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How to Travel from

Madison to St. Louis

by Plane, Train, Route or Car

Madison
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St. Louis
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Madison
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St. Louis
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1000 km.
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Schedule

Madison, United States of America → St. Louis, United States of America

All
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April 2026
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Five ways to Travel from Madison to St. Louis

Composite routes from Madison to St. Louis

Cheapest
Other

Transport providers

Bus operators

Greyhound USA

Phone:
+1 214-849-8100
Website:
greyhound.com/
Bus from Columbia to St
Ave. Duration:
2h 15m
Frequency:
3 times a day
Estimated price:
$8.70–$86.96

Burlington Trailways

Phone:
+1 (319) 735-2864
Website:
burlingtontrailways.com
Bus from Bowling Green to St
Ave. Duration:
1h 30m
Frequency:
Once daily
Estimated price:
$29.35–$59.78

OATS Transit

Phone:
+1-888-875-6287
Website:
oatstransit.org
Bus from Paris, MO to Hannibal
Ave. Duration:
1h
Frequency:
On demand
Estimated price:
$2.72–$3.70
Bus from Hannibal to St.
Ave. Duration:
1h 51m
Frequency:
Twice a week
Estimated price:
$4.24–$5.98

Airlines

Southern Airways Express

Website:
iflysouthern.com/
Plane from Quincy Regional Airport to Lambert–St.
Ave. Duration:
1h
Frequency:
Every day
Estimated price:
$32.61–$76.09

Questions and Answers

What is the cheapest way to get from Madison to St. Louis?

The cheapest way to get from Madison to St. Louis is to drive which costs $29.35 - $43.48 and takes 2h 57m.

What is the fastest way to get from Madison to St. Louis?

The fastest way to get from Madison to St. Louis is to drive which takes 2h 57m and costs $29.35 - $43.48 .

How far is it from Madison to St. Louis?

The distance between Madison and St. Louis is 250 km. The road distance is 272.8 km.

How do I travel from Madison to St. Louis without a car?

The best way to get from Madison to St. Louis without a car is to shuttle which takes 4h 33m and costs $54.35 - $70.65 .

How long does it take to get from Madison to St. Louis?

It takes approximately 2h 59m to get from Madison to St. Louis, including transfers.

Can I drive from Madison to St. Louis?

Yes, the driving distance between Madison to St. Louis is 273 km. It takes approximately 2h 57m to drive from Madison to St. Louis.

Where can I stay near St. Louis?

There are 464+ hotels available in St. Louis. Prices start at $39.98 per night.
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