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How to Travel from

Sioux Falls to Mayo Clinic

by Rideshare, Route or Car

Sioux Falls
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Mayo Clinic
Transport search to Mayo Clinic
Sioux Falls
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Mayo Clinic
Building a composite car route
Cheapest
Best Offer!
Car
3 h 51 min
379 km.
from $20
Composite Route Car Only

Five ways to Travel from Sioux Falls to Mayo Clinic

Select an Option Below to Start Your Journey
Cheapest
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Transport providers

Airlines

American Airlines

Website:
aa.com/
Plane from Sioux Falls to Rochester
Ave. Duration:
5h 56m
Frequency:
Every day
Estimated price:
$318.92–$1,403.25

Delta

Website:
delta.com/
Plane from Sioux Falls to Rochester
Ave. Duration:
4h 57m
Frequency:
Every day
Estimated price:
$216.87–$637.84
Plane from Sioux Falls to Minneapolis–Saint
Ave. Duration:
1h 8m
Frequency:
Every day
Estimated price:
$153.08–$459.25

Land to Air Express

Phone:
(888) 736-9190
Website:
landtoairexpress.com
Bus from Albert Lea, MN to Rochester
Ave. Duration:
1h 42m
Frequency:
Once daily
Estimated price:
$4.46–$16.58

Bus operators

Groome Transportation

Phone:
+1 (334) 821-3399
Website:
groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome
Ave. Duration:
1h 30m
Frequency:
Every 4 hours
Estimated price:
$20.41–$49.75

Jefferson Lines

Phone:
+1-858-800-8898
Website:
jeffersonlines.com/
Bus from Sioux Falls to Albert
Ave. Duration:
3h 10m
Frequency:
Once daily
Estimated price:
$39.55–$95.68
Bus from Sioux Falls to Minneapolis
Ave. Duration:
4h 45m
Frequency:
Twice daily
Estimated price:
$52.30–$127.57
Bus from Minneapolis to Rochester
Ave. Duration:
2h
Frequency:
Once daily
Estimated price:
$28.07–$63.78

Questions and Answers

What is the cheapest way to get from Sioux Falls to Mayo Clinic?

The cheapest way to get from Sioux Falls to Mayo Clinic is to drive which costs $40.22 - $59.78 and takes 3h 52m.

What is the fastest way to get from Sioux Falls to Mayo Clinic?

The fastest way to get from Sioux Falls to Mayo Clinic is to drive which takes 3h 52m and costs $40.22 - $59.78 .

Is there a direct bus between Sioux Falls and Mayo Clinic?

No, there is no direct bus from Sioux Falls to Mayo Clinic. However, there are services departing from The Bus Stop and arriving at Rochester via Sioux Falls and Minneapolis. The journey, including transfers, takes approximately 9h 8m.

How far is it from Sioux Falls to Mayo Clinic?

The distance between Sioux Falls and Mayo Clinic is 398 km. The road distance is 378.9 km.

How do I travel from Sioux Falls to Mayo Clinic without a car?

The best way to get from Sioux Falls to Mayo Clinic without a car is to bus and shuttle which takes 7h 7m and costs $38.04 - $97.83 .

How long does it take to get from Sioux Falls to Mayo Clinic?

It takes approximately 5h 30m to get from Sioux Falls to Mayo Clinic, including transfers.

Where do I catch the Sioux Falls to Mayo Clinic bus from?

Sioux Falls to Mayo Clinic bus services, operated by Jefferson Lines, depart from Sioux Falls station.

Bus or fly from Sioux Falls to Mayo Clinic?

The best way to get from Sioux Falls to Mayo Clinic is to fly which takes 6h 10m and costs $184.78 - $597.83 . Alternatively, you can bus, which costs $65.22 - $173.91 and takes 9h 8m.

Where does the Sioux Falls to Mayo Clinic bus arrive?

Sioux Falls to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Minneapolis station.

Can I drive from Sioux Falls to Mayo Clinic?

Yes, the driving distance between Sioux Falls to Mayo Clinic is 379 km. It takes approximately 3h 52m to drive from Sioux Falls to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 93+ hotels available in Mayo Clinic. Prices start at $48.54 per night.
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