How to get from Knoxville to Buffalo by car, truck, walk, bike

Distance between Knoxville and Buffalo is 1961 kilometers (1216 miles).
Driving distance from Knoxville to Buffalo is 2509 kilometers (1556 miles)

KnoxvilleBuffalo
Leaving from
Going to

Route Map

4 Ways from Knoxville (United States/Tennessee) to Buffalo (United States/South Dakota)

Choose 1 of the options below and start your journey

Route instructions

1. Continue onto Henley Street, US 11, US 70, US 441 45 m
2. Make a U-turn onto Henley Street, US 11, US 70, US 441 634 m
3. Keep left onto Western Avenue, SR 62 1.08 km
4. Turn left onto Ailor Avenue 11 m
5. Turn slight right onto Ailor Avenue 692 m
6. Keep left 29.95 km
7. Keep right onto I 40 245.86 km
8. Keep right 18.68 km
9. Keep right 178.96 km
10. Keep right onto I 24 102.05 km
11. Keep left 83.85 km
12. Keep left onto I 64 89.31 km
13. Turn left onto I 64, US 50 24.46 km
14. Keep right 391.95 km
15. Keep right 5.36 km
16. Keep left onto Lamar Hunt Memorial Highway, I 435 44.69 km
17. Keep left onto I 29, US 71 252.00 km
18. Keep right 564 m
19. Keep left 76 m
20. Turn left onto South Expressway 2.78 km
21. Turn left onto Willow Avenue 286 m
22. Turn right onto South 8th Street 54 m
23. Turn left onto 2nd Avenue 961 m
24. Turn right onto South 16th Street 239 m
25. Turn slight right onto North 16th Street 2.25 km
26. Keep left 288.76 km
27. Keep right 599.13 km
28. Keep right 446 m
29. Turn right onto SD 34 27.90 km
30. Turn right onto 5th Avenue, US 85 116.18 km
31. Arrive at destination 0 m
See more

Questions and Answers

What is the cheapest way to get from Knoxville (United States/Tennessee) to Buffalo (United States/South Dakota)?
How do I get from Knoxville (United States/Tennessee) to Buffalo (United States/South Dakota) the fastest?
How long does it take to get from Knoxville (United States/Tennessee) to Buffalo (United States/South Dakota)?

Information about Stations

All station in Knoxville (United States/Tennessee)
Three Rivers Rambler KnoxvilleJackson Terminal Knoxville Station
All station in Buffalo (United States/South Dakota)
Municipal Buffalo