HUB hero image

How to Travel from

Panama City to Santa Fe

by Car

Panama City
→
+0 →
Santa Fe
Transport search to Santa Fe
Simply select points
A and B, and we will create
a convenient route for you 👍
Panama hat Panama City Santa Fe
Panama City
→
+0 →
Santa Fe
Building a composite car route
Simply select points
A and B, and we will create
a convenient route for you 👍
To build a composite route, click the "Add point" button.
You can also move and delete intermediate points.
Cheapest
Best Offer!
Car
4 h 19 min
305 km.
from $16
Composite Route Car Only
Schedule

Panama City, Panama hat → Santa Fe, Panama hat

All
28 May 2026
May 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
June 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
July 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
August 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
September 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
October 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
November 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
26
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3
4
5
6
December 2026
Mon
Tue
Wed
Thu
Fri
Sat
Sun
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
January 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
February 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
March 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
April 2027
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
All days
29 May, Fri
30 May, Sat
31 May, Sun
01 Jun, Mon
02 Jun, Tue

Cheapest and Fastest Ways to Travel from Panama City to Santa Fe

Composite routes from Panama City to Santa Fe

Cheapest
4 h 19 min
Car
305 km.
from $16

Transport providers

Bus operators

Union de Transportistas Penonome

Phone:
+507 303-6466
Bus from Panama Albrook to San
Ave. Duration:
1h 10m
Frequency:
Every 15 minutes
Estimated price:
$4.68

Transporte Panama Chiriqui Frontera S.A (Panachif)

Phone:
+507 6265 8842
Website:
facebook.com/profile.php/?id=100063606474316
Bus from Albrook to Santiago
Ave. Duration:
4h
Frequency:
Every 2 hours
Estimated price:
$13.11
Bus from David to Santiago
Ave. Duration:
2h 30m
Frequency:
Every 2 hours
Estimated price:
$10.63

Unión de transportistas de La Pintada

Phone:
+507 987 2557
Website:
instagram.com/utralap_sa1
Bus from Panama Albrook to San
Ave. Duration:
1h 36m
Frequency:
Twice daily
Estimated price:
$5.30
Bus from Panama City - Albrook to Penonomé
Ave. Duration:
2h 43m
Frequency:
Twice daily
Estimated price:
$6.14

Terminales Panama David

Phone:
+507 775-2974
Email:
Website:
instagram.com/terminales_davidpanama
Bus from San Carlos to La
Ave. Duration:
2h 21m
Frequency:
Hourly

Panamá Regional Buses

Bus from Santiago to Santa
Ave. Duration:
50 min
Frequency:
Every 30 minutes
Estimated price:
$2.39–$3.48
Bus from Chitré to Ocu
Ave. Duration:
1h
Frequency:
Every 30 minutes
Estimated price:
$2.07–$2.93
Bus from Ocu to Santiago
Ave. Duration:
1h
Frequency:
Every 20 minutes
Estimated price:
$1.96–$2.93

SANPASA

Phone:
+(507) 314-6231
Website:
facebook.com/profile.php?id=100004352746318
Bus from Albrook to Santiago
Ave. Duration:
5h
Frequency:
Every 30 minutes
Estimated price:
$10.82
Bus from Panama City - Albrook to Penonomé
Ave. Duration:
2h 57m
Frequency:
Every 30 minutes
Estimated price:
$9.58
Bus from Penonomé to Santiago
Ave. Duration:
2h 3m
Frequency:
Every 30 minutes

Expreso Veraguense

Phone:
+507958-6484
Website:
instagram.com/expreso_veraguense_sa/
Bus from Albrook to Santiago
Ave. Duration:
4h 30m
Frequency:
Every 5 minutes
Estimated price:
$8.85

Airlines

Air Panama

Website:
airpanama.com/home.php
Plane from Albrook Marcos A. Gelabert International Airport to Chitre
Ave. Duration:
30 min
Frequency:
Tuesday to Sunday
Estimated price:
$108.70–$282.61
Plane from Albrook Marcos A. Gelabert International Airport to David
Ave. Duration:
1h
Frequency:
Every day
Estimated price:
$81.52–$260.87

Questions and Answers

What is the cheapest way to get from Panama City to Santa Fe?

The cheapest way to get from Panama City to Santa Fe is to bus which costs $10.87 - $17.39 and takes 5h 35m.

What is the fastest way to get from Panama City to Santa Fe?

The fastest way to get from Panama City to Santa Fe is to fly and taxi and bus which takes 3h 27m and costs $869.57 - $2282.61 .

Is there a direct bus between Panama City and Santa Fe?

No, there is no direct bus from Panama City to Santa Fe. However, there are services departing from Albrook and arriving at Santa Fé via Santiago. The journey, including transfers, takes approximately 5h 35m.

How far is it from Panama City to Santa Fe?

The distance between Panama City and Santa Fe is 315 km. The road distance is 306 km.

How do I travel from Panama City to Santa Fe without a car?

The best way to get from Panama City to Santa Fe without a car is to bus which takes 5h 35m and costs $10.87 - $17.39 .

How long does it take to get from Panama City to Santa Fe?

It takes approximately 5h 35m to get from Panama City to Santa Fe, including transfers.

Where do I catch the Panama City to Santa Fe bus from?

Panama City to Santa Fe bus services, operated by Expreso Veraguense, depart from Albrook station.

Where does the Panama City to Santa Fe bus arrive?

Panama City to Santa Fe bus services, operated by Expreso Veraguense, arrive at Santiago station.

Can I drive from Panama City to Santa Fe?

Yes, the driving distance between Panama City to Santa Fe is 306 km. It takes approximately 4h 19m to drive from Panama City to Santa Fe.

Where can I stay near Santa Fe?

There are five+ hotels available in Santa Fe. Prices start at $43.23 per night.
→
+0 →
Transport search
Transport search