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How to Travel from

Knoxville to Sioux Falls

by Plane, Train, Route or Car

Knoxville
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Sioux Falls
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Knoxville
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Sioux Falls
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11 h 11 min
1118 km.
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Schedule

Knoxville, United States of America → Sioux Falls, United States of America

All
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April 2026
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Six ways to Travel from Knoxville to Sioux Falls

Composite routes from Knoxville to Sioux Falls

Cheapest
Other

Transport providers

Airlines

American Airlines

Website:
aa.com/
Plane from Mcghee Tyson Airport to Sioux
Ave. Duration:
5h 17m
Frequency:
Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
Estimated price:
$282.61–$1,304.35
Plane from Nashville to Sioux
Ave. Duration:
5h 1m
Frequency:
Every day
Estimated price:
$206.52–$923.91
Plane from Chattanooga Metropolitan Airport to Sioux
Ave. Duration:
6h 10m
Frequency:
Every day
Estimated price:
$260.87–$1,195.65
Plane from Asheville Regional Airport to Sioux
Ave. Duration:
6h 37m
Frequency:
Every day
Estimated price:
$250.00–$1,195.65

Delta

Website:
delta.com/
Plane from Mcghee Tyson Airport to Sioux
Ave. Duration:
4h 51m
Frequency:
Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
Estimated price:
$326.09–$706.52
Plane from Nashville to Sioux
Ave. Duration:
4h 38m
Frequency:
Every day
Estimated price:
$206.52–$500.00
Plane from Chattanooga Metropolitan Airport to Sioux
Ave. Duration:
4h 37m
Frequency:
Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
Estimated price:
$271.74–$597.83
Plane from Asheville Regional Airport to Sioux
Ave. Duration:
5h 38m
Frequency:
Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
Estimated price:
$271.74–$597.83

United Airlines

Website:
united.com/
Plane from Mcghee Tyson Airport to Sioux
Ave. Duration:
5h 10m
Frequency:
Every day
Estimated price:
$369.57–$1,304.35
Plane from Nashville to Sioux
Ave. Duration:
4h 57m
Frequency:
Every day
Estimated price:
$260.87–$869.57
Plane from Chattanooga Metropolitan Airport to Sioux
Ave. Duration:
6h 58m
Frequency:
Every day
Estimated price:
$315.22–$1,032.61
Plane from Asheville Regional Airport to Sioux
Ave. Duration:
5h 24m
Frequency:
Every day
Estimated price:
$304.35–$1,032.61

Allegiant Air

Website:
allegiantair.com/
Plane from Mcghee Tyson Airport to Sioux
Ave. Duration:
6h 59m
Frequency:
Monday, Friday, and Saturday
Estimated price:
$369.57–$1,086.96
Plane from Nashville to Sioux
Ave. Duration:
2h 19m
Frequency:
Monday and Friday
Estimated price:
$130.43–$456.52
Plane from Asheville Regional Airport to Sioux
Ave. Duration:
9h 12m
Frequency:
Monday, Friday, and Saturday
Estimated price:
$304.35–$869.57

Land to Air Express

Phone:
(888) 736-9190
Website:
landtoairexpress.com
Bus from Rochester - Airport to Albert
Ave. Duration:
1h 4m
Frequency:
Twice daily
Estimated price:
$3.91–$13.04

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Chicago
Ave. Duration:
19h 32m
Frequency:
Once daily
Estimated price:
$81.52–$282.61
Train from Chicago Union Station to Winona
Ave. Duration:
5h 29m
Frequency:
3 times a day
Estimated price:
$34.78–$130.43

Bus operators

Jefferson Lines

Phone:
+1-858-800-8898
Website:
jeffersonlines.com/
Bus from Albert Lea to Sioux
Ave. Duration:
3h 20m
Frequency:
Once daily
Estimated price:
$34.78–$86.96

NYTN Bus

Phone:
+1 615-939-8887
Website:
nytnbus.com
Bus from Knoxville to New
Ave. Duration:
13h 10m
Frequency:
3 times a week
Estimated price:
$70.65–$103.26

Questions and Answers

What is the cheapest way to get from Knoxville to Sioux Falls?

The cheapest way to get from Knoxville to Sioux Falls is to drive which costs $195.65 - $293.48 and takes 17h 51m.

What is the fastest way to get from Knoxville to Sioux Falls?

The fastest way to get from Knoxville to Sioux Falls is to fly which takes 6h 24m and costs $358.70 - $815.22 .

How far is it from Knoxville to Sioux Falls?

The distance between Knoxville and Sioux Falls is 1418 km. The road distance is 1761.3 km.

How long does it take to get from Knoxville to Sioux Falls?

It takes approximately 6h 24m to get from Knoxville to Sioux Falls, including transfers.

What is the time difference between Knoxville and Sioux Falls?

Sioux Falls is 1h behind Knoxville. It is currently 05:51 in Knoxville and 04:51 in Sioux Falls.

Can I drive from Knoxville to Sioux Falls?

Yes, the driving distance between Knoxville to Sioux Falls is 1761 km. It takes approximately 17h 51m to drive from Knoxville to Sioux Falls.

Where can I stay near Sioux Falls?

There are 82+ hotels available in Sioux Falls. Prices start at $40.59 per night.
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