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How to Travel from

Orlando to Mayo Clinic

by Route or Car

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Mayo Clinic
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Cheapest
Best Offer!
Car
24 h 37 min
2424 km.
from $133
Composite Route Car Only

Six ways to Travel from Orlando to Mayo Clinic

Select an Option Below to Start Your Journey
Cheapest
By car (2 424 km)
24 h 37 min
2424 km.
from $133
Other
Bus, Plane (Fly to La Crosse)
9 h 45 min
1982 km.
from $258.48
Bus
34 h 25 min
1980 km.
from $449.17
Train, bus via Madison, Train, bus via Madison
2 d 58 min
1982 km.
from $381.78
Bus, Plane (Fly to Minneapolis–Saint Paul International Airport)
7 h 39 min
1982 km.
from $175.63
Train, Bus
2 d 1 h 52 min
1983 km.
from $538.92

Transport providers

Airlines

Spirit Airlines

Website:
spirit.com
Plane from Orlando to Minneapolis–Saint
Ave. Duration:
3h 35m
Frequency:
Monday, Wednesday, Friday, and Saturday
Estimated price:
$204.36–$523.68

American Airlines

Website:
aa.com/
Plane from Orlando to Rochester
Ave. Duration:
6h 45m
Frequency:
Every day
Estimated price:
$204.36–$894.09
Plane from Orlando to La
Ave. Duration:
5h 53m
Frequency:
Every day
Estimated price:
$76.64–$894.09

Delta

Website:
delta.com/
Plane from Orlando to Rochester
Ave. Duration:
5h 20m
Frequency:
Every day
Estimated price:
$268.23–$523.68
Plane from Orlando to Minneapolis–Saint
Ave. Duration:
3h 36m
Frequency:
Every day
Estimated price:
$178.82–$370.41

Frontier Airlines

Website:
flyfrontier.com/
Plane from Orlando to Minneapolis–Saint
Ave. Duration:
3h 54m
Frequency:
Thursday, Saturday, and Sunday
Estimated price:
$166.04–$766.36

Southwest Airlines

Website:
southwest.com/
Plane from Orlando to Minneapolis–Saint
Ave. Duration:
5h 2m
Frequency:
Tuesday, Wednesday, Saturday, and Sunday
Estimated price:
$166.04–$485.36

Sun Country Airlines

Website:
suncountry.com/
Plane from Orlando to Minneapolis–Saint
Ave. Duration:
3h 45m
Frequency:
Every day
Estimated price:
$127.73–$625.86

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from Orlando to Chicago
Ave. Duration:
38h 55m
Frequency:
Once daily
Estimated price:
$166.04–$536.45
Train from Chicago Union Station to St.
Ave. Duration:
7h 24m
Frequency:
3 times a day
Estimated price:
$49.81–$178.82

Bus operators

Greyhound USA

Phone:
+1 214-849-8100
Email:
Website:
greyhound.com/
Bus from Orlando Bus Station to Atlanta
Ave. Duration:
7h 15m
Frequency:
3 times a day
Estimated price:
$34.49–$229.91
Bus from Atlanta Bus Station to Chicago
Ave. Duration:
16h
Frequency:
4 times a day
Estimated price:
$57.48–$344.86

Groome Transportation

Phone:
+1 (334) 821-3399
Email:
Website:
groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome
Ave. Duration:
1h 30m
Frequency:
Every 4 hours
Estimated price:
$21.71–$51.09

Flixbus USA

Phone:
+1 (855) 626-8585
Website:
flixbus.com
Bus from Orlando Bus Station to Atlanta
Ave. Duration:
8h 15m
Frequency:
4 times a day
Estimated price:
$42.15–$140.50
Bus from Atlanta Bus Station to Chicago
Ave. Duration:
14h 40m
Frequency:
Twice daily
Estimated price:
$63.86–$204.36

Jefferson Lines

Phone:
+1-858-800-8898
Email:
Website:
jeffersonlines.com/
Bus from Madison to Rochester
Ave. Duration:
4h 20m
Frequency:
Once daily
Estimated price:
$45.98–$114.95
Bus from La Crosse to Rochester
Ave. Duration:
1h 50m
Frequency:
Once daily
Estimated price:
$28.10–$63.86
Bus from St. Paul to Rochester
Ave. Duration:
1h 25m
Frequency:
Once daily
Estimated price:
$26.82–$62.59

Vangalder Bus

Phone:
+1 608-752-5407
Email:
Website:
coachusa.com/van-galder-bus-company
Bus from W Jackson Blvd, after S Clinton St to 250
Ave. Duration:
3h 35m
Frequency:
Every 2 hours
Estimated price:
$22.99–$45.98

Questions and Answers

What is the cheapest way to get from Orlando to Mayo Clinic?

The cheapest way to get from Orlando to Mayo Clinic is to fly and bus which costs $119.57 - $326.09 and takes 7h 39m.

What is the fastest way to get from Orlando to Mayo Clinic?

The fastest way to get from Orlando to Mayo Clinic is to fly and bus which takes 7h 39m and costs $119.57 - $326.09 .

Is there a direct bus between Orlando and Mayo Clinic?

No, there is no direct bus from Orlando station to Mayo Clinic. However, there are services departing from Orlando Bus Station and arriving at Rochester via Atlanta Bus Station, W Jackson Blvd, after S Clinton St and Madison. The journey, including transfers, takes approximately 34h 25m.

How far is it from Orlando to Mayo Clinic?

The distance between Orlando and Mayo Clinic is 2025 km. The road distance is 2424.6 km.

How do I travel from Orlando to Mayo Clinic without a car?

The best way to get from Orlando to Mayo Clinic without a car is to bus which takes 34h 25m and costs $130.43 - $652.17 .

How long does it take to get from Orlando to Mayo Clinic?

It takes approximately 7h 41m to get from Orlando to Mayo Clinic, including transfers.

Where do I catch the Orlando to Mayo Clinic bus from?

Orlando to Mayo Clinic bus services, operated by Greyhound USA, depart from Orlando Bus Station.

Bus or fly from Orlando to Mayo Clinic?

The best way to get from Orlando to Mayo Clinic is to fly which takes 7h 41m and costs $228.26 - $456.52 . Alternatively, you can bus, which costs $130.43 - $652.17 and takes 34h 25m.

Where does the Orlando to Mayo Clinic bus arrive?

Orlando to Mayo Clinic bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.

Can I drive from Orlando to Mayo Clinic?

Yes, the driving distance between Orlando to Mayo Clinic is 2425 km. It takes approximately 24h 35m to drive from Orlando to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 92+ hotels available in Mayo Clinic. Prices start at $50.10 per night.
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