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How to Travel from

Des Moines to Winston-Salem

by Plane, Rideshare, Route or Car

Des Moines
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Winston-Salem
Transport search to Winston-Salem
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A and B, and we will create
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United States of America Des Moines Winston-Salem
Des Moines
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+0 →
Winston-Salem
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
16 h 36 min
1591 km.
from $87
Composite Route Car Only

Seven ways to Travel from Des Moines to Winston-Salem

Select an Option Below to Start Your Journey
Cheapest
By car (1 591 km)
16 h 36 min
1591 km.
from $87
Fastest
Plane to Winston-Salem
Select a ticket
Other
Rideshare
16 h 36 min
1591 km.
from $20.75
Bus, Plane (Fly to Charlotte Douglas International Airport)
5 h 40 min
1305 km.
from $340.87
Bus, Train (Bus)
24 h 53 min
1305 km.
from $264.86
Bus, Plane (Fly to Raleigh–Durham International Airport)
8 h 30 min
1305 km.
from $336.74
Bus, Train (Bus)
25 h 9 min
1305 km.
from $241.16

Transport providers

Airlines

American Airlines

Website:
aa.com/
Plane from Des Moines to Charlotte
Ave. Duration:
2h 20m
Frequency:
Every day
Estimated price:
$191.08–$891.70
Plane from Des Moines to Piedmont
Ave. Duration:
4h 38m
Frequency:
Every day
Estimated price:
$191.08–$828.01
Plane from Des Moines to Raleigh–Durham
Ave. Duration:
4h 14m
Frequency:
Every day
Estimated price:
$191.08–$891.70

Delta

Website:
delta.com/
Plane from Des Moines to Charlotte
Ave. Duration:
4h 52m
Frequency:
Every day
Estimated price:
$203.82–$496.81
Plane from Des Moines to Piedmont
Ave. Duration:
5h 14m
Frequency:
Every day
Estimated price:
$203.82–$471.33
Plane from Des Moines to Raleigh–Durham
Ave. Duration:
4h 50m
Frequency:
Every day
Estimated price:
$216.56–$484.07

United Airlines

Website:
united.com/
Plane from Des Moines to Charlotte
Ave. Duration:
4h 39m
Frequency:
Every day
Estimated price:
$254.77–$891.70
Plane from Des Moines to Piedmont
Ave. Duration:
4h 41m
Frequency:
Saturday
Estimated price:
$242.03–$828.01
Plane from Des Moines to Raleigh–Durham
Ave. Duration:
5h 2m
Frequency:
Every day
Estimated price:
$254.77–$891.70

Southwest Airlines

Website:
southwest.com/
Plane from Des Moines to Raleigh–Durham
Ave. Duration:
3h 50m
Frequency:
Monday, Thursday, and Friday
Estimated price:
$203.82–$624.19

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from Chicago Union Station to Toledo
Ave. Duration:
3h 59m
Frequency:
3 times a day
Estimated price:
$31.85–$127.39
Train from Indianapolis to Ashland
Ave. Duration:
6h 30m
Frequency:
3 times a week
Estimated price:
$35.67–$140.12

Bus operators

Greyhound USA

Phone:
+1 214-849-8100
Email:
Website:
greyhound.com/
Bus from Charlotte Bus Station to Winston
Ave. Duration:
1h 25m
Frequency:
Twice daily
Estimated price:
$6.11–$82.80
Bus from Toledo Bus Stop to Winston
Ave. Duration:
12h 35m
Frequency:
Once daily
Estimated price:
$44.59–$280.25
Bus from Durham to Winston
Ave. Duration:
1h 50m
Frequency:
3 times a day
Estimated price:
$6.37–$82.80
Bus from Ashland Bus Station to Winston
Ave. Duration:
7h 10m
Frequency:
Once daily
Estimated price:
$24.20–$178.34

Burlington Trailways

Phone:
+1 (319) 735-2864
Email:
Website:
burlingtontrailways.com
Bus from Des Moines to Chicago
Ave. Duration:
6h 10m
Frequency:
Once daily
Estimated price:
$76.43–$166.94
Bus from Des Moines to Indianapolis
Ave. Duration:
9h 30m
Frequency:
Once daily
Estimated price:
$95.54–$191.08

Barons Bus

Phone:
+1 888-378-3823
Email:
Website:
baronsbus.com/
Bus from Charlotte Bus Station to Winston
Ave. Duration:
1h 15m
Frequency:
Once daily
Estimated price:
$8.28–$47.13

Questions and Answers

What is the cheapest way to get from Des Moines to Winston-Salem?

The cheapest way to get from Des Moines to Winston-Salem is to drive which costs $173.91 - $260.87 and takes 16h 47m.

What is the fastest way to get from Des Moines to Winston-Salem?

The fastest way to get from Des Moines to Winston-Salem is to fly and bus which takes 5h 40m and costs $195.65 - $521.74 .

How far is it from Des Moines to Winston-Salem?

The distance between Des Moines and Winston-Salem is 1457 km. The road distance is 1593.1 km.

How do I travel from Des Moines to Winston-Salem without a car?

The best way to get from Des Moines to Winston-Salem without a car is to bus and train which takes 24h 53m and costs $130.43 - $500 .

How long does it take to get from Des Moines to Winston-Salem?

It takes approximately 5h 40m to get from Des Moines to Winston-Salem, including transfers.

What is the time difference between Des Moines and Winston-Salem?

Winston-Salem is 1h ahead of Des Moines. It is currently 18:52 in Des Moines and 19:52 in Winston-Salem.

Can I drive from Des Moines to Winston-Salem?

Yes, the driving distance between Des Moines to Winston-Salem is 1593 km. It takes approximately 16h 47m to drive from Des Moines to Winston-Salem.

Where can I stay near Winston-Salem?

There are 110+ hotels available in Winston-Salem. Prices start at $56.60 per night.
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