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How to Travel from

Mayo Clinic to St. Louis

by Rideshare, Route or Car

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St. Louis
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United States of America Mayo Clinic St. Louis
Mayo Clinic
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St. Louis
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Cheapest
Best Offer!
Car
17 h 23 min
1662 km.
from $91
Composite Route Car Only

Eight ways to Travel from Mayo Clinic to St. Louis

Select an Option Below to Start Your Journey
Cheapest
By car (1 662 km)
17 h 23 min
1662 km.
from $91
Other
Rideshare
17 h 23 min
1662 km.
from $21.68
Bus, Plane (Bus to Minneapolis–Saint Paul International Airport)
4 h 39 min
628 km.
from $129.82
Bus, Train (Bus)
15 h 8 min
628 km.
from $167.88
Bus, Train (Bus)
15 h 33 min
628 km.
from $178.99
Bus, Plane (Bus to La Crosse)
7 h 40 min
628 km.
from $660
Bus, Train (Bus)
15 h 9 min
628 km.
from $173.32
Bus
16 h 33 min
627 km.
from $255.91

Transport providers

Airlines

American Airlines

Website:
aa.com/
Plane from Rochester to Lambert–St.
Ave. Duration:
5h 9m
Frequency:
Every day
Estimated price:
$204.36–$894.09
Plane from La Crosse to Lambert–St.
Ave. Duration:
5h 24m
Frequency:
Every day
Estimated price:
$281.00–$1,213.40

Delta

Website:
delta.com/
Plane from Rochester to Lambert–St.
Ave. Duration:
4h 7m
Frequency:
Every day
Estimated price:
$153.27–$485.36
Plane from Minneapolis–Saint Paul International Airport to Lambert–St.
Ave. Duration:
1h 37m
Frequency:
Every day
Estimated price:
$108.57–$344.86

Southwest Airlines

Website:
southwest.com/
Plane from Minneapolis–Saint Paul International Airport to Lambert–St.
Ave. Duration:
1h 31m
Frequency:
Every day
Estimated price:
$140.50–$447.04

Sun Country Airlines

Website:
suncountry.com/
Plane from Minneapolis–Saint Paul International Airport to Lambert–St.
Ave. Duration:
1h 34m
Frequency:
Saturday
Estimated price:
$95.79–$293.77

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from Chicago Union Station to St.
Ave. Duration:
4h 46m
Frequency:
5 times a day
Estimated price:
$37.04–$140.50
Train from St. Paul-Minneapolis to Chicago
Ave. Duration:
7h 24m
Frequency:
3 times a day
Estimated price:
$49.81–$178.82

Bus operators

Greyhound USA

Phone:
+1 214-849-8100
Email:
Website:
greyhound.com/
Bus from Milwaukee Intermodal Station to Chicago
Ave. Duration:
2h 15m
Frequency:
Twice daily
Estimated price:
$7.02–$89.41
Bus from Chicago Bus Station to St
Ave. Duration:
6h 40m
Frequency:
Once daily
Estimated price:
$26.82–$191.59

Groome Transportation

Phone:
+1 (334) 821-3399
Email:
Website:
groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis
Ave. Duration:
1h
Frequency:
Every 4 hours
Estimated price:
$21.71–$51.09

Flixbus USA

Phone:
+1 (855) 626-8585
Website:
flixbus.com
Bus from Madison to Chicago
Ave. Duration:
3h 50m
Frequency:
3 times a day
Estimated price:
$19.16–$76.64
Bus from Milwaukee Intermodal Station to Chicago
Ave. Duration:
2h
Frequency:
3 times a day
Estimated price:
$11.50–$52.37

Jefferson Lines

Phone:
+1-858-800-8898
Email:
Website:
jeffersonlines.com/
Bus from Rochester to Madison
Ave. Duration:
4h 15m
Frequency:
Once daily
Estimated price:
$45.98–$114.95
Bus from Rochester to St.
Ave. Duration:
1h 15m
Frequency:
Once daily
Estimated price:
$26.82–$62.59
Bus from Rochester to La
Ave. Duration:
1h 50m
Frequency:
Once daily
Estimated price:
$28.10–$63.86
Bus from Rochester to Milwaukee
Ave. Duration:
5h 45m
Frequency:
Once daily
Estimated price:
$56.20–$140.50

Vangalder Bus

Phone:
+1 608-752-5407
Email:
Website:
coachusa.com/van-galder-bus-company
Bus from 250 N. Lake St - Madison UW Campus to W
Ave. Duration:
4h
Frequency:
Every 2 hours
Estimated price:
$24.27–$45.98

Questions and Answers

What is the cheapest way to get from Mayo Clinic to St. Louis?

The cheapest way to get from Mayo Clinic to St. Louis is to drive which costs $76.09 - $119.57 and takes 8h 22m.

What is the fastest way to get from Mayo Clinic to St. Louis?

The fastest way to get from Mayo Clinic to St. Louis is to bus and fly which takes 4h 39m and costs $59.78 - $184.78 .

Is there a direct bus between Mayo Clinic and St. Louis?

No, there is no direct bus from Mayo Clinic to St. Louis station. However, there are services departing from Rochester and arriving at St Louis Bus Station via Milwaukee Intermodal Station and Chicago Bus Station. The journey, including transfers, takes approximately 16h 33m.

How far is it from Mayo Clinic to St. Louis?

The distance between Mayo Clinic and St. Louis is 638 km. The road distance is 725.7 km.

How do I travel from Mayo Clinic to St. Louis without a car?

The best way to get from Mayo Clinic to St. Louis without a car is to bus and train via Madison which takes 15h 8m and costs $86.96 - $282.61 .

How long does it take to get from Mayo Clinic to St. Louis?

It takes approximately 5h 51m to get from Mayo Clinic to St. Louis, including transfers.

Where do I catch the Mayo Clinic to St. Louis bus from?

Mayo Clinic to St. Louis bus services, operated by Jefferson Lines, depart from Rochester station.

Bus or fly from Mayo Clinic to St. Louis?

The best way to get from Mayo Clinic to St. Louis is to fly which takes 5h 51m and costs $130.43 - $423.91 . Alternatively, you can bus, which costs $76.09 - $358.70 and takes 16h 33m.

Where does the Mayo Clinic to St. Louis bus arrive?

Mayo Clinic to St. Louis bus services, operated by Jefferson Lines, arrive at Milwaukee station.

Can I drive from Mayo Clinic to St. Louis?

Yes, the driving distance between Mayo Clinic to St. Louis is 726 km. It takes approximately 8h 22m to drive from Mayo Clinic to St. Louis.

Where can I stay near St. Louis?

There are 430+ hotels available in St. Louis. Prices start at $41.25 per night.
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