How to Travel from
Santo Domingo, Ecuador to Machala
by Bus, Route or Car
Schedule
Santo Domingo, Ecuador, Ecuador → Machala, Ecuador
All
03 Jul 2026
July 2026
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All days
04 Jul, Sat
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Cheapest and Fastest Ways to Travel from Santo Domingo, Ecuador to Machala
Composite routes from Santo Domingo, Ecuador to Machala
Cheapest
6 h 9 min
Car
409 km.
from $22
Other
5 h 9 min
Bus, Plane
346 km.
from $196.32
6 h 1 min
Bus, Plane
346 km.
from $176.86
8 h 26 min
Bus, Plane
346 km.
from $110.45
7 h 42 min
Bus, Plane
346 km.
from $193.05
10 h 13 min
346 km.
from $22.20
Route Navigator Santo Domingo, Ecuador - Machala
Get all the information you need right here
Continue
60 м
60 м
Turn right
40 м
40 м
Turn right onto Avenida Emilio Lorenzo Stehle
Avenida Emilio Lorenzo Stehle, 204 м
204 м
At roundabout, take exit 1 onto Avenida Abraham Calazacón
Avenida Abraham Calazacón, 137 м
137 м
At roundabout, take exit 2 onto Avenida Esmeraldas
Avenida Esmeraldas, 2 km 788 м
2 km 788 м
At roundabout, take exit 1 onto Avenida Esmeraldas
Avenida Esmeraldas, 61 м
61 м
At roundabout, take exit 2 onto Avenida Quevedo
Avenida Quevedo, 4 km 675 м
4 km 675 м
Keep left toward E25A
E25A, 78 м
78 м
Turn right toward E25
E25, 6 м
6 м
Turn left onto Avenida Quevedo
Avenida Quevedo, 80 km 462 м
80 km 462 м
Keep left onto Avenida 7 de Agosto
Avenida 7 de Agosto, 1 km 284 м
1 km 284 м
Turn right onto Avenida 7 de Agosto
Avenida 7 de Agosto, 14 km 88 м
14 km 88 м
At roundabout, take exit 3 onto Troncal de la Costa
Troncal de la Costa, 1 km 878 м
1 km 878 м
Keep right onto Avenida Walter Andrade Fajardo
Avenida Walter Andrade Fajardo, 2 km 998 м
2 km 998 м
Keep right onto Avenida Walter Andrade Fajardo
Avenida Walter Andrade Fajardo, 6 km 277 м
6 km 277 м
Turn left onto Vía Quevedo - Mocache
Vía Quevedo - Mocache, 13 km 363 м
13 km 363 м
At roundabout, take exit 2 onto Avenida Jaime Roldos Aguilera
Avenida Jaime Roldos Aguilera, 492 м
492 м
Turn left onto 28 de Mayo
28 de Mayo, 257 м
257 м
Turn right onto Calle Primera
Calle Primera, 402 м
402 м
Keep right onto Calle Primera Baja
Calle Primera Baja, 221 м
221 м
Turn right onto Vía Mocache - Vinces
Vía Mocache - Vinces, 9 km 501 м
9 km 501 м
Turn slight left onto Vía Mocache - Aguas Frías
Vía Mocache - Aguas Frías, 11 km 921 м
11 km 921 м
Turn left onto Vía Mocache - Aguas Frías
Vía Mocache - Aguas Frías, 7 km 39 м
7 km 39 м
Turn right
2 km 642 м
2 km 642 м
Turn slight right
362 м
362 м
Turn left
1 km 26 м
1 km 26 м
Turn left onto Via Ventanas - La Yolanda
Via Ventanas - La Yolanda, 4 km 859 м
4 km 859 м
Turn right onto Troncal de la Costa
Troncal de la Costa, 42 km 92 м
42 km 92 м
At roundabout, take exit 1 onto Redondel de La Chorrera
Redondel de La Chorrera, 7 km 290 м
7 km 290 м
At roundabout, take exit 1 onto Redondel de La Reforma
Redondel de La Reforma, 7 km 315 м
7 km 315 м
Turn right
1 km 415 м
1 km 415 м
Turn right onto Troncal de la Costa
Troncal de la Costa, 22 km 724 м
22 km 724 м
Keep right toward E25
E25, 6 km 410 м
6 km 410 м
At roundabout, take exit 2 onto Avenida Jose Maria Velasco Ibarra
