HUB hero image

How to Travel from

St. Louis to Mayo Clinic

by Rideshare, Route or Car

St. Louis
→
+0 →
Mayo Clinic
Transport search to Mayo Clinic
Simply select points
A and B, and we will create
a convenient route for you 👍
United States of America St. Louis Mayo Clinic
St. Louis
→
+0 →
Mayo Clinic
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
17 h 19 min
1662 km.
from $91
Composite Route Car Only

Nine ways to Travel from St. Louis to Mayo Clinic

Select an Option Below to Start Your Journey
Cheapest
By car (1 662 km)
17 h 19 min
1662 km.
from $91
Other
Rideshare
17 h 19 min
1662 km.
from $21.68
Train, bus via Madison, Train, bus via Madison
14 h 58 min
628 km.
from $169.02
Train, Bus
15 h 52 min
627 km.
from $254.93
Bus, Plane (Fly Lambert–St. Louis International Airport to Minneapolis–Saint Paul International Airport)
5 h 55 min
628 km.
from $240.58
Bus, Plane (Fly Lambert–St. Louis International Airport to La Crosse)
8 h 25 min
628 km.
from $604.54
Train, Plane
10 h 29 min
628 km.
from $595.02
Train, bus via Chicago, Train, bus via Chicago
15 h 22 min
628 km.
from $164.67
Bus
17 h 25 min
627 km.
from $225.23

Transport providers

Airlines

American Airlines

Website:
aa.com/
Plane from Lambert–St. Louis International Airport to Rochester
Ave. Duration:
5h 26m
Frequency:
Every day
Estimated price:
$242.38–$1,084.33
Plane from Lambert–St. Louis International Airport to Minneapolis–Saint
Ave. Duration:
3h 49m
Frequency:
Every day
Estimated price:
$178.60–$829.20
Plane from Lambert–St. Louis International Airport to La
Ave. Duration:
4h 51m
Frequency:
Every day
Estimated price:
$229.62–$1,084.33
Plane from Abraham Lincoln Capital Airport to Rochester
Ave. Duration:
8h 34m
Frequency:
Every day
Estimated price:
$229.62–$1,084.33

Delta

Website:
delta.com/
Plane from Lambert–St. Louis International Airport to Rochester
Ave. Duration:
5h 13m
Frequency:
Every day
Estimated price:
$229.62–$829.20
Plane from Lambert–St. Louis International Airport to Minneapolis–Saint
Ave. Duration:
1h 37m
Frequency:
Every day
Estimated price:
$153.08–$395.46

Southwest Airlines

Website:
southwest.com/
Plane from Lambert–St. Louis International Airport to Minneapolis–Saint
Ave. Duration:
1h 30m
Frequency:
Every day
Estimated price:
$165.84–$612.33

Sun Country Airlines

Website:
suncountry.com/
Plane from Lambert–St. Louis International Airport to Minneapolis–Saint
Ave. Duration:
1h 35m
Frequency:
Monday
Estimated price:
$114.81–$382.71

Train operators

Amtrak

Phone:
+1 800-872-7245
Website:
amtrak.com/home.html
Train from St. Louis to Chicago
Ave. Duration:
4h 55m
Frequency:
5 times a day
Estimated price:
$36.99–$140.33
Train from Chicago Union Station to St.
Ave. Duration:
7h 24m
Frequency:
3 times a day
Estimated price:
$48.48–$178.60
Train from St. Louis to Springfield
Ave. Duration:
1h 38m
Frequency:
5 times a day
Estimated price:
$14.03–$89.30

Bus operators

Greyhound USA

Phone:
+1 214-849-8100
Email:
Website:
greyhound.com/
Bus from St Louis Bus Station to Chicago
Ave. Duration:
7h 15m
Frequency:
Once daily
Estimated price:
$26.79–$191.35

Groome Transportation

Phone:
+1 (334) 821-3399
Email:
Website:
groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome
Ave. Duration:
1h 30m
Frequency:
Every 4 hours
Estimated price:
$20.41–$49.75

Flixbus USA

Phone:
+1 (855) 626-8585
Website:
flixbus.com
Bus from Chicago Bus Station to Madison
Ave. Duration:
3h 50m
Frequency:
3 times a day
Estimated price:
$17.86–$70.16

Jefferson Lines

Phone:
+1-858-800-8898
Email:
Website:
jeffersonlines.com/
Bus from Madison to Rochester
Ave. Duration:
4h 20m
Frequency:
Once daily
Estimated price:
$44.65–$108.43
Bus from St. Paul to Rochester
Ave. Duration:
1h 25m
Frequency:
Once daily
Estimated price:
$26.79–$59.96
Bus from La Crosse to Rochester
Ave. Duration:
1h 50m
Frequency:
Once daily
Estimated price:
$26.79–$61.23

Vangalder Bus

Phone:
+1 608-752-5407
Email:
Website:
coachusa.com/van-galder-bus-company
Bus from W Jackson Blvd, after S Clinton St to 250
Ave. Duration:
3h 35m
Frequency:
Every 2 hours
Estimated price:
$22.96–$44.65

Questions and Answers

What is the cheapest way to get from St. Louis to Mayo Clinic?

The cheapest way to get from St. Louis to Mayo Clinic is to drive which costs $76.09 - $119.57 and takes 8h 25m.

What is the fastest way to get from St. Louis to Mayo Clinic?

The fastest way to get from St. Louis to Mayo Clinic is to fly and bus which takes 5h 55m and costs $119.57 - $358.70 .

Is there a direct bus between St. Louis and Mayo Clinic?

No, there is no direct bus from St. Louis station to Mayo Clinic. However, there are services departing from St Louis Bus Station and arriving at Rochester via W Jackson Blvd, after S Clinton St and Madison. The journey, including transfers, takes approximately 17h 25m.

How far is it from St. Louis to Mayo Clinic?

The distance between St. Louis and Mayo Clinic is 639 km. The road distance is 725 km.

How do I travel from St. Louis to Mayo Clinic without a car?

The best way to get from St. Louis to Mayo Clinic without a car is to train and bus via Madison which takes 14h 58m and costs $86.96 - $250 .

How long does it take to get from St. Louis to Mayo Clinic?

It takes approximately 6h 12m to get from St. Louis to Mayo Clinic, including transfers.

Where do I catch the St. Louis to Mayo Clinic bus from?

St. Louis to Mayo Clinic bus services, operated by Greyhound USA, depart from St Louis Bus Station.

Bus or fly from St. Louis to Mayo Clinic?

The best way to get from St. Louis to Mayo Clinic is to fly which takes 6h 12m and costs $195.65 - $478.26 . Alternatively, you can bus, which costs $76.09 - $293.48 and takes 17h 25m.

Where does the St. Louis to Mayo Clinic bus arrive?

St. Louis to Mayo Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.

Can I drive from St. Louis to Mayo Clinic?

Yes, the driving distance between St. Louis to Mayo Clinic is 725 km. It takes approximately 8h 25m to drive from St. Louis to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 93+ hotels available in Mayo Clinic. Prices start at $48.54 per night.
→
+0 →
Transport search
Transport search