Answers

What is the cheapest way to get from Madrid to Santa Ana?

The cheapest way to get from Madrid to Santa Ana is to bus which costs $20.65 - $52.17 and takes 4h 40m.

What is the fastest way to get from Madrid to Santa Ana?

The fastest way to get from Madrid to Santa Ana is to drive which takes 2h 47m and costs $48.91 - $70.65 .

Is there a direct bus between Madrid and Santa Ana?

No, there is no direct bus from Madrid to Santa Ana. However, there are services departing from Madrid and arriving at Santa Ana via Trujillo. The journey, including transfers, takes approximately 4h 40m.

How far is it from Madrid to Santa Ana?

The distance between Madrid and Santa Ana is 286 km. The road distance is 281.1 km.

How do I travel from Madrid to Santa Ana without a car?

The best way to get from Madrid to Santa Ana without a car is to bus which takes 4h 40m and costs $20.65 - $52.17 .

How long does it take to get from Madrid to Santa Ana?

It takes approximately 4h 40m to get from Madrid to Santa Ana, including transfers.

Where do I catch the Madrid to Santa Ana bus from?

Madrid to Santa Ana bus services, operated by Avanza Grupo, depart from Madrid station.

Where does the Madrid to Santa Ana bus arrive?

Madrid to Santa Ana bus services, operated by Avanza Grupo, arrive at Trujillo station.

Can I drive from Madrid to Santa Ana?

Yes, the driving distance between Madrid to Santa Ana is 281 km. It takes approximately 2h 47m to drive from Madrid to Santa Ana.

Where can I stay near Santa Ana?

There are 128+ hotels available in Santa Ana. Prices start at $43.33 per night.
→
+0 →
Transport search
Transport search
On your way to Santa Ana? Choose a stop along the way
AlgortaSopelanaLeyoyaLanda