Avenida Jose Maria Velasco Ibarra, 7 km 398 м
7 km 398 м
At roundabout, take exit 2 onto Redondel de la Piña
Redondel de la Piña, 9 km 535 м
9 km 535 м
At roundabout, take exit 3 onto E25, E40
305 м
305 м
Keep right onto Via Naranjal
Via Naranjal, 2 km 870 м
2 km 870 м
At roundabout, take exit 2 onto Troncal de la Costa
Troncal de la Costa, 132 km 553 м
132 km 553 м
At roundabout, take exit 1
7 km 370 м
7 km 370 м
Turn right onto Avenida La Ferroviaria
Avenida La Ferroviaria, 5 km 488 м
5 km 488 м
Turn slight left onto Loja
Loja, 1 km 943 м
1 km 943 м
Turn left onto 23 de Abril
23 de Abril, 1 km 722 м
1 km 722 м
Turn right onto Calle Junín
Calle Junín, 104 м
104 м
Turn right onto Avenida Rocafuerte
Avenida Rocafuerte, 101 м
101 м
Arrive at destination
Transport providers
Airlines
Found: 5
Bus operators
Found: 8
EU
Euroairlines
TA
Transportes Azuay
Website
TO
Transportes Occidentales
Website
PI
Panamericana Internacional
Website
CD
Cooperativa de Transportes Loja Internacional
Website
CD
Cooperativa de Transportes Aerotaxi
Website
PS
Pullman Sucre Internacional
Website
CD
Cooperativa de Transportes "Kennedy"
Website
EU
Euroairlines
47 min
Monday, Wednesday, Friday, and Sunday
$126.58–$594.92
Questions and Answers
What is the cheapest way to get from Santo Domingo, Ecuador to Machala?
The cheapest way to get from Santo Domingo, Ecuador to Machala is to bus which costs $11.96 - $20.65 and takes 8h 58m.
What is the fastest way to get from Santo Domingo, Ecuador to Machala?
The fastest way to get from Santo Domingo, Ecuador to Machala is to bus and fly which takes 5h 9m and costs $70.65 - $347.83 .
Is there a direct bus between Santo Domingo, Ecuador and Machala?
Yes, there is a direct bus departing from Santo Domingo de los Colorados and arriving at Machala. Services depart every two hours, and operate every day. The journey takes approximately 8h 30m.
How far is it from Santo Domingo, Ecuador to Machala?
The distance between Santo Domingo, Ecuador and Machala is 575 km. The road distance is 421.6 km.
How do I travel from Santo Domingo, Ecuador to Machala without a car?
The best way to get from Santo Domingo, Ecuador to Machala without a car is to bus which takes 8h 58m and costs $11.96 - $20.65 .
How long does it take to get from Santo Domingo, Ecuador to Machala?
It takes approximately 5h 9m to get from Santo Domingo, Ecuador to Machala, including transfers.
Where do I catch the Santo Domingo, Ecuador to Machala bus from?
Santo Domingo, Ecuador to Machala bus services, operated by Panamericana Internacional, depart from Santo Domingo de los Colorados station.
Where does the Santo Domingo, Ecuador to Machala bus arrive?
Santo Domingo, Ecuador to Machala bus services, operated by Panamericana Internacional, arrive at Machala station.
Can I drive from Santo Domingo, Ecuador to Machala?
Yes, the driving distance between Santo Domingo, Ecuador to Machala is 422 km. It takes approximately 6h 2m to drive from Santo Domingo, Ecuador to Machala.
Where can I stay near Machala?
There are 68+ hotels available in Machala. Prices start at $30.71 per night.
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